BindingDB logo
myBDB logout

Articleid 50034817

Compile data set for download or QSAR
Found 40 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286369
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-naphthalen-2-y...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc3ccccc3c2)\[#7]=[#6](\[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C45H67N4OP/c1-4-7-30-51(31-8-5-2,32-9-6-3)35-36-25-28-42(29-26-36)46-44(50)43(34-37-24-27-38-18-16-17-19-39(38)33-37)49-45(47-40-20-12-10-13-21-40)48-41-22-14-11-15-23-41/h16-19,24-29,33,40-41,43H,4-15,20-23,30-32,34-35H2,1-3H3,(H2-,46,47,48,49,50)/p+1/t43-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
 60n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286372
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-naphthalen-2-y...)
Show SMILES [#6]-[#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc3ccccc3c2)\[#7]=[#6](/[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C48H73N4OP/c1-4-7-18-33-54(34-19-8-5-2,35-20-9-6-3)38-39-28-31-45(32-29-39)49-47(53)46(37-40-27-30-41-21-16-17-22-42(41)36-40)52-48(50-43-23-12-10-13-24-43)51-44-25-14-11-15-26-44/h16-17,21-22,27-32,36,43-44,46H,4-15,18-20,23-26,33-35,37-38H2,1-3H3,(H2-,49,50,51,52,53)/p+1/t46-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 60n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286365
PNG
(2-(N',N''-Dicyclohexyl-N-methyl-guanidino)-3-napht...)
Show SMILES CCCC[P+](CCCC)(CCCC)Cc1ccc(NC(=O)[C@H](Cc2ccc3ccccc3c2)N(C)C(\NC2CCCCC2)=N\C2CCCCC2)cc1 |r|
Show InChI InChI=1S/C46H69N4OP/c1-5-8-31-52(32-9-6-2,33-10-7-3)36-37-26-29-43(30-27-37)47-45(51)44(35-38-25-28-39-19-17-18-20-40(39)34-38)50(4)46(48-41-21-13-11-14-22-41)49-42-23-15-12-16-24-42/h17-20,25-30,34,41-42,44H,5-16,21-24,31-33,35-36H2,1-4H3,(H-,47,48,49,51)/p+1/t44-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 70n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286357
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-naphthalen-2-y...)
Show SMILES O=[#6](-[#7]-c1ccc(-[#6][P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1)-[#6@H](-[#6]-c1ccc2ccccc2c1)\[#7]=[#6](/[#7]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#7]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 |r|
Show InChI InChI=1S/C51H55N4OP/c56-50(52-45-34-31-39(32-35-45)38-57(46-24-10-3-11-25-46,47-26-12-4-13-27-47)48-28-14-5-15-29-48)49(37-40-30-33-41-18-16-17-19-42(41)36-40)55-51(53-43-20-6-1-7-21-43)54-44-22-8-2-9-23-44/h3-5,10-19,24-36,43-44,49H,1-2,6-9,20-23,37-38H2,(H2-,52,53,54,55,56)/p+1/t49-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 110n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286383
PNG
((S)-2-(N',N''-Di-p-tolyl-guanidino)-3-naphthalen-2...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@@H](-[#6]-c2ccc3ccccc3c2)\[#7]=[#6](\[#7]-c2ccc(-[#6])cc2)-[#7]-c2ccc(-[#6])cc2)cc1 |r|
Show InChI InChI=1S/C47H59N4OP/c1-6-9-30-53(31-10-7-2,32-11-8-3)35-38-21-28-42(29-22-38)48-46(52)45(34-39-20-23-40-14-12-13-15-41(40)33-39)51-47(49-43-24-16-36(4)17-25-43)50-44-26-18-37(5)19-27-44/h12-29,33,45H,6-11,30-32,34-35H2,1-5H3,(H2-,48,49,50,51,52)/p+1/t45-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 140n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286388
PNG
(N,N'-Dicyclohexyl-N''-{(E)-(S)-1-naphthalen-2-ylme...)
Show SMILES CCCC[P+](CCCC)(CCCC)Cc1ccc(\C=C\[C@H](Cc2ccc3ccccc3c2)N\C(NC2CCCCC2)=[NH+]\C2CCCCC2)cc1
Show InChI InChI=1S/C46H69N3P/c1-4-7-32-50(33-8-5-2,34-9-6-3)37-39-26-24-38(25-27-39)29-31-45(36-40-28-30-41-18-16-17-19-42(41)35-40)49-46(47-43-20-12-10-13-21-43)48-44-22-14-11-15-23-44/h16-19,24-31,35,43-45H,4-15,20-23,32-34,36-37H2,1-3H3,(H2,47,48,49)/q+1/p+1/b31-29+/t45-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 250n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5


(RAT)		BDBM50286369
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-naphthalen-2-y...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc3ccccc3c2)\[#7]=[#6](\[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C45H67N4OP/c1-4-7-30-51(31-8-5-2,32-9-6-3)35-36-25-28-42(29-26-36)46-44(50)43(34-37-24-27-38-18-16-17-19-39(38)33-37)49-45(47-40-20-12-10-13-21-40)48-41-22-14-11-15-23-41/h16-19,24-29,33,40-41,43H,4-15,20-23,30-32,34-35H2,1-3H3,(H2-,46,47,48,49,50)/p+1/t43-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
 350n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards rat muscarinic receptor

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286393
PNG
((NE)-N-({[(1S)-1-({1-azabicyclo[2.2.2]octan-3-yl}c...)
Show SMILES O=C(NC1CN2CCC1CC2)[C@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1 |wD:11.26,(15.08,-7.56,;14.92,-9.11,;16.18,-10.02,;17.73,-10.02,;18.49,-11.36,;20.06,-11.31,;18.72,-10.54,;19.83,-9.46,;18.49,-8.69,;20.03,-8.69,;20.8,-10.02,;13.51,-9.74,;13.34,-11.29,;14.12,-12.63,;13.34,-13.94,;14.1,-15.28,;15.63,-15.28,;16.39,-16.61,;17.93,-16.64,;18.7,-15.3,;17.94,-13.96,;16.4,-13.96,;15.64,-12.63,;12.25,-8.83,;10.75,-8.43,;9.65,-9.51,;8.1,-9.51,;6.78,-10,;5.33,-9.51,;4.43,-10.75,;5.61,-10.37,;7.34,-10.89,;10.35,-6.93,;8.85,-6.53,;7.53,-7,;6.08,-6.5,;5.18,-7.77,;6.36,-7.4,;8.09,-7.91,)|
Show InChI InChI=1S/C33H47N5O/c39-32(36-31-23-38-19-17-26(31)18-20-38)30(22-24-15-16-25-9-7-8-10-27(25)21-24)37-33(34-28-11-3-1-4-12-28)35-29-13-5-2-6-14-29/h7-10,15-16,21,26,28-31H,1-6,11-14,17-20,22-23H2,(H,36,39)(H2,34,35,37)/p+1/t30-,31?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 410n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286390
PNG
(3-Benzo[b]thiophen-2-yl-2-(N',N''-dicyclohexyl-gua...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2cc3ccccc3s2)\[#7]=[#6](/[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C43H65N4OPS/c1-4-7-28-49(29-8-5-2,30-9-6-3)33-34-24-26-38(27-25-34)44-42(48)40(32-39-31-35-18-16-17-23-41(35)50-39)47-43(45-36-19-12-10-13-20-36)46-37-21-14-11-15-22-37/h16-18,23-27,31,36-37,40H,4-15,19-22,28-30,32-33H2,1-3H3,(H2-,44,45,46,47,48)/p+1/t40-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 430n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286364
PNG
((NE)-N-({[1-({1-azabicyclo[2.2.2]octan-3-yl}carbam...)
Show SMILES O=C(NC1CN2CCC1CC2)C(Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1 |(12.05,-2.05,;11.9,-3.6,;13.16,-4.51,;14.7,-4.51,;15.46,-5.85,;17.03,-5.8,;15.7,-5.03,;16.8,-3.95,;15.46,-3.17,;17,-3.17,;17.78,-4.51,;10.48,-4.23,;10.32,-5.78,;11.09,-7.11,;10.32,-8.43,;11.07,-9.76,;12.6,-9.76,;13.37,-11.1,;14.9,-11.12,;15.67,-9.79,;14.92,-8.45,;13.38,-8.45,;12.62,-7.11,;9.22,-3.31,;7.72,-2.92,;6.62,-3.99,;5.07,-3.99,;3.75,-4.49,;2.31,-3.99,;1.41,-5.24,;2.58,-4.86,;4.32,-5.38,;7.33,-1.42,;5.82,-1.02,;4.5,-1.49,;3.06,-.99,;2.16,-2.26,;3.33,-1.88,;5.07,-2.4,)|
Show InChI InChI=1S/C33H47N5O/c39-32(36-31-23-38-19-17-26(31)18-20-38)30(22-24-15-16-25-9-7-8-10-27(25)21-24)37-33(34-28-11-3-1-4-12-28)35-29-13-5-2-6-14-29/h7-10,15-16,21,26,28-31H,1-6,11-14,17-20,22-23H2,(H,36,39)(H2,34,35,37)/p+1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 550n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286364
PNG
((NE)-N-({[1-({1-azabicyclo[2.2.2]octan-3-yl}carbam...)
Show SMILES O=C(NC1CN2CCC1CC2)C(Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1 |(12.05,-2.05,;11.9,-3.6,;13.16,-4.51,;14.7,-4.51,;15.46,-5.85,;17.03,-5.8,;15.7,-5.03,;16.8,-3.95,;15.46,-3.17,;17,-3.17,;17.78,-4.51,;10.48,-4.23,;10.32,-5.78,;11.09,-7.11,;10.32,-8.43,;11.07,-9.76,;12.6,-9.76,;13.37,-11.1,;14.9,-11.12,;15.67,-9.79,;14.92,-8.45,;13.38,-8.45,;12.62,-7.11,;9.22,-3.31,;7.72,-2.92,;6.62,-3.99,;5.07,-3.99,;3.75,-4.49,;2.31,-3.99,;1.41,-5.24,;2.58,-4.86,;4.32,-5.38,;7.33,-1.42,;5.82,-1.02,;4.5,-1.49,;3.06,-.99,;2.16,-2.26,;3.33,-1.88,;5.07,-2.4,)|
Show InChI InChI=1S/C33H47N5O/c39-32(36-31-23-38-19-17-26(31)18-20-38)30(22-24-15-16-25-9-7-8-10-27(25)21-24)37-33(34-28-11-3-1-4-12-28)35-29-13-5-2-6-14-29/h7-10,15-16,21,26,28-31H,1-6,11-14,17-20,22-23H2,(H,36,39)(H2,34,35,37)/p+1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 550n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286367
PNG
(N,N'-Dicyclohexyl-N''-{(Z)-(S)-1-naphthalen-2-ylme...)
Show SMILES CCCC[P+](CCCC)(CCCC)Cc1ccc(\C=C/[C@H](Cc2ccc3ccccc3c2)N\C(NC2CCCCC2)=[NH+]\C2CCCCC2)cc1
Show InChI InChI=1S/C46H69N3P/c1-4-7-32-50(33-8-5-2,34-9-6-3)37-39-26-24-38(25-27-39)29-31-45(36-40-28-30-41-18-16-17-19-42(41)35-40)49-46(47-43-20-12-10-13-21-43)48-44-22-14-11-15-23-44/h16-19,24-31,35,43-45H,4-15,20-23,32-34,36-37H2,1-3H3,(H2,47,48,49)/q+1/p+1/b31-29-/t45-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 760n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286392
PNG
(Bis-[4-(tripentyl-lambda*5*-phosphanylmethyl)-phen...)
Show SMILES CCCCC[P+](CCCCC)(CCCCC)Cc1ccc(cc1)C(=O)c1ccc(C[P+](CCCCC)(CCCCC)CCCCC)cc1
Show InChI InChI=1S/C45H78OP2/c1-7-13-19-33-47(34-20-14-8-2,35-21-15-9-3)39-41-25-29-43(30-26-41)45(46)44-31-27-42(28-32-44)40-48(36-22-16-10-4,37-23-17-11-5)38-24-18-12-6/h25-32H,7-24,33-40H2,1-6H3/q+2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 770n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286370
PNG
(N-(1-Aza-bicyclo[2.2.2]oct-3-yl)-N-benzyl-2-(N',N'...)
Show SMILES O=C([C@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1)N(Cc1ccccc1)C1CN2CCC1CC2 |wD:2.15,(15.08,-7.7,;14.92,-9.22,;13.51,-9.86,;13.34,-11.4,;12.24,-12.51,;13.01,-13.82,;12.26,-15.16,;10.72,-15.16,;9.97,-16.49,;8.43,-16.52,;7.64,-15.18,;8.42,-13.84,;9.94,-13.84,;10.7,-12.51,;12.25,-8.97,;10.75,-8.54,;9.65,-9.65,;8.1,-9.62,;6.78,-10.11,;5.33,-9.62,;4.43,-10.89,;5.6,-10.49,;7.34,-11.03,;10.35,-7.04,;8.85,-6.64,;7.53,-7.14,;6.08,-6.64,;5.18,-7.89,;6.35,-7.51,;8.09,-8.03,;16.18,-10.14,;16.16,-11.69,;16.93,-13.02,;18.46,-13.02,;19.23,-14.36,;18.46,-15.7,;16.92,-15.7,;16.16,-14.36,;17.73,-10.14,;18.49,-11.47,;20.06,-11.45,;20.8,-10.14,;20.03,-8.8,;18.49,-8.8,;19.82,-9.58,;18.72,-10.68,)|
Show InChI InChI=1S/C40H53N5O/c46-39(45(28-30-12-4-1-5-13-30)38-29-44-24-22-33(38)23-25-44)37(27-31-20-21-32-14-10-11-15-34(32)26-31)43-40(41-35-16-6-2-7-17-35)42-36-18-8-3-9-19-36/h1,4-5,10-15,20-21,26,33,35-38H,2-3,6-9,16-19,22-25,27-29H2,(H2,41,42,43)/p+1/t37-,38?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 820n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286381
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-naphthalen-1-y...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2cccc3ccccc23)\[#7]=[#6](\[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C45H67N4OP/c1-4-7-31-51(32-8-5-2,33-9-6-3)35-36-27-29-41(30-28-36)46-44(50)43(34-38-21-18-20-37-19-16-17-26-42(37)38)49-45(47-39-22-12-10-13-23-39)48-40-24-14-11-15-25-40/h16-21,26-30,39-40,43H,4-15,22-25,31-35H2,1-3H3,(H2-,46,47,48,49,50)/p+1/t43-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 1.03E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286382
PNG
(4-(Tripentyl-lambda*5*-phosphanylmethyl)-N-[4-(tri...)
Show SMILES CCCCC[P+](CCCCC)(CCCCC)Cc1ccc(NC(=O)c2ccc(C[P+](CCCCC)(CCCCC)CCCCC)cc2)cc1
Show InChI InChI=1S/C45H78NOP2/c1-7-13-19-33-48(34-20-14-8-2,35-21-15-9-3)39-41-25-29-43(30-26-41)45(47)46-44-31-27-42(28-32-44)40-49(36-22-16-10-4,37-23-17-11-5)38-24-18-12-6/h25-32H,7-24,33-40H2,1-6H3/q+1/p+1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
 1.10E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286389
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-naphthalen-2-y...)
Show SMILES O=C(Nc1cnc2ccccc2c1)[C@@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1
Show InChI InChI=1S/C35H41N5O/c41-34(37-31-23-28-13-9-10-18-32(28)36-24-31)33(22-25-19-20-26-11-7-8-12-27(26)21-25)40-35(38-29-14-3-1-4-15-29)39-30-16-5-2-6-17-30/h7-13,18-21,23-24,29-30,33H,1-6,14-17,22H2,(H,37,41)(H2,38,39,40)/p+1/t33-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 1.30E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286366
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-N-isoquinolin-8-...)
Show SMILES O=C(Nc1cccc2ccncc12)[C@@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1
Show InChI InChI=1S/C35H41N5O/c41-34(39-32-17-9-12-27-20-21-36-24-31(27)32)33(23-25-18-19-26-10-7-8-11-28(26)22-25)40-35(37-29-13-3-1-4-14-29)38-30-15-5-2-6-16-30/h7-12,17-22,24,29-30,33H,1-6,13-16,23H2,(H,39,41)(H2,37,38,40)/p+1/t33-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 2.54E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286361
PNG
(CHEMBL540641 | Tributyl-{4-[2-(N',N''-dicyclohexyl...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2cccs2)\[#7]=[#6](/[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C39H63N4OPS/c1-4-7-26-45(27-8-5-2,28-9-6-3)31-32-22-24-35(25-23-32)40-38(44)37(30-36-21-16-29-46-36)43-39(41-33-17-12-10-13-18-33)42-34-19-14-11-15-20-34/h16,21-25,29,33-34,37H,4-15,17-20,26-28,30-31H2,1-3H3,(H2-,40,41,42,43,44)/p+1/t37-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 2.57E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286371
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-(1H-indol-3-yl...)
Show SMILES CCCC[P+](CCCC)(CCCC)Cc1ccc(NC(=O)[C@H](Cc2c[nH]c3ccccc23)N=C(NC2CCCCC2)NC2CCCCC2)cc1 |r,wD:21.33,(22.86,-8.3,;21.34,-8.63,;20.86,-10.08,;19.35,-10.38,;18.88,-11.85,;20.15,-12.69,;21.52,-12.01,;22.81,-12.86,;24.19,-12.16,;18.02,-13.13,;18.71,-14.51,;17.87,-15.78,;18.56,-17.16,;18.18,-10.47,;16.66,-10.61,;15.68,-11.81,;14.14,-11.55,;13.62,-10.12,;12.08,-10.12,;10.82,-9.21,;10.99,-7.69,;9.42,-9.84,;9.26,-11.39,;10.02,-12.71,;11.56,-12.88,;11.85,-14.38,;10.52,-15.12,;10.19,-16.61,;8.72,-17.06,;7.6,-16.03,;7.94,-14.54,;9.4,-14.07,;8.16,-8.95,;6.67,-8.53,;5.57,-9.63,;4.03,-9.63,;3.26,-8.28,;1.71,-8.27,;.94,-9.6,;1.71,-10.94,;3.26,-10.96,;6.27,-7.04,;4.77,-6.63,;4.38,-5.12,;2.9,-4.72,;1.78,-5.8,;2.17,-7.31,;3.68,-7.72,;14.59,-8.92,;16.1,-9.17,)|
Show InChI InChI=1S/C43H66N5OP/c1-4-7-28-50(29-8-5-2,30-9-6-3)33-34-24-26-38(27-25-34)45-42(49)41(31-35-32-44-40-23-17-16-22-39(35)40)48-43(46-36-18-12-10-13-19-36)47-37-20-14-11-15-21-37/h16-17,22-27,32,36-37,41,44H,4-15,18-21,28-31,33H2,1-3H3,(H2-,45,46,47,48,49)/p+1/t41-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 2.70E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286368
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-naphthalen-2-y...)
Show SMILES O=C(Nc1cccnc1)[C@@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1
Show InChI InChI=1S/C31H39N5O/c37-30(33-28-16-9-19-32-22-28)29(21-23-17-18-24-10-7-8-11-25(24)20-23)36-31(34-26-12-3-1-4-13-26)35-27-14-5-2-6-15-27/h7-11,16-20,22,26-27,29H,1-6,12-15,21H2,(H,33,37)(H2,34,35,36)/p+1/t29-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 3.15E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286373
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-3-phenyl-N-[4-(t...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)\[#7]=[#6](\[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C41H65N4OP/c1-4-7-29-47(30-8-5-2,31-9-6-3)33-35-25-27-38(28-26-35)42-40(46)39(32-34-19-13-10-14-20-34)45-41(43-36-21-15-11-16-22-36)44-37-23-17-12-18-24-37/h10,13-14,19-20,25-28,36-37,39H,4-9,11-12,15-18,21-24,29-33H2,1-3H3,(H2-,42,43,44,45,46)/p+1/t39-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 3.25E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286377
PNG
(2,6-Bis-tripentylphosphanylmethyl-naphthalene; dic...)
Show SMILES CCCCC[P+](CCCCC)(CCCCC)Cc1ccc2cc(C[P+](CCCCC)(CCCCC)CCCCC)ccc2c1
Show InChI InChI=1S/C42H76P2/c1-7-13-19-29-43(30-20-14-8-2,31-21-15-9-3)37-39-25-27-42-36-40(26-28-41(42)35-39)38-44(32-22-16-10-4,33-23-17-11-5)34-24-18-12-6/h25-28,35-36H,7-24,29-34,37-38H2,1-6H3/q+2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
 3.30E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286386
PNG
(4,4'-Bis-(tripentyl-lambda*5*-phosphanylmethyl)-bi...)
Show SMILES CCCCC[P+](CCCCC)(CCCCC)Cc1ccc(cc1)-c1ccc(C[P+](CCCCC)(CCCCC)CCCCC)cc1
Show InChI InChI=1S/C44H78P2/c1-7-13-19-33-45(34-20-14-8-2,35-21-15-9-3)39-41-25-29-43(30-26-41)44-31-27-42(28-32-44)40-46(36-22-16-10-4,37-23-17-11-5)38-24-18-12-6/h25-32H,7-24,33-40H2,1-6H3/q+2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 3.40E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286385
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-2-naphthalen-2-y...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6](\[#7]=[#6](\[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C44H65N4OP/c1-4-7-30-50(31-8-5-2,32-9-6-3)34-35-24-28-41(29-25-35)45-43(49)42(38-27-26-36-18-16-17-19-37(36)33-38)48-44(46-39-20-12-10-13-21-39)47-40-22-14-11-15-23-40/h16-19,24-29,33,39-40,42H,4-15,20-23,30-32,34H2,1-3H3,(H2-,45,46,47,48,49)/p+1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 3.44E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286374
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-4-phenyl-N-[4-(t...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-c2ccccc2)\[#7]=[#6](/[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C42H67N4OP/c1-4-7-31-48(32-8-5-2,33-9-6-3)34-36-25-28-39(29-26-36)43-41(47)40(30-27-35-19-13-10-14-20-35)46-42(44-37-21-15-11-16-22-37)45-38-23-17-12-18-24-38/h10,13-14,19-20,25-26,28-29,37-38,40H,4-9,11-12,15-18,21-24,27,30-34H2,1-3H3,(H2-,43,44,45,46,47)/p+1/t40-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 4.65E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50289767
PNG
((S)-2-(N',N''-Dicyclohexyl-guanidino)-N-(4-hydroxy...)
Show SMILES [#8]-[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc3ccccc3c2)\[#7]=[#6](/[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1
Show InChI InChI=1S/C33H42N4O2/c38-23-24-16-19-30(20-17-24)34-32(39)31(22-25-15-18-26-9-7-8-10-27(26)21-25)37-33(35-28-11-3-1-4-12-28)36-29-13-5-2-6-14-29/h7-10,15-21,28-29,31,38H,1-6,11-14,22-23H2,(H,34,39)(H2,35,36,37)/t31-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 4.95E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286359
PNG
(N-(1H-Benzoimidazol-2-yl)-2-(N',N''-dicyclohexyl-g...)
Show SMILES O=C(Nc1nc2ccccc2[nH]1)[C@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1
Show InChI InChI=1S/C33H40N6O/c40-31(39-33-36-28-17-9-10-18-29(28)37-33)30(22-23-19-20-24-11-7-8-12-25(24)21-23)38-32(34-26-13-3-1-4-14-26)35-27-15-5-2-6-16-27/h7-12,17-21,26-27,30H,1-6,13-16,22H2,(H2,34,35,38)(H2,36,37,39,40)/p+1/t30-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
 5.30E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286380
PNG
(2-(N',N''-Diisopropyl-guanidino)-3-naphthalen-2-yl...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc3ccccc3c2)\[#7]=[#6](\[#7]-[#6](-[#6])-[#6])-[#7]-[#6](-[#6])-[#6])cc1 |r|
Show InChI InChI=1S/C39H59N4OP/c1-8-11-24-45(25-12-9-2,26-13-10-3)29-32-19-22-36(23-20-32)42-38(44)37(43-39(40-30(4)5)41-31(6)7)28-33-18-21-34-16-14-15-17-35(34)27-33/h14-23,27,30-31,37H,8-13,24-26,28-29H2,1-7H3,(H2-,40,41,42,43,44)/p+1/t37-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 7.05E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286384
PNG
(N-(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-2-(N...)
Show SMILES O=C(NC1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1)[C@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1 |wD:24.41,(14.19,-7.67,;14.04,-9.21,;15.29,-10.12,;16.83,-10.12,;17.59,-8.79,;18.92,-9.56,;17.82,-10.64,;19.16,-11.41,;19.9,-10.12,;19.13,-8.79,;17.59,-11.46,;17.58,-13,;16.25,-13.75,;14.92,-12.98,;13.57,-13.73,;13.56,-15.27,;14.9,-16.06,;16.23,-15.29,;18.92,-13.75,;20.25,-13,;21.58,-13.75,;21.58,-15.32,;20.23,-16.09,;18.9,-15.32,;12.63,-9.84,;12.46,-11.39,;11.36,-12.46,;12.14,-13.8,;11.39,-15.13,;9.84,-15.13,;9.1,-16.46,;7.56,-16.46,;6.78,-15.15,;7.55,-13.82,;9.07,-13.8,;9.83,-12.49,;11.37,-8.93,;9.87,-8.53,;8.78,-9.61,;7.23,-9.61,;6.48,-10.99,;4.75,-10.47,;3.58,-10.85,;4.47,-9.61,;5.92,-10.1,;9.48,-7.04,;7.98,-6.64,;6.66,-7.11,;5.22,-6.62,;4.33,-7.88,;5.49,-7.49,;7.22,-8.02,)|
Show InChI InChI=1S/C46H57N5O/c52-45(50-43-37-27-29-51(30-28-37)44(43)42(35-16-5-1-6-17-35)36-18-7-2-8-19-36)41(32-33-25-26-34-15-13-14-20-38(34)31-33)49-46(47-39-21-9-3-10-22-39)48-40-23-11-4-12-24-40/h1-2,5-8,13-20,25-26,31,37,39-44H,3-4,9-12,21-24,27-30,32H2,(H,50,52)(H2,47,48,49)/p+1/t41-,43?,44?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
 1.79E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286376
PNG
(4,4'-Bis-(tributyl-lambda*5*-phosphanylmethyl)-bip...)
Show SMILES CCCC[P+](CCCC)(CCCC)Cc1ccc(cc1)-c1ccc(C[P+](CCCC)(CCCC)CCCC)cc1
Show InChI InChI=1S/C38H66P2/c1-7-13-27-39(28-14-8-2,29-15-9-3)33-35-19-23-37(24-20-35)38-25-21-36(22-26-38)34-40(30-16-10-4,31-17-11-5)32-18-12-6/h19-26H,7-18,27-34H2,1-6H3/q+2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 2.07E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286363
PNG
(2-(N',N''-Diisopropyl-guanidino)-3-phenyl-N-[4-(tr...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)\[#7]=[#6](\[#7]-[#6](-[#6])-[#6])-[#7]-[#6](-[#6])-[#6])cc1 |r|
Show InChI InChI=1S/C35H57N4OP/c1-8-11-23-41(24-12-9-2,25-13-10-3)27-31-19-21-32(22-20-31)38-34(40)33(26-30-17-15-14-16-18-30)39-35(36-28(4)5)37-29(6)7/h14-22,28-29,33H,8-13,23-27H2,1-7H3,(H2-,36,37,38,39,40)/p+1/t33-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
 2.49E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286379
PNG
(4,4'-Bis-(tripropyl-lambda*5*-phosphanylmethyl)-bi...)
Show SMILES CCC[P+](CCC)(CCC)Cc1ccc(cc1)-c1ccc(C[P+](CCC)(CCC)CCC)cc1
Show InChI InChI=1S/C32H54P2/c1-7-21-33(22-8-2,23-9-3)27-29-13-17-31(18-14-29)32-19-15-30(16-20-32)28-34(24-10-4,25-11-5)26-12-6/h13-20H,7-12,21-28H2,1-6H3/q+2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
>2.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286362
PNG
(C-(4'-aminomethyl-biphenyl-4-yl)-methylamine | CHE...)
Show SMILES NCc1ccc(cc1)-c1ccc(CN)cc1
Show InChI InChI=1S/C14H16N2/c15-9-11-1-5-13(6-2-11)14-7-3-12(10-16)4-8-14/h1-8H,9-10,15-16H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents
Article
>2.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286360
PNG
(CHEMBL120746 | Dibutyl-(4'-tributylaminomethyl-bip...)
Show SMILES CCCC[N+](CCCC)(CCCC)Cc1ccc(cc1)-c1ccc(C[N+](CCCC)(CCCC)CCCC)cc1
Show InChI InChI=1S/C38H66N2/c1-7-13-27-39(28-14-8-2,29-15-9-3)33-35-19-23-37(24-20-35)38-25-21-36(22-26-38)34-40(30-16-10-4,31-17-11-5)32-18-12-6/h19-26H,7-18,27-34H2,1-6H3/q+2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
>2.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286358
PNG
(CHEMBL119082 | N-{(S)-2-Phenyl-1-[4-(tributyl-lamb...)
Show SMILES CCCC[P+](CCCC)(CCCC)Cc1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccc(C[P+](CCCC)(CCCC)CCCC)cc2)cc1
Show InChI InChI=1S/C48H74N2O2P2/c1-7-13-32-53(33-14-8-2,34-15-9-3)39-42-24-28-44(29-25-42)47(51)50-46(38-41-22-20-19-21-23-41)48(52)49-45-30-26-43(27-31-45)40-54(35-16-10-4,36-17-11-5)37-18-12-6/h19-31,46H,7-18,32-40H2,1-6H3/p+2/t46-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
>2.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286378
PNG
(N,N'-Dicyclohexyl-N''-[2-(4-methyl-piperazin-1-yl)...)
Show SMILES CN1CCN(CC1)C(=O)[C@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1
Show InChI InChI=1S/C31H45N5O/c1-35-18-20-36(21-19-35)30(37)29(23-24-16-17-25-10-8-9-11-26(25)22-24)34-31(32-27-12-4-2-5-13-27)33-28-14-6-3-7-15-28/h8-11,16-17,22,27-29H,2-7,12-15,18-21,23H2,1H3,(H2,32,33,34)/p+1/t29-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
>2.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286356
PNG
(2-(N',N''-Dicyclohexyl-guanidino)-4-methyl-pentano...)
Show SMILES [#6]-[#6]-[#6]-[#6][P+]([#6]-[#6]-[#6]-[#6])([#6]-[#6]-[#6]-[#6])[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])\[#7]=[#6](\[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |r|
Show InChI InChI=1S/C38H67N4OP/c1-6-9-26-44(27-10-7-2,28-11-8-3)30-32-22-24-35(25-23-32)39-37(43)36(29-31(4)5)42-38(40-33-18-14-12-15-19-33)41-34-20-16-13-17-21-34/h22-25,31,33-34,36H,6-21,26-30H2,1-5H3,(H2-,39,40,41,42,43)/p+1/t36-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
>1.00E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50286391
PNG
(2-(N',N''-Diisopropyl-guanidino)-N-[4-(tributyl-la...)
Show SMILES CCCC[P+](CCCC)(CCCC)Cc1ccc(NC(=O)CNC(NC(C)C)=NC(C)C)cc1 |w:28.28|
Show InChI InChI=1S/C28H51N4OP/c1-8-11-18-34(19-12-9-2,20-13-10-3)22-25-14-16-26(17-15-25)32-27(33)21-29-28(30-23(4)5)31-24(6)7/h14-17,23-24H,8-13,18-22H2,1-7H3,(H2-,29,30,31,32,33)/p+1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
>1.00E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Cavia porcellus)		BDBM50286387
PNG
(1,10-Bis-(tributyl-lambda*5*-phosphanyl)-decane; d...)
Show SMILES CCCC[P+](CCCC)(CCCC)CCCCCCCCCC[P+](CCCC)(CCCC)CCCC
Show InChI InChI=1S/C34H74P2/c1-7-13-27-35(28-14-8-2,29-15-9-3)33-25-23-21-19-20-22-24-26-34-36(30-16-10-4,31-17-11-5)32-18-12-6/h7-34H2,1-6H3/q+2
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a 3.90E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for competitive [3H]bradykinin binding to guinea pig ileum homogenates

Bioorg Med Chem Lett 5: 357-362 (1995)


Article DOI: 10.1016/0960-894X(95)00035-R
BindingDB Entry DOI: 10.7270/Q2S75GTM
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%