Found 18 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neprilysin
(Rattus norvegicus (Rat)) | BDBM50251742
((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)Show SMILES CC(C)C[C@H](NP(O)(=O)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C23H34N3O10P/c1-11(2)8-16(26-37(33,34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15/h4-7,10-12,16-20,23-24,27-29H,8-9H2,1-3H3,(H,25,30)(H,31,32)(H2,26,33,34)/t12-,16-,17-,18-,19+,20+,23-/m0/s1 | PDB
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| n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
compound was tested for inhibitory activity against neutral endopeptidase (NEP) |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287108
((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)Show SMILES CC(C)CC(CP(O)([O-])=C(Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C45H55N5O10PS/c1-30(2)23-36(42(51)48-40(44(53)54)26-35-27-47-38-18-10-9-17-37(35)38)29-61(56,57)41(25-32-20-21-33-15-7-8-16-34(33)24-32)49-43(52)39(50-62(3,58)59)19-11-12-22-46-45(55)60-28-31-13-5-4-6-14-31/h4-10,13-18,20-21,24,27,30,36,39-40,47,50H,11-12,19,22-23,25-26,28-29H2,1-3H3,(H5-,46,48,49,51,52,53,54,55,56,57)/q-1/p-1/t36?,39-,40-/m0/s1 | PDB
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| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287103
((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)Show SMILES CC(C)CC(CP(O)([O-])=C(CC(C)C)NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C38H55N5O10PS/c1-25(2)19-29(35(44)41-33(37(46)47)21-28-22-40-31-16-10-9-15-30(28)31)24-54(49,50)34(20-26(3)4)42-36(45)32(43-55(5,51)52)17-11-12-18-39-38(48)53-23-27-13-7-6-8-14-27/h6-10,13-16,22,25-26,29,32-33,40,43H,11-12,17-21,23-24H2,1-5H3,(H5-,39,41,42,44,45,46,47,48,49,50)/q-1/p-1/t29?,32-,33-/m0/s1 | PDB
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| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287107
((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)Show SMILES CC(C)CC(CP(O)([O-])=C(Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCCN)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C37H49N5O8PS/c1-24(2)18-29(35(43)40-33(37(45)46)21-28-22-39-31-13-7-6-12-30(28)31)23-51(47,48)34(20-25-15-16-26-10-4-5-11-27(26)19-25)41-36(44)32(14-8-9-17-38)42-52(3,49)50/h4-7,10-13,15-16,19,22,24,29,32-33,39,42H,8-9,14,17-18,20-21,23,38H2,1-3H3,(H4-,40,41,43,44,45,46,47,48)/q-1/p-1/t29?,32-,33-/m0/s1 | PDB
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| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50251742
((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)Show SMILES CC(C)C[C@H](NP(O)(=O)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C23H34N3O10P/c1-11(2)8-16(26-37(33,34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15/h4-7,10-12,16-20,23-24,27-29H,8-9H2,1-3H3,(H,25,30)(H,31,32)(H2,26,33,34)/t12-,16-,17-,18-,19+,20+,23-/m0/s1 | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287102
((S)-2-(2-{[1-((S)-2-Benzyloxycarbonylamino-4-methy...)Show SMILES CC(C)CC(CP(O)([O-])=C(Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C40H50N4O8P/c1-26(2)19-31(37(45)42-35(39(47)48)22-30-23-41-33-18-12-11-17-32(30)33)25-53(50,51)36(21-28-13-7-5-8-14-28)44-38(46)34(20-27(3)4)43-40(49)52-24-29-15-9-6-10-16-29/h5-18,23,26-27,31,34-35,41H,19-22,24-25H2,1-4H3,(H5-,42,43,44,45,46,47,48,49,50,51)/q-1/p-1/t31?,34-,35-/m0/s1 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287111
((S)-2-(2-{[1-((S)-6-Amino-2-benzyloxycarbonylamino...)Show SMILES CC(C)C(CP(O)([O-])=C(Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C39H49N5O8P/c1-26(2)31(36(45)42-34(38(47)48)22-29-23-41-32-18-10-9-17-30(29)32)25-53(50,51)35(21-27-13-5-3-6-14-27)44-37(46)33(19-11-12-20-40)43-39(49)52-24-28-15-7-4-8-16-28/h3-10,13-18,23,26,31,33-34,41H,11-12,19-22,24-25,40H2,1-2H3,(H5-,42,43,44,45,46,47,48,49,50,51)/q-1/p-1/t31?,33-,34-/m0/s1 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Neprilysin
(Rattus norvegicus (Rat)) | BDBM50287103
((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)Show SMILES CC(C)CC(CP(O)([O-])=C(CC(C)C)NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C38H55N5O10PS/c1-25(2)19-29(35(44)41-33(37(46)47)21-28-22-40-31-16-10-9-15-30(28)31)24-54(49,50)34(20-26(3)4)42-36(45)32(43-55(5,51)52)17-11-12-18-39-38(48)53-23-27-13-7-6-8-14-27/h6-10,13-16,22,25-26,29,32-33,40,43H,11-12,17-21,23-24H2,1-5H3,(H5-,39,41,42,44,45,46,47,48,49,50)/q-1/p-1/t29?,32-,33-/m0/s1 | PDB
MMDB
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| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
compound was tested for inhibitory activity against neutral endopeptidase (NEP) |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Neprilysin
(Rattus norvegicus (Rat)) | BDBM50287099
((S)-2-(3-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)Show SMILES CC(C)CC(NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NS(C)(=O)=O)=P(O)([O-])CC(C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C35H49N5O10PS/c1-23(2)18-31(39-33(42)29(40-52(4,48)49)16-10-11-17-36-35(45)50-21-25-12-6-5-7-13-25)51(46,47)22-24(3)32(41)38-30(34(43)44)19-26-20-37-28-15-9-8-14-27(26)28/h5-9,12-15,20,23-24,29-30,37,40H,10-11,16-19,21-22H2,1-4H3,(H5-,36,38,39,41,42,43,44,45,46,47)/q-1/p-1/t24?,29-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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| Article
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for inhibitory activity against neutral endopeptidase (NEP) |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287110
((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)Show SMILES CC(C)C(CP(O)([O-])=C(Cc1ccccc1)NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C40H51N5O10PS/c1-27(2)32(37(46)43-35(39(48)49)23-30-24-42-33-19-11-10-18-31(30)33)26-56(51,52)36(22-28-14-6-4-7-15-28)44-38(47)34(45-57(3,53)54)20-12-13-21-41-40(50)55-25-29-16-8-5-9-17-29/h4-11,14-19,24,27,32,34-35,42,45H,12-13,20-23,25-26H2,1-3H3,(H5-,41,43,44,46,47,48,49,50,51,52)/q-1/p-1/t32?,34-,35-/m0/s1 | PDB
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| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287100
((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)Show SMILES CC(C)CC(CP(O)([O-])=C(Cc1ccccc1)NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C41H53N5O10PS/c1-28(2)22-32(38(47)44-36(40(49)50)24-31-25-43-34-19-11-10-18-33(31)34)27-57(52,53)37(23-29-14-6-4-7-15-29)45-39(48)35(46-58(3,54)55)20-12-13-21-42-41(51)56-26-30-16-8-5-9-17-30/h4-11,14-19,25,28,32,35-36,43,46H,12-13,20-24,26-27H2,1-3H3,(H5-,42,44,45,47,48,49,50,51,52,53)/q-1/p-1/t32?,35-,36-/m0/s1 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287101
((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)Show SMILES CC(C)C(CP(O)([O-])=C(Cc1ccccc1)NC(=O)[C@H](CCCCN)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C32H45N5O8PS/c1-21(2)25(30(38)35-28(32(40)41)18-23-19-34-26-14-8-7-13-24(23)26)20-46(42,43)29(17-22-11-5-4-6-12-22)36-31(39)27(15-9-10-16-33)37-47(3,44)45/h4-8,11-14,19,21,25,27-28,34,37H,9-10,15-18,20,33H2,1-3H3,(H4-,35,36,38,39,40,41,42,43)/q-1/p-1/t25?,27-,28-/m0/s1 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Neprilysin
(Rattus norvegicus (Rat)) | BDBM50287101
((S)-2-(2-{[1-((S)-6-Amino-2-methanesulfonylamino-h...)Show SMILES CC(C)C(CP(O)([O-])=C(Cc1ccccc1)NC(=O)[C@H](CCCCN)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C32H45N5O8PS/c1-21(2)25(30(38)35-28(32(40)41)18-23-19-34-26-14-8-7-13-24(23)26)20-46(42,43)29(17-22-11-5-4-6-12-22)36-31(39)27(15-9-10-16-33)37-47(3,44)45/h4-8,11-14,19,21,25,27-28,34,37H,9-10,15-18,20,33H2,1-3H3,(H4-,35,36,38,39,40,41,42,43)/q-1/p-1/t25?,27-,28-/m0/s1 | PDB
MMDB
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| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
compound was tested for inhibitory activity against neutral endopeptidase (NEP) |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287105
((S)-2-(2-{[1-((S)-6-Benzyloxycarbonylamino-2-metha...)Show SMILES CC(C)C(CP(O)([O-])=C(Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NS(C)(=O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C44H53N5O10PS/c1-29(2)36(41(50)47-39(43(52)53)25-34-26-46-37-18-10-9-17-35(34)37)28-60(55,56)40(24-31-20-21-32-15-7-8-16-33(32)23-31)48-42(51)38(49-61(3,57)58)19-11-12-22-45-44(54)59-27-30-13-5-4-6-14-30/h4-10,13-18,20-21,23,26,29,36,38-39,46,49H,11-12,19,22,24-25,27-28H2,1-3H3,(H5-,45,47,48,50,51,52,53,54,55,56)/q-1/p-1/t36?,38-,39-/m0/s1 | PDB
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| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287106
((S)-2-{2-[(1-Benzyloxycarbonylamino-2-naphthalen-2...)Show SMILES CC(C)CC(CP(O)([O-])=C(Cc1ccc2ccccc2c1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C38H41N3O7P/c1-25(2)18-31(36(42)40-34(37(43)44)21-30-22-39-33-15-9-8-14-32(30)33)24-49(46,47)35(41-38(45)48-23-26-10-4-3-5-11-26)20-27-16-17-28-12-6-7-13-29(28)19-27/h3-17,19,22,25,31,34,39H,18,20-21,23-24H2,1-2H3,(H4-,40,41,42,43,44,45,46,47)/q-1/p-1/t31?,34-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for inhibitory activity against Endothelin-converting enzyme isolated from guinea pig lung membrane. |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287109
((S)-2-{2-[(1-Benzyloxycarbonylamino-2-methyl-propy...)Show SMILES CC(C)C(CP(O)([O-])=C(NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C29H37N3O7P/c1-18(2)23(26(33)31-25(28(34)35)14-21-15-30-24-13-9-8-12-22(21)24)17-40(37,38)27(19(3)4)32-29(36)39-16-20-10-6-5-7-11-20/h5-13,15,18-19,23,25,30H,14,16-17H2,1-4H3,(H4-,31,32,33,34,35,36,37,38)/q-1/p-1/t23?,25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287104
((S)-2-{2-[(1-Benzyloxycarbonylamino-2-phenyl-ethyl...)Show SMILES CC(C)C(CP(O)([O-])=C(Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C33H37N3O7P/c1-22(2)27(31(37)35-29(32(38)39)18-25-19-34-28-16-10-9-15-26(25)28)21-44(41,42)30(17-23-11-5-3-6-12-23)36-33(40)43-20-24-13-7-4-8-14-24/h3-16,19,22,27,29,34H,17-18,20-21H2,1-2H3,(H4-,35,36,37,38,39,40,41,42)/q-1/p-1/t27?,29-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287104
((S)-2-{2-[(1-Benzyloxycarbonylamino-2-phenyl-ethyl...)Show SMILES CC(C)C(CP(O)([O-])=C(Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O Show InChI InChI=1S/C33H37N3O7P/c1-22(2)27(31(37)35-29(32(38)39)18-25-19-34-28-16-10-9-15-26(25)28)21-44(41,42)30(17-23-11-5-3-6-12-23)36-33(40)43-20-24-13-7-4-8-14-24/h3-16,19,22,27,29,34H,17-18,20-21H2,1-2H3,(H4-,35,36,37,38,39,40,41,42)/q-1/p-1/t27?,29-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Endothelin-converting enzyme of guinea pig lung membrane |
Bioorg Med Chem Lett 6: 1257-1260 (1996)
Article DOI: 10.1016/0960-894X(96)00211-9
BindingDB Entry DOI: 10.7270/Q2ZS2X1M |
More data for this
Ligand-Target Pair | |
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