Found 65 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neprilysin
(Homo sapiens (Human)) | BDBM50287140
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C29H33N2O7P/c1-21(28(33)34)30-27(32)25(17-22-11-5-2-6-12-22)20-39(36,37)26(18-23-13-7-3-8-14-23)31-29(35)38-19-24-15-9-4-10-16-24/h2-16,21,25-26H,17-20H2,1H3,(H,30,32)(H,31,35)(H,33,34)(H,36,37)/t21?,25?,26-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287137
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CCCCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-2-3-19-28(31(36)37)33-30(35)27(20-24-13-7-4-8-14-24)23-42(39,40)29(21-25-15-9-5-10-16-25)34-32(38)41-22-26-17-11-6-12-18-26/h4-18,27-29H,2-3,19-23H2,1H3,(H,33,35)(H,34,38)(H,36,37)(H,39,40)/t27?,28?,29-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287138
(2-[(2-{[hydroxy(4-phenyl-butyl)phosphoryl]amino}-3...)Show SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NP(O)(=O)CCCCc1ccccc1 Show InChI InChI=1S/C30H34N3O5P/c34-29(32-28(30(35)36)20-24-21-31-26-17-8-7-16-25(24)26)27(19-23-14-5-2-6-15-23)33-39(37,38)18-10-9-13-22-11-3-1-4-12-22/h1-8,11-12,14-17,21,27-28,31H,9-10,13,18-20H2,(H,32,34)(H,35,36)(H2,33,37,38)/t27-,28-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50251742
((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)Show SMILES CC(C)C[C@H](NP(O)(=O)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C23H34N3O10P/c1-11(2)8-16(26-37(33,34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15/h4-7,10-12,16-20,23-24,27-29H,8-9H2,1-3H3,(H,25,30)(H,31,32)(H2,26,33,34)/t12-,16-,17-,18-,19+,20+,23-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Neprilysin
(Homo sapiens (Human)) | BDBM50287134
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O7P/c38-33(36-31(34(39)40)22-27-15-7-2-8-16-27)30(21-26-13-5-1-6-14-26)25-45(42,43)32(23-28-17-9-3-10-18-28)37-35(41)44-24-29-19-11-4-12-20-29/h1-20,30-32H,21-25H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)/t30?,31?,32-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287136
(2-{(R)-2-Benzyl-3-[(1-benzyloxycarbonylamino-2-phe...)Show SMILES NC(=N)NCCCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H40N5O7P/c33-31(34)35-18-10-17-27(30(39)40)36-29(38)26(19-23-11-4-1-5-12-23)22-45(42,43)28(20-24-13-6-2-7-14-24)37-32(41)44-21-25-15-8-3-9-16-25/h1-9,11-16,26-28H,10,17-22H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)(H4,33,34,35)/t26?,27?,28-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287129
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H33N2O9P/c33-27(34)18-25(29(36)37)31-28(35)24(16-21-10-4-1-5-11-21)20-42(39,40)26(17-22-12-6-2-7-13-22)32-30(38)41-19-23-14-8-3-9-15-23/h1-15,24-26H,16-20H2,(H,31,35)(H,32,38)(H,33,34)(H,36,37)(H,39,40)/t24?,25?,26-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287147
(CHEMBL282158 | {2-Benzyl-3-[((R)-1-benzyloxycarbon...)Show SMILES OC(=O)CNC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C28H31N2O7P/c31-26(32)18-29-27(33)24(16-21-10-4-1-5-11-21)20-38(35,36)25(17-22-12-6-2-7-13-22)30-28(34)37-19-23-14-8-3-9-15-23/h1-15,24-25H,16-20H2,(H,29,33)(H,30,34)(H,31,32)(H,35,36)/t24?,25-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287130
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C37H38N3O7P/c41-35(39-33(36(42)43)22-29-23-38-32-19-11-10-18-31(29)32)30(20-26-12-4-1-5-13-26)25-48(45,46)34(21-27-14-6-2-7-15-27)40-37(44)47-24-28-16-8-3-9-17-28/h1-19,23,30,33-34,38H,20-22,24-25H2,(H,39,41)(H,40,44)(H,42,43)(H,45,46)/t30?,33?,34-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287130
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C37H38N3O7P/c41-35(39-33(36(42)43)22-29-23-38-32-19-11-10-18-31(29)32)30(20-26-12-4-1-5-13-26)25-48(45,46)34(21-27-14-6-2-7-15-27)40-37(44)47-24-28-16-8-3-9-17-28/h1-19,23,30,33-34,38H,20-22,24-25H2,(H,39,41)(H,40,44)(H,42,43)(H,45,46)/t30?,33?,34-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287150
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CCC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-3-23(2)29(31(36)37)34-30(35)27(19-24-13-7-4-8-14-24)22-42(39,40)28(20-25-15-9-5-10-16-25)33-32(38)41-21-26-17-11-6-12-18-26/h4-18,23,27-29H,3,19-22H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)(H,39,40)/t23?,27?,28-,29?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287130
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C37H38N3O7P/c41-35(39-33(36(42)43)22-29-23-38-32-19-11-10-18-31(29)32)30(20-26-12-4-1-5-13-26)25-48(45,46)34(21-27-14-6-2-7-15-27)40-37(44)47-24-28-16-8-3-9-17-28/h1-19,23,30,33-34,38H,20-22,24-25H2,(H,39,41)(H,40,44)(H,42,43)(H,45,46)/t30?,33?,34-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287130
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C37H38N3O7P/c41-35(39-33(36(42)43)22-29-23-38-32-19-11-10-18-31(29)32)30(20-26-12-4-1-5-13-26)25-48(45,46)34(21-27-14-6-2-7-15-27)40-37(44)47-24-28-16-8-3-9-17-28/h1-19,23,30,33-34,38H,20-22,24-25H2,(H,39,41)(H,40,44)(H,42,43)(H,45,46)/t30?,33?,34-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287141
(3-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)CCNC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C29H33N2O7P/c32-27(33)16-17-30-28(34)25(18-22-10-4-1-5-11-22)21-39(36,37)26(19-23-12-6-2-7-13-23)31-29(35)38-20-24-14-8-3-9-15-24/h1-15,25-26H,16-21H2,(H,30,34)(H,31,35)(H,32,33)(H,36,37)/t25?,26-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287139
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O8P/c38-30-18-16-27(17-19-30)21-31(34(40)41)36-33(39)29(20-25-10-4-1-5-11-25)24-46(43,44)32(22-26-12-6-2-7-13-26)37-35(42)45-23-28-14-8-3-9-15-28/h1-19,29,31-32,38H,20-24H2,(H,36,39)(H,37,42)(H,40,41)(H,43,44)/t29?,31?,32-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287139
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O8P/c38-30-18-16-27(17-19-30)21-31(34(40)41)36-33(39)29(20-25-10-4-1-5-11-25)24-46(43,44)32(22-26-12-6-2-7-13-26)37-35(42)45-23-28-14-8-3-9-15-28/h1-19,29,31-32,38H,20-24H2,(H,36,39)(H,37,42)(H,40,41)(H,43,44)/t29?,31?,32-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50213993
(CHEMBL25154)Show SMILES OC(=O)CCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H35N2O9P/c34-28(35)17-16-26(30(37)38)32-29(36)25(18-22-10-4-1-5-11-22)21-43(40,41)27(19-23-12-6-2-7-13-23)33-31(39)42-20-24-14-8-3-9-15-24/h1-15,25-27H,16-21H2,(H,32,36)(H,33,39)(H,34,35)(H,37,38)(H,40,41)/t25?,26?,27-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287131
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H37N2O7P/c1-22(2)28(30(35)36)33-29(34)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)32-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/t26?,27-,28?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287150
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CCC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-3-23(2)29(31(36)37)34-30(35)27(19-24-13-7-4-8-14-24)22-42(39,40)28(20-25-15-9-5-10-16-25)33-32(38)41-21-26-17-11-6-12-18-26/h4-18,23,27-29H,3,19-22H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)(H,39,40)/t23?,27?,28-,29?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287136
(2-{(R)-2-Benzyl-3-[(1-benzyloxycarbonylamino-2-phe...)Show SMILES NC(=N)NCCCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H40N5O7P/c33-31(34)35-18-10-17-27(30(39)40)36-29(38)26(19-23-11-4-1-5-12-23)22-45(42,43)28(20-24-13-6-2-7-14-24)37-32(41)44-21-25-15-8-3-9-16-25/h1-9,11-16,26-28H,10,17-22H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)(H4,33,34,35)/t26?,27?,28-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287151
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES CC(O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21?,25?,26-,27-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287133
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES NC(=O)CCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H36N3O8P/c32-27(35)17-16-26(30(37)38)33-29(36)25(18-22-10-4-1-5-11-22)21-43(40,41)28(19-23-12-6-2-7-13-23)34-31(39)42-20-24-14-8-3-9-15-24/h1-15,25-26,28H,16-21H2,(H2,32,35)(H,33,36)(H,34,39)(H,37,38)(H,40,41)/t25?,26?,28-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287142
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-23(2)18-28(31(36)37)33-30(35)27(19-24-12-6-3-7-13-24)22-42(39,40)29(20-25-14-8-4-9-15-25)34-32(38)41-21-26-16-10-5-11-17-26/h3-17,23,27-29H,18-22H2,1-2H3,(H,33,35)(H,34,38)(H,36,37)(H,39,40)/t27?,28?,29-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287142
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-23(2)18-28(31(36)37)33-30(35)27(19-24-12-6-3-7-13-24)22-42(39,40)29(20-25-14-8-4-9-15-25)34-32(38)41-21-26-16-10-5-11-17-26/h3-17,23,27-29H,18-22H2,1-2H3,(H,33,35)(H,34,38)(H,36,37)(H,39,40)/t27?,28?,29-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287140
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C29H33N2O7P/c1-21(28(33)34)30-27(32)25(17-22-11-5-2-6-12-22)20-39(36,37)26(18-23-13-7-3-8-14-23)31-29(35)38-19-24-15-9-4-10-16-24/h2-16,21,25-26H,17-20H2,1H3,(H,30,32)(H,31,35)(H,33,34)(H,36,37)/t21?,25?,26-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287144
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES NC(=O)CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H34N3O8P/c31-26(34)18-25(29(36)37)32-28(35)24(16-21-10-4-1-5-11-21)20-42(39,40)27(17-22-12-6-2-7-13-22)33-30(38)41-19-23-14-8-3-9-15-23/h1-15,24-25,27H,16-20H2,(H2,31,34)(H,32,35)(H,33,38)(H,36,37)(H,39,40)/t24?,25?,27-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287151
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES CC(O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21?,25?,26-,27-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287134
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O7P/c38-33(36-31(34(39)40)22-27-15-7-2-8-16-27)30(21-26-13-5-1-6-14-26)25-45(42,43)32(23-28-17-9-3-10-18-28)37-35(41)44-24-29-19-11-4-12-20-29/h1-20,30-32H,21-25H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)/t30?,31?,32-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287148
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1cnc[nH]1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C32H35N4O7P/c37-30(35-28(31(38)39)18-27-19-33-22-34-27)26(16-23-10-4-1-5-11-23)21-44(41,42)29(17-24-12-6-2-7-13-24)36-32(40)43-20-25-14-8-3-9-15-25/h1-15,19,22,26,28-29H,16-18,20-21H2,(H,33,34)(H,35,37)(H,36,40)(H,38,39)(H,41,42)/t26?,28?,29-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287137
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CCCCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-2-3-19-28(31(36)37)33-30(35)27(20-24-13-7-4-8-14-24)23-42(39,40)29(21-25-15-9-5-10-16-25)34-32(38)41-22-26-17-11-6-12-18-26/h4-18,27-29H,2-3,19-23H2,1H3,(H,33,35)(H,34,38)(H,36,37)(H,39,40)/t27?,28?,29-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287139
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O8P/c38-30-18-16-27(17-19-30)21-31(34(40)41)36-33(39)29(20-25-10-4-1-5-11-25)24-46(43,44)32(22-26-12-6-2-7-13-26)37-35(42)45-23-28-14-8-3-9-15-28/h1-19,29,31-32,38H,20-24H2,(H,36,39)(H,37,42)(H,40,41)(H,43,44)/t29?,31?,32-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287139
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O8P/c38-30-18-16-27(17-19-30)21-31(34(40)41)36-33(39)29(20-25-10-4-1-5-11-25)24-46(43,44)32(22-26-12-6-2-7-13-26)37-35(42)45-23-28-14-8-3-9-15-28/h1-19,29,31-32,38H,20-24H2,(H,36,39)(H,37,42)(H,40,41)(H,43,44)/t29?,31?,32-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287133
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES NC(=O)CCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H36N3O8P/c32-27(35)17-16-26(30(37)38)33-29(36)25(18-22-10-4-1-5-11-22)21-43(40,41)28(19-23-12-6-2-7-13-23)34-31(39)42-20-24-14-8-3-9-15-24/h1-15,25-26,28H,16-21H2,(H2,32,35)(H,33,36)(H,34,39)(H,37,38)(H,40,41)/t25?,26?,28-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287148
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)C(Cc1cnc[nH]1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C32H35N4O7P/c37-30(35-28(31(38)39)18-27-19-33-22-34-27)26(16-23-10-4-1-5-11-23)21-44(41,42)29(17-24-12-6-2-7-13-24)36-32(40)43-20-25-14-8-3-9-15-25/h1-15,19,22,26,28-29H,16-18,20-21H2,(H,33,34)(H,35,37)(H,36,40)(H,38,39)(H,41,42)/t26?,28?,29-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287132
(((R)-1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-(...)Show SMILES CC(C)[C@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(N)=O Show InChI InChI=1S/C31H38N3O6P/c1-22(2)28(29(32)35)34-30(36)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)33-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H2,32,35)(H,33,37)(H,34,36)(H,38,39)/t26?,27-,28+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287144
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES NC(=O)CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H34N3O8P/c31-26(34)18-25(29(36)37)32-28(35)24(16-21-10-4-1-5-11-21)20-42(39,40)27(17-22-12-6-2-7-13-22)33-30(38)41-19-23-14-8-3-9-15-23/h1-15,24-25,27H,16-20H2,(H2,31,34)(H,32,35)(H,33,38)(H,36,37)(H,39,40)/t24?,25?,27-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287142
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-23(2)18-28(31(36)37)33-30(35)27(19-24-12-6-3-7-13-24)22-42(39,40)29(20-25-14-8-4-9-15-25)34-32(38)41-21-26-16-10-5-11-17-26/h3-17,23,27-29H,18-22H2,1-2H3,(H,33,35)(H,34,38)(H,36,37)(H,39,40)/t27?,28?,29-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287142
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-23(2)18-28(31(36)37)33-30(35)27(19-24-12-6-3-7-13-24)22-42(39,40)29(20-25-14-8-4-9-15-25)34-32(38)41-21-26-16-10-5-11-17-26/h3-17,23,27-29H,18-22H2,1-2H3,(H,33,35)(H,34,38)(H,36,37)(H,39,40)/t27?,28?,29-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50213993
(CHEMBL25154)Show SMILES OC(=O)CCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H35N2O9P/c34-28(35)17-16-26(30(37)38)32-29(36)25(18-22-10-4-1-5-11-22)21-43(40,41)27(19-23-12-6-2-7-13-23)33-31(39)42-20-24-14-8-3-9-15-24/h1-15,25-27H,16-21H2,(H,32,36)(H,33,39)(H,34,35)(H,37,38)(H,40,41)/t25?,26?,27-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287129
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)CC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H33N2O9P/c33-27(34)18-25(29(36)37)31-28(35)24(16-21-10-4-1-5-11-21)20-42(39,40)26(17-22-12-6-2-7-13-22)32-30(38)41-19-23-14-8-3-9-15-23/h1-15,24-26H,16-20H2,(H,31,35)(H,32,38)(H,33,34)(H,36,37)(H,39,40)/t24?,25?,26-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287143
(6-Amino-2-{2-benzyl-3-[((R)-1-benzyloxycarbonylami...)Show SMILES NCCCCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H40N3O7P/c33-19-11-10-18-28(31(37)38)34-30(36)27(20-24-12-4-1-5-13-24)23-43(40,41)29(21-25-14-6-2-7-15-25)35-32(39)42-22-26-16-8-3-9-17-26/h1-9,12-17,27-29H,10-11,18-23,33H2,(H,34,36)(H,35,39)(H,37,38)(H,40,41)/t27?,28?,29-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287143
(6-Amino-2-{2-benzyl-3-[((R)-1-benzyloxycarbonylami...)Show SMILES NCCCCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H40N3O7P/c33-19-11-10-18-28(31(37)38)34-30(36)27(20-24-12-4-1-5-13-24)23-43(40,41)29(21-25-14-6-2-7-15-25)35-32(39)42-22-26-16-8-3-9-17-26/h1-9,12-17,27-29H,10-11,18-23,33H2,(H,34,36)(H,35,39)(H,37,38)(H,40,41)/t27?,28?,29-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287141
(3-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES OC(=O)CCNC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C29H33N2O7P/c32-27(33)16-17-30-28(34)25(18-22-10-4-1-5-11-22)21-39(36,37)26(19-23-12-6-2-7-13-23)31-29(35)38-20-24-14-8-3-9-15-24/h1-15,25-26H,16-21H2,(H,30,34)(H,31,35)(H,32,33)(H,36,37)/t25?,26-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50366431
(CHEMBL1794047)Show SMILES C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21-,25?,26+,27+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287135
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES CC(C)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H37N2O7P/c1-22(2)28(30(35)36)33-29(34)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)32-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/t26?,27-,28-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287135
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES CC(C)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H37N2O7P/c1-22(2)28(30(35)36)33-29(34)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)32-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/t26?,27-,28-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287145
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O7P/c38-33(36-31(34(39)40)22-27-15-7-2-8-16-27)30(21-26-13-5-1-6-14-26)25-45(42,43)32(23-28-17-9-3-10-18-28)37-35(41)44-24-29-19-11-4-12-20-29/h1-20,30-32H,21-25H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)/t30?,31-,32-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287135
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES CC(C)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H37N2O7P/c1-22(2)28(30(35)36)33-29(34)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)32-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/t26?,27-,28-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287146
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H40N5O7P/c33-31(34)35-18-10-17-27(30(39)40)36-29(38)26(19-23-11-4-1-5-12-23)22-45(42,43)28(20-24-13-6-2-7-14-24)37-32(41)44-21-25-15-8-3-9-16-25/h1-9,11-16,26-28H,10,17-22H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)(H4,33,34,35)/t26?,27-,28-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287131
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H37N2O7P/c1-22(2)28(30(35)36)33-29(34)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)32-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/t26?,27-,28?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287147
(CHEMBL282158 | {2-Benzyl-3-[((R)-1-benzyloxycarbon...)Show SMILES OC(=O)CNC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C28H31N2O7P/c31-26(32)18-29-27(33)24(16-21-10-4-1-5-11-21)20-38(35,36)25(17-22-12-6-2-7-13-22)30-28(34)37-19-23-14-8-3-9-15-23/h1-15,24-25H,16-20H2,(H,29,33)(H,30,34)(H,31,32)(H,35,36)/t24?,25-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287131
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H37N2O7P/c1-22(2)28(30(35)36)33-29(34)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)32-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/t26?,27-,28?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287135
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES CC(C)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H37N2O7P/c1-22(2)28(30(35)36)33-29(34)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)32-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/t26?,27-,28-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50366431
(CHEMBL1794047)Show SMILES C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21-,25?,26+,27+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50366431
(CHEMBL1794047)Show SMILES C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21-,25?,26+,27+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287143
(6-Amino-2-{2-benzyl-3-[((R)-1-benzyloxycarbonylami...)Show SMILES NCCCCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H40N3O7P/c33-19-11-10-18-28(31(37)38)34-30(36)27(20-24-12-4-1-5-13-24)23-43(40,41)29(21-25-14-6-2-7-15-25)35-32(39)42-22-26-16-8-3-9-17-26/h1-9,12-17,27-29H,10-11,18-23,33H2,(H,34,36)(H,35,39)(H,37,38)(H,40,41)/t27?,28?,29-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287145
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O7P/c38-33(36-31(34(39)40)22-27-15-7-2-8-16-27)30(21-26-13-5-1-6-14-26)25-45(42,43)32(23-28-17-9-3-10-18-28)37-35(41)44-24-29-19-11-4-12-20-29/h1-20,30-32H,21-25H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)/t30?,31-,32-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287149
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES OC(=O)CC[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H35N2O9P/c34-28(35)17-16-26(30(37)38)32-29(36)25(18-22-10-4-1-5-11-22)21-43(40,41)27(19-23-12-6-2-7-13-23)33-31(39)42-20-24-14-8-3-9-15-24/h1-15,25-27H,16-21H2,(H,32,36)(H,33,39)(H,34,35)(H,37,38)(H,40,41)/t25?,26-,27-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287133
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES NC(=O)CCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H36N3O8P/c32-27(35)17-16-26(30(37)38)33-29(36)25(18-22-10-4-1-5-11-22)21-43(40,41)28(19-23-12-6-2-7-13-23)34-31(39)42-20-24-14-8-3-9-15-24/h1-15,25-26,28H,16-21H2,(H2,32,35)(H,33,36)(H,34,39)(H,37,38)(H,40,41)/t25?,26?,28-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287146
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H40N5O7P/c33-31(34)35-18-10-17-27(30(39)40)36-29(38)26(19-23-11-4-1-5-12-23)22-45(42,43)28(20-24-13-6-2-7-14-24)37-32(41)44-21-25-15-8-3-9-16-25/h1-9,11-16,26-28H,10,17-22H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)(H4,33,34,35)/t26?,27-,28-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287149
((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...)Show SMILES OC(=O)CC[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H35N2O9P/c34-28(35)17-16-26(30(37)38)32-29(36)25(18-22-10-4-1-5-11-22)21-43(40,41)27(19-23-12-6-2-7-13-23)33-31(39)42-20-24-14-8-3-9-15-24/h1-15,25-27H,16-21H2,(H,32,36)(H,33,39)(H,34,35)(H,37,38)(H,40,41)/t25?,26-,27-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287143
(6-Amino-2-{2-benzyl-3-[((R)-1-benzyloxycarbonylami...)Show SMILES NCCCCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H40N3O7P/c33-19-11-10-18-28(31(37)38)34-30(36)27(20-24-12-4-1-5-13-24)23-43(40,41)29(21-25-14-6-2-7-15-25)35-32(39)42-22-26-16-8-3-9-17-26/h1-9,12-17,27-29H,10-11,18-23,33H2,(H,34,36)(H,35,39)(H,37,38)(H,40,41)/t27?,28?,29-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50287133
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES NC(=O)CCC(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H36N3O8P/c32-27(35)17-16-26(30(37)38)33-29(36)25(18-22-10-4-1-5-11-22)21-43(40,41)28(19-23-12-6-2-7-13-23)34-31(39)42-20-24-14-8-3-9-15-24/h1-15,25-26,28H,16-21H2,(H2,32,35)(H,33,36)(H,34,39)(H,37,38)(H,40,41)/t25?,26?,28-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50366431
(CHEMBL1794047)Show SMILES C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21-,25?,26+,27+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Neprilysin
(Homo sapiens (Human)) | BDBM50287131
(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)Show SMILES CC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C31H37N2O7P/c1-22(2)28(30(35)36)33-29(34)26(18-23-12-6-3-7-13-23)21-41(38,39)27(19-24-14-8-4-9-15-24)32-31(37)40-20-25-16-10-5-11-17-25/h3-17,22,26-28H,18-21H2,1-2H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/t26?,27-,28?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of neutral endopeptidase in human umbilical vein endothelial cells |
Bioorg Med Chem Lett 6: 1323-1326 (1996)
Article DOI: 10.1016/0960-894X(96)00227-2
BindingDB Entry DOI: 10.7270/Q2Q81DKV |
More data for this
Ligand-Target Pair | |
Search and Browse
