Found 18 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM21392
(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-HT1A receptor by displacing [3H]8-OH-DPAT from pig cortex |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM21392
(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 1D receptor by displacing [125I]GTI from pig caudate |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50421346
(CHEMBL19114)Show InChI InChI=1S/C11H12N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5-6H,3-4,12H2,(H2,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-HT1A receptor by displacing [3H]8-OH-DPAT from pig cortex |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50421348
(CHEMBL18710)Show InChI InChI=1S/C13H16N2O2/c1-15(2)6-5-10-8-17-12-4-3-9(13(14)16)7-11(10)12/h3-4,7-8H,5-6H2,1-2H3,(H2,14,16) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-HT1A receptor by displacing [3H]8-OH-DPAT from pig cortex |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50421346
(CHEMBL19114)Show InChI InChI=1S/C11H12N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5-6H,3-4,12H2,(H2,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 1D receptor by displacing [125I]GTI from pig caudate |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50421347
(CHEMBL18928)Show InChI InChI=1S/C11H14N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5,8H,3-4,6,12H2,(H2,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-HT1A receptor by displacing [3H]8-OH-DPAT from pig cortex |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50421348
(CHEMBL18710)Show InChI InChI=1S/C13H16N2O2/c1-15(2)6-5-10-8-17-12-4-3-9(13(14)16)7-11(10)12/h3-4,7-8H,5-6H2,1-2H3,(H2,14,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 1D receptor by displacing [125I]GTI from pig caudate |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM21392
(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article
| n/a | n/a | 589 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 2C receptor by displacing [3H]mesulergine from pig cortex |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50421346
(CHEMBL19114)Show InChI InChI=1S/C11H12N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5-6H,3-4,12H2,(H2,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 661 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 2C receptor by displacing [3H]mesulergine from pig cortex |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50421347
(CHEMBL18928)Show InChI InChI=1S/C11H14N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5,8H,3-4,6,12H2,(H2,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 776 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 1D receptor by displacing [125I]GTI from pig caudate |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM50421346
(CHEMBL19114)Show InChI InChI=1S/C11H12N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5-6H,3-4,12H2,(H2,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-HT2A receptor by displacing [3H]-DOB from rat cortex homogenates |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM50421348
(CHEMBL18710)Show InChI InChI=1S/C13H16N2O2/c1-15(2)6-5-10-8-17-12-4-3-9(13(14)16)7-11(10)12/h3-4,7-8H,5-6H2,1-2H3,(H2,14,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 3.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-HT2A receptor by displacing [3H]-DOB from rat cortex homogenates |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(RAT) | BDBM50421348
(CHEMBL18710)Show InChI InChI=1S/C13H16N2O2/c1-15(2)6-5-10-8-17-12-4-3-9(13(14)16)7-11(10)12/h3-4,7-8H,5-6H2,1-2H3,(H2,14,16) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 3 receptor by displacing [3H]-Q-ICS 205-930 from rat cortex homogenates |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50421348
(CHEMBL18710)Show InChI InChI=1S/C13H16N2O2/c1-15(2)6-5-10-8-17-12-4-3-9(13(14)16)7-11(10)12/h3-4,7-8H,5-6H2,1-2H3,(H2,14,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 4.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 2C receptor by displacing [3H]mesulergine from pig cortex |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(RAT) | BDBM50421347
(CHEMBL18928)Show InChI InChI=1S/C11H14N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5,8H,3-4,6,12H2,(H2,13,14) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 4.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 3 receptor by displacing [3H]-Q-ICS 205-930 from rat cortex homogenates |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(RAT) | BDBM50421346
(CHEMBL19114)Show InChI InChI=1S/C11H12N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5-6H,3-4,12H2,(H2,13,14) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 7.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 3 receptor by displacing [3H]-Q-ICS 205-930 from rat cortex homogenates |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50421347
(CHEMBL18928)Show InChI InChI=1S/C11H14N2O2/c12-4-3-8-6-15-10-2-1-7(11(13)14)5-9(8)10/h1-2,5,8H,3-4,6,12H2,(H2,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 8.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-hydroxytryptamine 2C receptor by displacing [3H]mesulergine from pig cortex |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM21392
(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article
| n/a | n/a | 2.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In Vitro Binding affinity againist 5-HT2A receptor by displacing [3H]-DOB from rat cortex homogenates |
Bioorg Med Chem Lett 4: 1207-1212 (1994)
Article DOI: 10.1016/S0960-894X(01)80331-0 BindingDB Entry DOI: 10.7270/Q2TH8P0J |
More data for this Ligand-Target Pair | |