Found 298 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92089
(erk000517)Show SMILES Cc1cnc(Nc2ccccn2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C23H22N6O2/c1-15-12-26-23(28-20-9-5-6-10-24-20)29-21(15)17-11-18(25-13-17)22(31)27-19(14-30)16-7-3-2-4-8-16/h2-13,19,25,30H,14H2,1H3,(H,27,31)(H,24,26,28,29)/t19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| D3R
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92083
(erk000510)Show SMILES C[C@H]1C[C@H]1Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C22H25N5O2/c1-13-8-17(13)26-22-24-10-14(2)20(27-22)16-9-18(23-11-16)21(29)25-19(12-28)15-6-4-3-5-7-15/h3-7,9-11,13,17,19,23,28H,8,12H2,1-2H3,(H,25,29)(H,24,26,27)/t13-,17+,19+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM35654
(erk000526 | pyrimidylpyrrole, 11b)Show SMILES Cc1cccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)c1C |r| Show InChI InChI=1S/C26H26ClN5O2/c1-15-6-4-9-21(17(15)3)31-26-29-12-16(2)24(32-26)19-11-22(28-13-19)25(34)30-23(14-33)18-7-5-8-20(27)10-18/h4-13,23,28,33H,14H2,1-3H3,(H,30,34)(H,29,31,32)/t23-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92109
(erk000541)Show SMILES Cc1cnc(Nc2cccc(CO)c2C)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C26H27N5O3/c1-16-12-28-26(30-21-10-6-9-19(14-32)17(21)2)31-24(16)20-11-22(27-13-20)25(34)29-23(15-33)18-7-4-3-5-8-18/h3-13,23,27,32-33H,14-15H2,1-2H3,(H,29,34)(H,28,30,31)/t23-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92094
(erk000522)Show SMILES CC(C)Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(C)c1 Show InChI InChI=1S/C22H27N5O2/c1-13(2)25-22-24-10-15(4)20(27-22)17-9-18(23-11-17)21(29)26-19(12-28)16-7-5-6-14(3)8-16/h5-11,13,19,23,28H,12H2,1-4H3,(H,26,29)(H,24,25,27)/t19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92039
(erk000445)Show SMILES Cc1cnc(N[C@H](CO)c2ccccc2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C26H27N5O3/c1-17-13-28-26(30-23(16-33)19-10-6-3-7-11-19)31-24(17)20-12-21(27-14-20)25(34)29-22(15-32)18-8-4-2-5-9-18/h2-14,22-23,27,32-33H,15-16H2,1H3,(H,29,34)(H,28,30,31)/t22-,23-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92156
(erk000607)Show SMILES CC(C)[C@@H](C)Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C23H28ClN5O2/c1-13(2)15(4)27-23-26-10-14(3)21(29-23)17-9-19(25-11-17)22(31)28-20(12-30)16-6-5-7-18(24)8-16/h5-11,13,15,20,25,30H,12H2,1-4H3,(H,28,31)(H,26,27,29)/t15-,20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92045
(erk000460)Show SMILES Cc1cnc(NC2(CO)CC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C22H25N5O3/c1-14-10-24-21(27-22(13-29)7-8-22)26-19(14)16-9-17(23-11-16)20(30)25-18(12-28)15-5-3-2-4-6-15/h2-6,9-11,18,23,28-29H,7-8,12-13H2,1H3,(H,25,30)(H,24,26,27)/t18-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92141
(erk000587)Show SMILES Cc1cnc(NN2CCCCC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C23H28N6O2/c1-16-13-25-23(28-29-10-6-3-7-11-29)27-21(16)18-12-19(24-14-18)22(31)26-20(15-30)17-8-4-2-5-9-17/h2,4-5,8-9,12-14,20,24,30H,3,6-7,10-11,15H2,1H3,(H,26,31)(H,25,27,28)/t20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM35649
(erk000537 | pyrimidylpyrrole, 10b)Show SMILES Cc1cnc(Nc2ccccc2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(F)c1 |r| Show InChI InChI=1S/C24H22FN5O2/c1-15-12-27-24(28-19-8-3-2-4-9-19)30-22(15)17-11-20(26-13-17)23(32)29-21(14-31)16-6-5-7-18(25)10-16/h2-13,21,26,31H,14H2,1H3,(H,29,32)(H,27,28,30)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92188
(erk000644)Show SMILES Cc1cnc(NC2CCCC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C23H26ClN5O2/c1-14-11-26-23(27-18-7-2-3-8-18)29-21(14)16-10-19(25-12-16)22(31)28-20(13-30)15-5-4-6-17(24)9-15/h4-6,9-12,18,20,25,30H,2-3,7-8,13H2,1H3,(H,28,31)(H,26,27,29)/t20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92140
(erk000586)Show SMILES Cc1ccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(C)c2)cc1 Show InChI InChI=1S/C26H27N5O2/c1-16-7-9-21(10-8-16)29-26-28-13-18(3)24(31-26)20-12-22(27-14-20)25(33)30-23(15-32)19-6-4-5-17(2)11-19/h4-14,23,27,32H,15H2,1-3H3,(H,30,33)(H,28,29,31)/t23-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92080
(erk000507)Show SMILES CC[C@@H](CO)Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C22H26ClN5O3/c1-3-17(11-29)26-22-25-9-13(2)20(28-22)15-8-18(24-10-15)21(31)27-19(12-30)14-5-4-6-16(23)7-14/h4-10,17,19,24,29-30H,3,11-12H2,1-2H3,(H,27,31)(H,25,26,28)/t17-,19+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
Similars
| PDB
D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92095
(erk000523)Show SMILES CC(C)CNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(C)c1 Show InChI InChI=1S/C23H29N5O2/c1-14(2)10-25-23-26-11-16(4)21(28-23)18-9-19(24-12-18)22(30)27-20(13-29)17-7-5-6-15(3)8-17/h5-9,11-12,14,20,24,29H,10,13H2,1-4H3,(H,27,30)(H,25,26,28)/t20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92165
(erk000616)Show SMILES COc1cccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)c1OC Show InChI InChI=1S/C26H27N5O4/c1-16-13-28-26(30-19-10-7-11-22(34-2)24(19)35-3)31-23(16)18-12-20(27-14-18)25(33)29-21(15-32)17-8-5-4-6-9-17/h4-14,21,27,32H,15H2,1-3H3,(H,29,33)(H,28,30,31)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92199
(erk000658)Show SMILES Cc1cnc(Nc2ccc(F)cc2F)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C24H21F2N5O2/c1-14-11-28-24(30-19-8-7-17(25)10-18(19)26)31-22(14)16-9-20(27-12-16)23(33)29-21(13-32)15-5-3-2-4-6-15/h2-12,21,27,32H,13H2,1H3,(H,29,33)(H,28,30,31)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92036
(erk000441)Show SMILES Cc1ccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)cc1C Show InChI InChI=1S/C26H27N5O2/c1-16-9-10-21(11-17(16)2)29-26-28-13-18(3)24(31-26)20-12-22(27-14-20)25(33)30-23(15-32)19-7-5-4-6-8-19/h4-14,23,27,32H,15H2,1-3H3,(H,30,33)(H,28,29,31)/t23-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92088
(erk000516)Show SMILES Cc1cnc(NC2CCCC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C23H27N5O2/c1-15-12-25-23(26-18-9-5-6-10-18)28-21(15)17-11-19(24-13-17)22(30)27-20(14-29)16-7-3-2-4-8-16/h2-4,7-8,11-13,18,20,24,29H,5-6,9-10,14H2,1H3,(H,27,30)(H,25,26,28)/t20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92122
(erk000558)Show SMILES Cc1cnc(NN2CCOCC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C22H25ClN6O3/c1-14-11-25-22(28-29-5-7-32-8-6-29)27-20(14)16-10-18(24-12-16)21(31)26-19(13-30)15-3-2-4-17(23)9-15/h2-4,9-12,19,24,30H,5-8,13H2,1H3,(H,26,31)(H,25,27,28)/t19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92240
(erk000709)Show SMILES CC[C@@H](CO)Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N(C)[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C23H28ClN5O3/c1-4-18(12-30)27-23-26-10-14(2)21(28-23)16-9-19(25-11-16)22(32)29(3)20(13-31)15-6-5-7-17(24)8-15/h5-11,18,20,25,30-31H,4,12-13H2,1-3H3,(H,26,27,28)/t18-,20+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92067
(erk000492)Show SMILES Cc1cnc(NC2CC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H22F3N5O2/c1-12-9-27-21(28-16-5-6-16)30-19(12)14-8-17(26-10-14)20(32)29-18(11-31)13-3-2-4-15(7-13)22(23,24)25/h2-4,7-10,16,18,26,31H,5-6,11H2,1H3,(H,29,32)(H,27,28,30)/t18-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92033
(erk000438)Show SMILES Cc1cnc(Nc2cccc(c2)C(F)(F)F)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C25H22F3N5O2/c1-15-12-30-24(31-19-9-5-8-18(11-19)25(26,27)28)33-22(15)17-10-20(29-13-17)23(35)32-21(14-34)16-6-3-2-4-7-16/h2-13,21,29,34H,14H2,1H3,(H,32,35)(H,30,31,33)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92106
(erk000538)Show SMILES Cc1cnc(Nc2cccc(F)c2C)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C25H24FN5O2/c1-15-12-28-25(30-20-10-6-9-19(26)16(20)2)31-23(15)18-11-21(27-13-18)24(33)29-22(14-32)17-7-4-3-5-8-17/h3-13,22,27,32H,14H2,1-2H3,(H,29,33)(H,28,30,31)/t22-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92166
(erk000619)Show SMILES Cc1cccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)n1 Show InChI InChI=1S/C24H23ClN6O2/c1-14-11-27-24(30-21-8-3-5-15(2)28-21)31-22(14)17-10-19(26-12-17)23(33)29-20(13-32)16-6-4-7-18(25)9-16/h3-12,20,26,32H,13H2,1-2H3,(H,29,33)(H,27,28,30,31)/t20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92031
(erk000435)Show SMILES Cc1ccc(cc1F)[C@@H](CO)NC(=O)c1cc(c[nH]1)-c1nc(Nc2ccccc2)ncc1C Show InChI InChI=1S/C25H24FN5O2/c1-15-8-9-17(10-20(15)26)22(14-32)30-24(33)21-11-18(13-27-21)23-16(2)12-28-25(31-23)29-19-6-4-3-5-7-19/h3-13,22,27,32H,14H2,1-2H3,(H,30,33)(H,28,29,31)/t22-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92103
(erk000534)Show SMILES Cc1cnc(NC2CCCCC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C24H29N5O2/c1-16-13-26-24(27-19-10-6-3-7-11-19)29-22(16)18-12-20(25-14-18)23(31)28-21(15-30)17-8-4-2-5-9-17/h2,4-5,8-9,12-14,19,21,25,30H,3,6-7,10-11,15H2,1H3,(H,28,31)(H,26,27,29)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92041
(erk000447)Show SMILES Cc1cnc(Nc2ccc(OC(F)(F)F)cc2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C25H22F3N5O3/c1-15-12-30-24(31-18-7-9-19(10-8-18)36-25(26,27)28)33-22(15)17-11-20(29-13-17)23(35)32-21(14-34)16-5-3-2-4-6-16/h2-13,21,29,34H,14H2,1H3,(H,32,35)(H,30,31,33)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92210
(erk000671)Show SMILES OC[C@@H](NC(=O)c1cc(c[nH]1)-c1ncnc(Nc2ccccc2)n1)c1cccc(Cl)c1 Show InChI InChI=1S/C22H19ClN6O2/c23-16-6-4-5-14(9-16)19(12-30)28-21(31)18-10-15(11-24-18)20-25-13-26-22(29-20)27-17-7-2-1-3-8-17/h1-11,13,19,24,30H,12H2,(H,28,31)(H,25,26,27,29)/t19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| D3R
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM35644
(erk000524 | pyrimidylpyrrole, 9c)Show SMILES CCc1ccccc1Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 |r| Show InChI InChI=1S/C26H27N5O2/c1-3-18-9-7-8-12-21(18)30-26-28-14-17(2)24(31-26)20-13-22(27-15-20)25(33)29-23(16-32)19-10-5-4-6-11-19/h4-15,23,27,32H,3,16H2,1-2H3,(H,29,33)(H,28,30,31)/t23-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM91974
(erk000041)Show SMILES CCNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C20H23N5O2/c1-3-21-20-23-10-13(2)18(25-20)15-9-16(22-11-15)19(27)24-17(12-26)14-7-5-4-6-8-14/h4-11,17,22,26H,3,12H2,1-2H3,(H,24,27)(H,21,23,25)/t17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92120
(erk000556)Show SMILES Cc1cnc(Nc2cccc3CCCc23)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C27H27N5O2/c1-17-14-29-27(31-22-12-6-10-18-9-5-11-21(18)22)32-25(17)20-13-23(28-15-20)26(34)30-24(16-33)19-7-3-2-4-8-19/h2-4,6-8,10,12-15,24,28,33H,5,9,11,16H2,1H3,(H,30,34)(H,29,31,32)/t24-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92127
(erk000563)Show SMILES Cc1ccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)cc1Br Show InChI InChI=1S/C25H24BrN5O2/c1-15-8-9-19(11-20(15)26)29-25-28-12-16(2)23(31-25)18-10-21(27-13-18)24(33)30-22(14-32)17-6-4-3-5-7-17/h3-13,22,27,32H,14H2,1-2H3,(H,30,33)(H,28,29,31)/t22-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92130
(erk000566)Show SMILES Cc1cc(C)cc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)c1 Show InChI InChI=1S/C26H27N5O2/c1-16-9-17(2)11-21(10-16)29-26-28-13-18(3)24(31-26)20-12-22(27-14-20)25(33)30-23(15-32)19-7-5-4-6-8-19/h4-14,23,27,32H,15H2,1-3H3,(H,30,33)(H,28,29,31)/t23-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92037
(erk000442)Show SMILES Cc1cnc(Nc2ccc(OCc3ccccc3)cc2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C31H29N5O3/c1-21-17-33-31(34-25-12-14-26(15-13-25)39-20-22-8-4-2-5-9-22)36-29(21)24-16-27(32-18-24)30(38)35-28(19-37)23-10-6-3-7-11-23/h2-18,28,32,37H,19-20H2,1H3,(H,35,38)(H,33,34,36)/t28-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM35665
(erk000617 | pyrimidylpyrrole, 11m)Show SMILES COc1cccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)c1OC |r| Show InChI InChI=1S/C26H26ClN5O4/c1-15-12-29-26(31-19-8-5-9-22(35-2)24(19)36-3)32-23(15)17-11-20(28-13-17)25(34)30-21(14-33)16-6-4-7-18(27)10-16/h4-13,21,28,33H,14H2,1-3H3,(H,30,34)(H,29,31,32)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92229
(erk000697)Show SMILES CC[C@@H](CO)Nc1ncc(F)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C21H23ClFN5O3/c1-2-15(10-29)26-21-25-9-16(23)19(28-21)13-7-17(24-8-13)20(31)27-18(11-30)12-4-3-5-14(22)6-12/h3-9,15,18,24,29-30H,2,10-11H2,1H3,(H,27,31)(H,25,26,28)/t15-,18+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92236
(erk000704)Show SMILES Cc1cnc(N[C@H]2CCOC2)nc1-c1cc(C(=O)N[C@H](CO)c2ccccc2)n(C)c1 Show InChI InChI=1S/C23H27N5O3/c1-15-11-24-23(25-18-8-9-31-14-18)27-21(15)17-10-20(28(2)12-17)22(30)26-19(13-29)16-6-4-3-5-7-16/h3-7,10-12,18-19,29H,8-9,13-14H2,1-2H3,(H,26,30)(H,24,25,27)/t18-,19+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92148
(erk000599)Show SMILES CCONc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(C)c1 Show InChI InChI=1S/C21H25N5O3/c1-4-29-26-21-23-10-14(3)19(25-21)16-9-17(22-11-16)20(28)24-18(12-27)15-7-5-6-13(2)8-15/h5-11,18,22,27H,4,12H2,1-3H3,(H,24,28)(H,23,25,26)/t18-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92151
(erk000602)Show SMILES Cc1cccc(c1)[C@@H](CO)NC(=O)c1cc(c[nH]1)-c1nc(NC2CCOCC2)ncc1C Show InChI InChI=1S/C24H29N5O3/c1-15-4-3-5-17(10-15)21(14-30)28-23(31)20-11-18(13-25-20)22-16(2)12-26-24(29-22)27-19-6-8-32-9-7-19/h3-5,10-13,19,21,25,30H,6-9,14H2,1-2H3,(H,28,31)(H,26,27,29)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92129
(erk000565)Show SMILES Cc1cnc(Nc2cccc(c2)[N+]([O-])=O)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C24H22N6O4/c1-15-12-26-24(27-18-8-5-9-19(11-18)30(33)34)29-22(15)17-10-20(25-13-17)23(32)28-21(14-31)16-6-3-2-4-7-16/h2-13,21,25,31H,14H2,1H3,(H,28,32)(H,26,27,29)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92042
(erk000448)Show SMILES CC(C)CNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C22H27N5O2/c1-14(2)10-24-22-25-11-15(3)20(27-22)17-9-18(23-12-17)21(29)26-19(13-28)16-7-5-4-6-8-16/h4-9,11-12,14,19,23,28H,10,13H2,1-3H3,(H,26,29)(H,24,25,27)/t19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92123
(erk000559)Show SMILES Cc1cnc(Nc2cc(Cl)cc(Cl)c2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C24H21Cl2N5O2/c1-14-11-28-24(29-19-9-17(25)8-18(26)10-19)31-22(14)16-7-20(27-12-16)23(33)30-21(13-32)15-5-3-2-4-6-15/h2-12,21,27,32H,13H2,1H3,(H,30,33)(H,28,29,31)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92195
(erk000653)Show SMILES Cc1ccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)c(C)c1 Show InChI InChI=1S/C26H27N5O2/c1-16-9-10-21(17(2)11-16)30-26-28-13-18(3)24(31-26)20-12-22(27-14-20)25(33)29-23(15-32)19-7-5-4-6-8-19/h4-14,23,27,32H,15H2,1-3H3,(H,29,33)(H,28,30,31)/t23-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92208
(erk000668)Show SMILES Cc1cc(N)ccc1Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C25H25ClN6O2/c1-14-8-19(27)6-7-20(14)31-25-29-11-15(2)23(32-25)17-10-21(28-12-17)24(34)30-22(13-33)16-4-3-5-18(26)9-16/h3-12,22,28,33H,13,27H2,1-2H3,(H,30,34)(H,29,31,32)/t22-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92097
(erk000527)Show SMILES Cc1cnc(Nc2cccc(O)c2C)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 Show InChI InChI=1S/C25H25N5O3/c1-15-12-27-25(29-19-9-6-10-22(32)16(19)2)30-23(15)18-11-20(26-13-18)24(33)28-21(14-31)17-7-4-3-5-8-17/h3-13,21,26,31-32H,14H2,1-2H3,(H,28,33)(H,27,29,30)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92202
(erk000661)Show SMILES Cc1cnc(NNS(C)(=O)=O)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C19H21ClN6O4S/c1-11-8-22-19(25-26-31(2,29)30)24-17(11)13-7-15(21-9-13)18(28)23-16(10-27)12-4-3-5-14(20)6-12/h3-9,16,21,26-27H,10H2,1-2H3,(H,23,28)(H,22,24,25)/t16-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92096
(erk000525)Show SMILES CC(C)CNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1 Show InChI InChI=1S/C22H26ClN5O2/c1-13(2)9-25-22-26-10-14(3)20(28-22)16-8-18(24-11-16)21(30)27-19(12-29)15-5-4-6-17(23)7-15/h4-8,10-11,13,19,24,29H,9,12H2,1-3H3,(H,27,30)(H,25,26,28)/t19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM35647
(erk000636 | pyrimidylpyrrole, 9f)Show SMILES Cc1cnc(Nc2ccccc2O)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1 |r| Show InChI InChI=1S/C24H23N5O3/c1-15-12-26-24(28-18-9-5-6-10-21(18)31)29-22(15)17-11-19(25-13-17)23(32)27-20(14-30)16-7-3-2-4-8-16/h2-13,20,25,30-31H,14H2,1H3,(H,27,32)(H,26,28,29)/t20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92090
(erk000518)Show SMILES Cc1ccnc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)c1 Show InChI InChI=1S/C24H24N6O2/c1-15-8-9-25-21(10-15)29-24-27-12-16(2)22(30-24)18-11-19(26-13-18)23(32)28-20(14-31)17-6-4-3-5-7-17/h3-13,20,26,31H,14H2,1-2H3,(H,28,32)(H,25,27,29,30)/t20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM92194
(erk000652)Show SMILES Cc1csc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)n1 Show InChI InChI=1S/C22H21ClN6O2S/c1-12-8-25-21(29-22-26-13(2)11-32-22)28-19(12)15-7-17(24-9-15)20(31)27-18(10-30)14-4-3-5-16(23)6-14/h3-9,11,18,24,30H,10H2,1-2H3,(H,27,31)(H,25,26,28,29)/t18-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| D3R
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description
Photometric_Method2 |
D3R 222: (2015)
BindingDB Entry DOI: 10.7270/Q2S46QSD |
More data for this
Ligand-Target Pair | |
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