Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50083940 (4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | D3R | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50174491 ((Z)-2-Hydroxy-4-oxo-4-m-tolyl-but-2-enoic acid | C...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | D3R | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50152579 (4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid | CHEMB...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | D3R | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50152554 (4-(2-Chloro-phenyl)-2,4-dioxo-butyric acid | CHEMB...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | D3R | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225389 (Sacchettini_4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid PDB UniChem | PDB D3R | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50083953 ((Z)-4-(3-Bromo-phenyl)-2-hydroxy-4-oxo-but-2-enoic...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB D3R | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50152575 (2,4-Dioxo-4-o-tolyl-butyric acid | CHEMBL1829214 |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PDB D3R | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50115579 ((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB D3R | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225391 (Sacchettini_10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | D3R | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225392 (Sacchettini_11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid PDB UniChem | PDB D3R | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225390 (Sacchettini_9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | D3R | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50137853 (2,4-Dioxo-4-p-tolyl-butyric acid | 2,4-dioxo-4-p-t...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | D3R | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225397 (Sacchettini_24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | D3R | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225393 (Sacchettini_20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | D3R | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225398 (Sacchettini_25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | D3R | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225394 (Sacchettini_21) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | D3R | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225399 (Sacchettini_26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | D3R | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225396 (Sacchettini_23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | D3R | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM225395 (Sacchettini_22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | D3R | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description DNTB-Coupled_Enzyme_Assay | D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G | |||||||||||
More data for this Ligand-Target Pair |