Found 30 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dihydrofolate reductase
(Escherichia coli) | BDBM18069
(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)Show InChI InChI=1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50138701
(6-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,...)Show InChI InChI=1S/C15H20N4O3/c1-8-10(14(16)19-15(17)18-8)5-9-6-11(20-2)13(22-4)12(7-9)21-3/h6-7H,5H2,1-4H3,(H4,16,17,18,19) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Bifunctional dihydrofolate reductase-thymidylate synthase
(Plasmodium berghei (strain Anka)) | BDBM18069
(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)Show InChI InChI=1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for its inhibition against dihydrofolate reductase enzyme of Plasmodium berghei |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50404463
(CHEMBL339058)Show InChI InChI=1S/C14H18N4O3/c1-7-9(13(15)18-14(16)17-7)4-8-5-10(20-2)12(19)11(6-8)21-3/h5-6,19H,4H2,1-3H3,(H4,15,16,17,18) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Bifunctional dihydrofolate reductase-thymidylate synthase
(Plasmodium berghei (strain Anka)) | BDBM50138701
(6-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,...)Show InChI InChI=1S/C15H20N4O3/c1-8-10(14(16)19-15(17)18-8)5-9-6-11(20-2)13(22-4)12(7-9)21-3/h6-7H,5H2,1-4H3,(H4,16,17,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for its inhibition against dihydrofolate reductase enzyme of Plasmodium berghei |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Bifunctional dihydrofolate reductase-thymidylate synthase
(Plasmodium berghei (strain Anka)) | BDBM50404463
(CHEMBL339058)Show InChI InChI=1S/C14H18N4O3/c1-7-9(13(15)18-14(16)17-7)4-8-5-10(20-2)12(19)11(6-8)21-3/h5-6,19H,4H2,1-3H3,(H4,15,16,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for its inhibition against dihydrofolate reductase enzyme of Plasmodium berghei |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50421660
(CHEMBL149353)Show InChI InChI=1S/C16H22N4O3/c1-4-5-11-10(15(17)20-16(18)19-11)6-9-7-12(22-2)14(21)13(8-9)23-3/h7-8,21H,4-6H2,1-3H3,(H4,17,18,19,20) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Bifunctional dihydrofolate reductase-thymidylate synthase
(Plasmodium berghei (strain Anka)) | BDBM50421660
(CHEMBL149353)Show InChI InChI=1S/C16H22N4O3/c1-4-5-11-10(15(17)20-16(18)19-11)6-9-7-12(22-2)14(21)13(8-9)23-3/h7-8,21H,4-6H2,1-3H3,(H4,17,18,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for its inhibition against dihydrofolate reductase enzyme of Plasmodium berghei |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50404479
(CHEMBL150543)Show InChI InChI=1S/C17H24N4O3/c1-5-6-12-11(16(18)21-17(19)20-12)7-10-8-13(22-2)15(24-4)14(9-10)23-3/h8-9H,5-7H2,1-4H3,(H4,18,19,20,21) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50404474
(CHEMBL357960)Show InChI InChI=1S/C17H24N4O3/c1-9(2)14-11(16(18)21-17(19)20-14)6-10-7-12(22-3)15(24-5)13(8-10)23-4/h7-9H,6H2,1-5H3,(H4,18,19,20,21) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50421665
(CHEMBL150248)Show InChI InChI=1S/C19H20N4O3/c1-25-14-9-11(10-15(26-2)17(14)24)8-13-16(12-6-4-3-5-7-12)22-19(21)23-18(13)20/h3-7,9-10,24H,8H2,1-2H3,(H4,20,21,22,23) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50421662
(CHEMBL358879)Show InChI InChI=1S/C20H22N4O3/c1-25-15-10-12(11-16(26-2)18(15)27-3)9-14-17(13-7-5-4-6-8-13)23-20(22)24-19(14)21/h4-8,10-11H,9H2,1-3H3,(H4,21,22,23,24) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50404475
(CHEMBL149408)Show InChI InChI=1S/C14H19N5O3/c1-20-9-5-7(6-10(21-2)11(9)22-3)4-8-12(15)18-14(17)19-13(8)16/h5-6H,4H2,1-3H3,(H6,15,16,17,18,19) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Bifunctional dihydrofolate reductase-thymidylate synthase
(Plasmodium berghei (strain Anka)) | BDBM50404477
(CHEMBL150538)Show InChI InChI=1S/C15H20N4O3S/c1-20-10-6-8(7-11(21-2)12(10)22-3)5-9-13(16)18-15(17)19-14(9)23-4/h6-7H,5H2,1-4H3,(H4,16,17,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested for the inhibition of Plasmodium berghei dihydrofolate reductase enzyme |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50421664
(CHEMBL150683)Show InChI InChI=1S/C17H24N4OS/c1-5-11-7-10(8-12(6-2)14(11)22-3)9-13-15(18)20-17(19)21-16(13)23-4/h7-8H,5-6,9H2,1-4H3,(H4,18,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50421664
(CHEMBL150683)Show InChI InChI=1S/C17H24N4OS/c1-5-11-7-10(8-12(6-2)14(11)22-3)9-13-15(18)20-17(19)21-16(13)23-4/h7-8H,5-6,9H2,1-4H3,(H4,18,19,20,21) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50421663
(CHEMBL150863)Show InChI InChI=1S/C20H22N4O4/c1-25-15-10-12(11-16(26-2)17(15)27-3)9-14-18(21)23-20(22)24-19(14)28-13-7-5-4-6-8-13/h4-8,10-11H,9H2,1-3H3,(H4,21,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50421663
(CHEMBL150863)Show InChI InChI=1S/C20H22N4O4/c1-25-15-10-12(11-16(26-2)17(15)27-3)9-14-18(21)23-20(22)24-19(14)28-13-7-5-4-6-8-13/h4-8,10-11H,9H2,1-3H3,(H4,21,22,23,24) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50421665
(CHEMBL150248)Show InChI InChI=1S/C19H20N4O3/c1-25-14-9-11(10-15(26-2)17(14)24)8-13-16(12-6-4-3-5-7-12)22-19(21)23-18(13)20/h3-7,9-10,24H,8H2,1-2H3,(H4,20,21,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50404478
(CHEMBL439995)Show SMILES COc1c(cc(Cc2c(N)nc(N)nc2N)cc1C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C20H31N5O/c1-19(2,3)13-9-11(10-14(15(13)26-7)20(4,5)6)8-12-16(21)24-18(23)25-17(12)22/h9-10H,8H2,1-7H3,(H6,21,22,23,24,25) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50404473
(CHEMBL150700)Show InChI InChI=1S/C15H20N4O4/c1-20-10-6-8(7-11(21-2)12(10)22-3)5-9-13(16)18-15(17)19-14(9)23-4/h6-7H,5H2,1-4H3,(H4,16,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM18069
(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)Show InChI InChI=1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50421662
(CHEMBL358879)Show InChI InChI=1S/C20H22N4O3/c1-25-15-10-12(11-16(26-2)18(15)27-3)9-14-17(13-7-5-4-6-8-13)23-20(22)24-19(14)21/h4-8,10-11H,9H2,1-3H3,(H4,21,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50138701
(6-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,...)Show InChI InChI=1S/C15H20N4O3/c1-8-10(14(16)19-15(17)18-8)5-9-6-11(20-2)13(22-4)12(7-9)21-3/h6-7H,5H2,1-4H3,(H4,16,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50404477
(CHEMBL150538)Show InChI InChI=1S/C15H20N4O3S/c1-20-10-6-8(7-11(21-2)12(10)22-3)5-9-13(16)18-15(17)19-14(9)23-4/h6-7H,5H2,1-4H3,(H4,16,17,18,19) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50404477
(CHEMBL150538)Show InChI InChI=1S/C15H20N4O3S/c1-20-10-6-8(7-11(21-2)12(10)22-3)5-9-13(16)18-15(17)19-14(9)23-4/h6-7H,5H2,1-4H3,(H4,16,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50404473
(CHEMBL150700)Show InChI InChI=1S/C15H20N4O4/c1-20-10-6-8(7-11(21-2)12(10)22-3)5-9-13(16)18-15(17)19-14(9)23-4/h6-7H,5H2,1-4H3,(H4,16,17,18,19) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >4.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50404475
(CHEMBL149408)Show InChI InChI=1S/C14H19N5O3/c1-20-9-5-7(6-10(21-2)11(9)22-3)4-8-12(15)18-14(17)19-13(8)16/h5-6H,4H2,1-3H3,(H6,15,16,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >9.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Rattus norvegicus (rat)) | BDBM50404479
(CHEMBL150543)Show InChI InChI=1S/C17H24N4O3/c1-5-6-12-11(16(18)21-17(19)20-12)7-10-8-13(22-2)15(24-4)14(9-10)23-3/h8-9H,5-7H2,1-4H3,(H4,18,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of rat liver |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |
Dihydrofolate reductase
(Escherichia coli) | BDBM50421661
(CHEMBL150017)Show InChI InChI=1S/C16H23N5O3/c1-21(2)15-10(14(17)19-16(18)20-15)6-9-7-11(22-3)13(24-5)12(8-9)23-4/h7-8H,6H2,1-5H3,(H4,17,18,19,20) | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 4.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition against dihydrofolate reductase enzyme of Escherichia coli |
J Med Chem 23: 535-41 (1980)
BindingDB Entry DOI: 10.7270/Q2TX3GJG |
More data for this Ligand-Target Pair | |