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PubMed code 7707322

Compile data set for download or QSAR
Found 52 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50004327
PNG
((1-Phenethyl-piperidin-4-yl)-phenyl-methanol | CHE...)
Show SMILES OC(C1CCN(CCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C20H25NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19-20,22H,11-16H2
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 2.5n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034202
PNG
((4-Fluoro-phenyl)-(1-phenethyl-piperidin-4-yl)-met...)
Show SMILES OC(C1CCN(CCc2ccccc2)CC1)c1ccc(F)cc1
Show InChI InChI=1S/C20H24FNO/c21-19-8-6-17(7-9-19)20(23)18-11-14-22(15-12-18)13-10-16-4-2-1-3-5-16/h1-9,18,20,23H,10-15H2
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 3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50004337
PNG
((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C22H26FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20H,4-5,8,13-17H2
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 5.30n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034198
PNG
(4-Benzhydrylidene-1-phenethyl-piperidine | CHEMBL1...)
Show SMILES [#6](-[#6]-c1ccccc1)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C26H27N/c1-4-10-22(11-5-1)16-19-27-20-17-25(18-21-27)26(23-12-6-2-7-13-23)24-14-8-3-9-15-24/h1-15H,16-21H2
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 6.90n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50454090
PNG
(CHEMBL19491)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C20H22FNO/c21-19-8-6-17(7-9-19)20(23)18-11-14-22(15-12-18)13-10-16-4-2-1-3-5-16/h1-9,18H,10-15H2
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 8.5n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034203
PNG
((1-Phenethyl-piperidin-4-yl)-phenyl-methanone | CH...)
Show SMILES O=C(C1CCN(CCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C20H23NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19H,11-16H2
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 9.60n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034194
PNG
(CHEMBL19262 | Phenyl-[1-(4-phenyl-butyl)-piperidin...)
Show SMILES O=C(C1CCN(CCCCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C22H27NO/c24-22(20-12-5-2-6-13-20)21-14-17-23(18-15-21)16-8-7-11-19-9-3-1-4-10-19/h1-6,9-10,12-13,21H,7-8,11,14-18H2
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 10n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034197
PNG
(3-[2-(4-Benzhydryl-piperidin-1-yl)-ethyl]-1H-quina...)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1CCN1CCC(CC1)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H29N3O2/c32-27-24-13-7-8-14-25(24)29-28(33)31(27)20-19-30-17-15-23(16-18-30)26(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-14,23,26H,15-20H2,(H,29,33)
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 18n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034209
PNG
(4-(4-Fluoro-benzyl)-1-phenethyl-piperidine | CHEMB...)
Show SMILES Fc1ccc(CC2CCN(CCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H24FN/c21-20-8-6-18(7-9-20)16-19-11-14-22(15-12-19)13-10-17-4-2-1-3-5-17/h1-9,19H,10-16H2
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 18n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034213
PNG
(4-((E)-1,2-Diphenyl-vinyl)-1-phenethyl-piperidine ...)
Show SMILES C(Cc1ccccc1)N1CCC(CC1)C(=C/c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C27H29N/c1-4-10-23(11-5-1)16-19-28-20-17-26(18-21-28)27(25-14-8-3-9-15-25)22-24-12-6-2-7-13-24/h1-15,22,26H,16-21H2/b27-22-
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 19n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034199
PNG
(4-Benzhydrylidene-1-(4-phenyl-butyl)-piperidine | ...)
Show SMILES [#6](-[#6]-[#6]-c1ccccc1)-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C28H31N/c1-4-12-24(13-5-1)14-10-11-21-29-22-19-27(20-23-29)28(25-15-6-2-7-16-25)26-17-8-3-9-18-26/h1-9,12-13,15-18H,10-11,14,19-23H2
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 20n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50007676
PNG
(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H25N/c1-3-7-18(8-4-1)11-14-21-15-12-20(13-16-21)17-19-9-5-2-6-10-19/h1-10,20H,11-17H2
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 22n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034198
PNG
(4-Benzhydrylidene-1-phenethyl-piperidine | CHEMBL1...)
Show SMILES [#6](-[#6]-c1ccccc1)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C26H27N/c1-4-10-22(11-5-1)16-19-27-20-17-25(18-21-27)26(23-12-6-2-7-13-23)24-14-8-3-9-15-24/h1-15H,16-21H2
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 29n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034195
PNG
(4-(4-Fluoro-benzyl)-1-(4-phenyl-butyl)-piperidine ...)
Show SMILES Fc1ccc(CC2CCN(CCCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H28FN/c23-22-11-9-20(10-12-22)18-21-13-16-24(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21H,4-5,8,13-18H2
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 40n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034197
PNG
(3-[2-(4-Benzhydryl-piperidin-1-yl)-ethyl]-1H-quina...)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1CCN1CCC(CC1)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H29N3O2/c32-27-24-13-7-8-14-25(24)29-28(33)31(27)20-19-30-17-15-23(16-18-30)26(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-14,23,26H,15-20H2,(H,29,33)
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 52n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034201
PNG
(4-((E)-1,4-Diphenyl-but-1-enyl)-1-(4-phenyl-butyl)...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)C(=C/CCc1ccccc1)\c1ccccc1
Show InChI InChI=1S/C31H37N/c1-4-13-27(14-5-1)17-10-11-24-32-25-22-30(23-26-32)31(29-19-8-3-9-20-29)21-12-18-28-15-6-2-7-16-28/h1-9,13-16,19-21,30H,10-12,17-18,22-26H2/b31-21-
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 53n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034211
PNG
(3-[2-(4-Benzhydryl-piperazin-1-yl)-ethyl]-1H-quina...)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1CCN1CCN(CC1)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H28N4O2/c32-26-23-13-7-8-14-24(23)28-27(33)31(26)20-17-29-15-18-30(19-16-29)25(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-14,25H,15-20H2,(H,28,33)
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 62n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034196
PNG
(4-((Z)-1,2-Diphenyl-vinyl)-1-(4-phenyl-butyl)-pipe...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)C(=C\c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C29H33N/c1-4-12-25(13-5-1)14-10-11-21-30-22-19-28(20-23-30)29(27-17-8-3-9-18-27)24-26-15-6-2-7-16-26/h1-9,12-13,15-18,24,28H,10-11,14,19-23H2/b29-24+
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 98n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034193
PNG
(4-((E)-1,3-Diphenyl-propenyl)-1-(4-phenyl-butyl)-p...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)C(=C/Cc1ccccc1)\c1ccccc1
Show InChI InChI=1S/C30H35N/c1-4-12-26(13-5-1)16-10-11-23-31-24-21-29(22-25-31)30(28-17-8-3-9-18-28)20-19-27-14-6-2-7-15-27/h1-9,12-15,17-18,20,29H,10-11,16,19,21-25H2/b30-20-
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 100n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034212
PNG
(4-Benzyl-1-(4-phenyl-butyl)-piperidine | CHEMBL276...)
Show SMILES C(CCc1ccccc1)CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H29N/c1-3-9-20(10-4-1)11-7-8-16-23-17-14-22(15-18-23)19-21-12-5-2-6-13-21/h1-6,9-10,12-13,22H,7-8,11,14-19H2
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 120n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034200
PNG
((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...)
Show SMILES OC(C1CCN(CCCCc2ccccc2)CC1)c1ccc(F)cc1
Show InChI InChI=1S/C22H28FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,22,25H,4-5,8,13-17H2
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 126n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034208
PNG
(4-((Z)-1,2-Diphenyl-vinyl)-1-methyl-piperidine | C...)
Show SMILES CN1CCC(CC1)C(=C\c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C20H23N/c1-21-14-12-19(13-15-21)20(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-11,16,19H,12-15H2,1H3/b20-16+
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 130n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034207
PNG
(1-((E)-1,2-Diphenyl-vinyl)-4-(4-phenyl-butyl)-pipe...)
Show SMILES C(CCc1ccccc1)CN1CCN(CC1)C(=C\c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C28H32N2/c1-4-12-25(13-5-1)14-10-11-19-29-20-22-30(23-21-29)28(27-17-8-3-9-18-27)24-26-15-6-2-7-16-26/h1-9,12-13,15-18,24H,10-11,14,19-23H2/b28-24+
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 140n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50454090
PNG
(CHEMBL19491)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C20H22FNO/c21-19-8-6-17(7-9-19)20(23)18-11-14-22(15-12-18)13-10-16-4-2-1-3-5-16/h1-9,18H,10-15H2
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 145n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50007413
PNG
(CHEMBL19351 | Phenyl-[4-(4-phenyl-butyl)-piperazin...)
Show SMILES O=C(N1CCN(CCCCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c24-21(20-12-5-2-6-13-20)23-17-15-22(16-18-23)14-8-7-11-19-9-3-1-4-10-19/h1-6,9-10,12-13H,7-8,11,14-18H2
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 180n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034199
PNG
(4-Benzhydrylidene-1-(4-phenyl-butyl)-piperidine | ...)
Show SMILES [#6](-[#6]-[#6]-c1ccccc1)-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C28H31N/c1-4-12-24(13-5-1)14-10-11-21-29-22-19-27(20-23-29)28(25-15-6-2-7-16-25)26-17-8-3-9-18-26/h1-9,12-13,15-18H,10-11,14,19-23H2
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 220n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034204
PNG
(1-Benzyl-4-(4-phenyl-butyl)-piperazine | CHEMBL193...)
Show SMILES C(CCc1ccccc1)CN1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H28N2/c1-3-9-20(10-4-1)11-7-8-14-22-15-17-23(18-16-22)19-21-12-5-2-6-13-21/h1-6,9-10,12-13H,7-8,11,14-19H2
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 240n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034210
PNG
(CHEMBL18905 | Phenyl-[1-(4-phenyl-butyl)-piperidin...)
Show SMILES OC(C1CCN(CCCCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C22H29NO/c24-22(20-12-5-2-6-13-20)21-14-17-23(18-15-21)16-8-7-11-19-9-3-1-4-10-19/h1-6,9-10,12-13,21-22,24H,7-8,11,14-18H2
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 265n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034206
PNG
(1-((E)-1,2-Diphenyl-vinyl)-4-methyl-piperazine | C...)
Show SMILES CN1CCN(CC1)C(=C\c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C19H22N2/c1-20-12-14-21(15-13-20)19(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-11,16H,12-15H2,1H3/b19-16+
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 330n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034201
PNG
(4-((E)-1,4-Diphenyl-but-1-enyl)-1-(4-phenyl-butyl)...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)C(=C/CCc1ccccc1)\c1ccccc1
Show InChI InChI=1S/C31H37N/c1-4-13-27(14-5-1)17-10-11-24-32-25-22-30(23-26-32)31(29-19-8-3-9-20-29)21-12-18-28-15-6-2-7-16-28/h1-9,13-16,19-21,30H,10-12,17-18,22-26H2/b31-21-
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 455n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50034205
PNG
((1-Methyl-piperidin-4-yl)-phenyl-methanone | CHEMB...)
Show SMILES CN1CCC(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C13H17NO/c1-14-9-7-12(8-10-14)13(15)11-5-3-2-4-6-11/h2-6,12H,7-10H2,1H3
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 600n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2A receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50004337
PNG
((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C22H26FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20H,4-5,8,13-17H2
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 620n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034211
PNG
(3-[2-(4-Benzhydryl-piperazin-1-yl)-ethyl]-1H-quina...)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1CCN1CCN(CC1)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H28N4O2/c32-26-23-13-7-8-14-24(23)28-27(33)31(26)20-17-29-15-18-30(19-16-29)25(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-14,25H,15-20H2,(H,28,33)
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 635n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034203
PNG
((1-Phenethyl-piperidin-4-yl)-phenyl-methanone | CH...)
Show SMILES O=C(C1CCN(CCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C20H23NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19H,11-16H2
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 800n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50004327
PNG
((1-Phenethyl-piperidin-4-yl)-phenyl-methanol | CHE...)
Show SMILES OC(C1CCN(CCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C20H25NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19-20,22H,11-16H2
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 830n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034208
PNG
(4-((Z)-1,2-Diphenyl-vinyl)-1-methyl-piperidine | C...)
Show SMILES CN1CCC(CC1)C(=C\c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C20H23N/c1-21-14-12-19(13-15-21)20(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-11,16,19H,12-15H2,1H3/b20-16+
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 1.23E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034193
PNG
(4-((E)-1,3-Diphenyl-propenyl)-1-(4-phenyl-butyl)-p...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)C(=C/Cc1ccccc1)\c1ccccc1
Show InChI InChI=1S/C30H35N/c1-4-12-26(13-5-1)16-10-11-23-31-24-21-29(22-25-31)30(28-17-8-3-9-18-28)20-19-27-14-6-2-7-15-27/h1-9,12-15,17-18,20,29H,10-11,16,19,21-25H2/b30-20-
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 1.39E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034202
PNG
((4-Fluoro-phenyl)-(1-phenethyl-piperidin-4-yl)-met...)
Show SMILES OC(C1CCN(CCc2ccccc2)CC1)c1ccc(F)cc1
Show InChI InChI=1S/C20H24FNO/c21-19-8-6-17(7-9-19)20(23)18-11-14-22(15-12-18)13-10-16-4-2-1-3-5-16/h1-9,18,20,23H,10-15H2
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 1.52E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50007676
PNG
(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H25N/c1-3-7-18(8-4-1)11-14-21-15-12-20(13-16-21)17-19-9-5-2-6-10-19/h1-10,20H,11-17H2
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 1.76E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034196
PNG
(4-((Z)-1,2-Diphenyl-vinyl)-1-(4-phenyl-butyl)-pipe...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)C(=C\c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C29H33N/c1-4-12-25(13-5-1)14-10-11-21-30-22-19-28(20-23-30)29(27-17-8-3-9-18-27)24-26-15-6-2-7-16-26/h1-9,12-13,15-18,24,28H,10-11,14,19-23H2/b29-24+
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 1.77E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034209
PNG
(4-(4-Fluoro-benzyl)-1-phenethyl-piperidine | CHEMB...)
Show SMILES Fc1ccc(CC2CCN(CCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H24FN/c21-20-8-6-18(7-9-20)16-19-11-14-22(15-12-19)13-10-17-4-2-1-3-5-17/h1-9,19H,10-16H2
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 2.00E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034194
PNG
(CHEMBL19262 | Phenyl-[1-(4-phenyl-butyl)-piperidin...)
Show SMILES O=C(C1CCN(CCCCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C22H27NO/c24-22(20-12-5-2-6-13-20)21-14-17-23(18-15-21)16-8-7-11-19-9-3-1-4-10-19/h1-6,9-10,12-13,21H,7-8,11,14-18H2
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 2.40E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034207
PNG
(1-((E)-1,2-Diphenyl-vinyl)-4-(4-phenyl-butyl)-pipe...)
Show SMILES C(CCc1ccccc1)CN1CCN(CC1)C(=C\c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C28H32N2/c1-4-12-25(13-5-1)14-10-11-19-29-20-22-30(23-21-29)28(27-17-8-3-9-18-27)24-26-15-6-2-7-16-26/h1-9,12-13,15-18,24H,10-11,14,19-23H2/b28-24+
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 2.60E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034195
PNG
(4-(4-Fluoro-benzyl)-1-(4-phenyl-butyl)-piperidine ...)
Show SMILES Fc1ccc(CC2CCN(CCCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H28FN/c23-22-11-9-20(10-12-22)18-21-13-16-24(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21H,4-5,8,13-18H2
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 2.74E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034206
PNG
(1-((E)-1,2-Diphenyl-vinyl)-4-methyl-piperazine | C...)
Show SMILES CN1CCN(CC1)C(=C\c1ccccc1)\c1ccccc1
Show InChI InChI=1S/C19H22N2/c1-20-12-14-21(15-13-20)19(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-11,16H,12-15H2,1H3/b19-16+
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 2.87E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034212
PNG
(4-Benzyl-1-(4-phenyl-butyl)-piperidine | CHEMBL276...)
Show SMILES C(CCc1ccccc1)CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H29N/c1-3-9-20(10-4-1)11-7-8-16-23-17-14-22(15-18-23)19-21-12-5-2-6-13-21/h1-6,9-10,12-13,22H,7-8,11,14-19H2
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 4.12E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034200
PNG
((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...)
Show SMILES OC(C1CCN(CCCCc2ccccc2)CC1)c1ccc(F)cc1
Show InChI InChI=1S/C22H28FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,22,25H,4-5,8,13-17H2
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 6.60E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50007413
PNG
(CHEMBL19351 | Phenyl-[4-(4-phenyl-butyl)-piperazin...)
Show SMILES O=C(N1CCN(CCCCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c24-21(20-12-5-2-6-13-20)23-17-15-22(16-18-23)14-8-7-11-19-9-3-1-4-10-19/h1-6,9-10,12-13H,7-8,11,14-18H2
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 8.52E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034210
PNG
(CHEMBL18905 | Phenyl-[1-(4-phenyl-butyl)-piperidin...)
Show SMILES OC(C1CCN(CCCCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C22H29NO/c24-22(20-12-5-2-6-13-20)21-14-17-23(18-15-21)16-8-7-11-19-9-3-1-4-10-19/h1-6,9-10,12-13,21-22,24H,7-8,11,14-18H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034204
PNG
(1-Benzyl-4-(4-phenyl-butyl)-piperazine | CHEMBL193...)
Show SMILES C(CCc1ccccc1)CN1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H28N2/c1-3-9-20(10-4-1)11-7-8-14-22-15-17-23(18-16-22)19-21-12-5-2-6-13-21/h1-6,9-10,12-13H,7-8,11,14-19H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50004309
PNG
((4-Methyl-piperazin-1-yl)-phenyl-methanone | CHEMB...)
Show SMILES CN1CCN(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C12H16N2O/c1-13-7-9-14(10-8-13)12(15)11-5-3-2-4-6-11/h2-6H,7-10H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50034205
PNG
((1-Methyl-piperidin-4-yl)-phenyl-methanone | CHEMB...)
Show SMILES CN1CCC(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C13H17NO/c1-14-9-7-12(8-10-14)13(15)11-5-3-2-4-6-11/h2-6,12H,7-10H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor

J Med Chem 38: 1196-202 (1995)


BindingDB Entry DOI: 10.7270/Q2CZ37TG
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%