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PubMed code 7837220

Compile data set for download or QSAR
Found 5 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50002692
PNG
((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Show SMILES Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O |r|
Show InChI InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem

Patents

PubMed
n/an/a 30n/an/an/an/an/an/a



BioChem Therapeutic Inc.

Curated by ChEMBL


Assay Description
Ability to inhibit the HIV-1 reverse transcriptase in cord blood mononuclear cells.


J Med Chem 38: 1-4 (1995)

More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50035784
PNG
(4-Amino-5-fluoro-1-((3R,5R)-5-hydroxymethyl-tetrah...)
Show SMILES Nc1nc(=O)n(cc1F)[C@H]1CS[C@@H](CO)C1
Show InChI InChI=1S/C9H12FN3O2S/c10-7-2-13(9(15)12-8(7)11)5-1-6(3-14)16-4-5/h2,5-6,14H,1,3-4H2,(H2,11,12,15)/t5-,6-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 200n/an/an/an/an/an/a



BioChem Therapeutic Inc.

Curated by ChEMBL


Assay Description
Ability to inhibit the HIV-1 reverse transcriptase in cord blood mononuclear cells.


J Med Chem 38: 1-4 (1995)

More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50035787
PNG
(4-Amino-5-fluoro-1-((2S,5R)-5-hydroxymethyl-tetrah...)
Show SMILES Nc1nc(=O)n(cc1F)[C@@H]1CC[C@H](CO)S1
Show InChI InChI=1S/C9H12FN3O2S/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h3,5,7,14H,1-2,4H2,(H2,11,12,15)/t5-,7+/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 250n/an/an/an/an/an/a



BioChem Therapeutic Inc.

Curated by ChEMBL


Assay Description
Ability to inhibit the HIV-1 reverse transcriptase in cord blood mononuclear cells.


J Med Chem 38: 1-4 (1995)

More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50035785
PNG
(4-Amino-1-((2S,5R)-5-hydroxymethyl-tetrahydro-thio...)
Show SMILES Nc1ccn([C@@H]2CC[C@H](CO)S2)c(=O)n1
Show InChI InChI=1S/C9H13N3O2S/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 287n/an/an/an/an/an/a



BioChem Therapeutic Inc.

Curated by ChEMBL


Assay Description
Ability to inhibit the HIV-1 reverse transcriptase in cord blood mononuclear cells.


J Med Chem 38: 1-4 (1995)

More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50035786
PNG
(4-Amino-1-((3R,5R)-5-hydroxymethyl-tetrahydro-thio...)
Show SMILES Nc1ccn([C@H]2CS[C@@H](CO)C2)c(=O)n1
Show InChI InChI=1S/C9H13N3O2S/c10-8-1-2-12(9(14)11-8)6-3-7(4-13)15-5-6/h1-2,6-7,13H,3-5H2,(H2,10,11,14)/t6-,7-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 355n/an/an/an/an/an/a



BioChem Therapeutic Inc.

Curated by ChEMBL


Assay Description
Ability to inhibit the HIV-1 reverse transcriptase in cord blood mononuclear cells.


J Med Chem 38: 1-4 (1995)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%