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PubMed code 7932553

Compile data set for download or QSAR
Found 42 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035320
PNG
((+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1
Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3
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 1.30n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035303
PNG
((R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1
Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m1/s1
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 1.40n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50037272
PNG
((R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]c(cc3c2C1)C#N
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-19-18(17(14)12-16)11-15(13-20)21-19/h6,8,11,16,21H,3-5,7,9-10,12H2,1-2H3/t16-/m1/s1
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 1.70n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035326
PNG
(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C#N)c3c2C1
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3
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 1.80n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035305
PNG
((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1
Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m0/s1
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 2n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035328
PNG
((R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C#N)c3c2C1
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3/t16-/m1/s1
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 2.70n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035324
PNG
((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C#N)c3c2C1
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3/t16-/m0/s1
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 2.90n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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 7n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
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 8.70n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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 12n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035306
PNG
((1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1
Show InChI InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3
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 12.6n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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 14n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50020222
PNG
((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)
Show SMILES CCCN(CCC)C1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3
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 54n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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 100n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035320
PNG
((+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1
Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3
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 120n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50037274
PNG
(CHEMBL308143 | Dipropyl-(6,7,8,9-tetrahydro-1H-ben...)
Show SMILES CCCN(CCC)C1CCc2ccc3cc[nH]c3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)16-8-7-14-5-6-15-9-10-19-18(15)17(14)13-16/h5-6,9-10,16,19H,3-4,7-8,11-13H2,1-2H3
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 145n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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 146n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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 156n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035301
PNG
(CHEMBL71899 | Dipropyl-[1-(2,2,2-trifluoro-ethyl)-...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(CC(F)(F)F)c3c2C1
Show InChI InChI=1S/C20H27F3N2/c1-3-9-25(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-24-18)12-20(21,22)23/h6,8,13,16,24H,3-5,7,9-12H2,1-2H3
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 182n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50037274
PNG
(CHEMBL308143 | Dipropyl-(6,7,8,9-tetrahydro-1H-ben...)
Show SMILES CCCN(CCC)C1CCc2ccc3cc[nH]c3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)16-8-7-14-5-6-15-9-10-19-18(15)17(14)13-16/h5-6,9-10,16,19H,3-4,7-8,11-13H2,1-2H3
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 220n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035306
PNG
((1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1
Show InChI InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3
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 317n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50037271
PNG
(CHEMBL305341 | Dipropyl-(5,6,7,8-tetrahydro-1H-ben...)
Show SMILES CCCN(CCC)C1CCc2cc3cc[nH]c3cc2C1
Show InChI InChI=1S/C18H26N2/c1-3-9-20(10-4-2)17-6-5-14-11-15-7-8-19-18(15)13-16(14)12-17/h7-8,11,13,17,19H,3-6,9-10,12H2,1-2H3
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 350n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035303
PNG
((R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1
Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m1/s1
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 382n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50037275
PNG
((2,3,6,7,8,9-Hexahydro-1H-benzo[g]indol-8-yl)-dipr...)
Show SMILES CCCN(CCC)C1CCc2ccc3CCNc3c2C1
Show InChI InChI=1S/C18H28N2/c1-3-11-20(12-4-2)16-8-7-14-5-6-15-9-10-19-18(15)17(14)13-16/h5-6,16,19H,3-4,7-13H2,1-2H3
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 410n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035328
PNG
((R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C#N)c3c2C1
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3/t16-/m1/s1
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 419n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035326
PNG
(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C#N)c3c2C1
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3
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 439n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50037272
PNG
((R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]c(cc3c2C1)C#N
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-19-18(17(14)12-16)11-15(13-20)21-19/h6,8,11,16,21H,3-5,7,9-10,12H2,1-2H3/t16-/m1/s1
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 538n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50037276
PNG
(8-Dipropylamino-2,3,6,7,8,9-hexahydro-benzo[g]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3CCN(C=O)c3c2C1
Show InChI InChI=1S/C19H28N2O/c1-3-10-20(11-4-2)17-8-7-15-5-6-16-9-12-21(14-22)19(16)18(15)13-17/h5-6,14,17H,3-4,7-13H2,1-2H3
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 550n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50037271
PNG
(CHEMBL305341 | Dipropyl-(5,6,7,8-tetrahydro-1H-ben...)
Show SMILES CCCN(CCC)C1CCc2cc3cc[nH]c3cc2C1
Show InChI InChI=1S/C18H26N2/c1-3-9-20(10-4-2)17-6-5-14-11-15-7-8-19-18(15)13-16(14)12-17/h7-8,11,13,17,19H,3-6,9-10,12H2,1-2H3
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 570n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50037275
PNG
((2,3,6,7,8,9-Hexahydro-1H-benzo[g]indol-8-yl)-dipr...)
Show SMILES CCCN(CCC)C1CCc2ccc3CCNc3c2C1
Show InChI InChI=1S/C18H28N2/c1-3-11-20(12-4-2)16-8-7-14-5-6-15-9-10-19-18(15)17(14)13-16/h5-6,16,19H,3-4,7-13H2,1-2H3
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 650n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50037277
PNG
(7-Dipropylamino-5,6,7,8-tetrahydro-1H-benzo[f]indo...)
Show SMILES CCCN(CCC)C1CCc2cc3c(C=O)c[nH]c3cc2C1
Show InChI InChI=1S/C19H26N2O/c1-3-7-21(8-4-2)17-6-5-14-10-18-16(13-22)12-20-19(18)11-15(14)9-17/h10-13,17,20H,3-9H2,1-2H3
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 700n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035301
PNG
(CHEMBL71899 | Dipropyl-[1-(2,2,2-trifluoro-ethyl)-...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(CC(F)(F)F)c3c2C1
Show InChI InChI=1S/C20H27F3N2/c1-3-9-25(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-24-18)12-20(21,22)23/h6,8,13,16,24H,3-5,7,9-12H2,1-2H3
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 796n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
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 1.36E+3n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50037273
PNG
(CHEMBL110032 | Dipropyl-[3-(2,2,2-trifluoro-ethyl)...)
Show SMILES CCCN(CCC)C1CCc2ccc3c(CC(F)(F)F)c[nH]c3c2C1
Show InChI InChI=1S/C20H27F3N2/c1-3-9-25(10-4-2)16-7-5-14-6-8-17-15(12-20(21,22)23)13-24-19(17)18(14)11-16/h6,8,13,16,24H,3-5,7,9-12H2,1-2H3
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 2.33E+3n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50020222
PNG
((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)
Show SMILES CCCN(CCC)C1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3
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 2.81E+3n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035305
PNG
((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1
Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m0/s1
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 3.59E+3n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50037277
PNG
(7-Dipropylamino-5,6,7,8-tetrahydro-1H-benzo[f]indo...)
Show SMILES CCCN(CCC)C1CCc2cc3c(C=O)c[nH]c3cc2C1
Show InChI InChI=1S/C19H26N2O/c1-3-7-21(8-4-2)17-6-5-14-10-18-16(13-22)12-20-19(18)11-15(14)9-17/h10-13,17,20H,3-9H2,1-2H3
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 4.72E+3n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50037278
PNG
(8-Dipropylamino-6,7,8,9-tetrahydro-1H-benzo[g]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3c(C=O)c[nH]c3c2C1
Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-17-15(13-22)12-20-19(17)18(14)11-16/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3
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 6.72E+3n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50035324
PNG
((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C#N)c3c2C1
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3/t16-/m0/s1
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 8.02E+3n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50037273
PNG
(CHEMBL110032 | Dipropyl-[3-(2,2,2-trifluoro-ethyl)...)
Show SMILES CCCN(CCC)C1CCc2ccc3c(CC(F)(F)F)c[nH]c3c2C1
Show InChI InChI=1S/C20H27F3N2/c1-3-9-25(10-4-2)16-7-5-14-6-8-17-15(12-20(21,22)23)13-24-19(17)18(14)11-16/h6,8,13,16,24H,3-5,7,9-12H2,1-2H3
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 8.80E+3n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50037278
PNG
(8-Dipropylamino-6,7,8,9-tetrahydro-1H-benzo[g]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3c(C=O)c[nH]c3c2C1
Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-17-15(13-22)12-20-19(17)18(14)11-16/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3
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>1.60E+4n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50037276
PNG
(8-Dipropylamino-2,3,6,7,8,9-hexahydro-benzo[g]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3CCN(C=O)c3c2C1
Show InChI InChI=1S/C19H28N2O/c1-3-10-20(11-4-2)17-8-7-15-5-6-16-9-12-21(14-22)19(16)18(15)13-17/h5-6,14,17H,3-4,7-13H2,1-2H3
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>1.60E+4n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-spiperone from D2 receptor

J Med Chem 37: 3263-73 (1994)


BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%