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PubMed code 7932563

Compile data set for download or QSAR
Found 60 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037393
PNG
(5,7-Diamino-2-(3-amino-phenyl)-6-hydroxy-chromen-4...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2c(N)c(O)c(N)cc2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-2-7(4-8)11-6-10(19)13-12(21-11)5-9(17)15(20)14(13)18/h1-6,20H,16-18H2
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n/an/a 7.80E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037413
PNG
(6-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL1...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)ccc2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-3-1-9(2-4-10)15-8-13(18)12-7-11(17)5-6-14(12)19-15/h1-8H,16-17H2
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n/an/a 8.70E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037408
PNG
(6-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)c(O)cc2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2
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n/an/a 1.41E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037395
PNG
(5,7-Diamino-2-(4-amino-phenyl)-6-hydroxy-chromen-4...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2c(N)c(O)c(N)cc2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-7(2-4-8)11-6-10(19)13-12(21-11)5-9(17)15(20)14(13)18/h1-6,20H,16-18H2
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n/an/a 1.80E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037413
PNG
(6-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL1...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)ccc2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-3-1-9(2-4-10)15-8-13(18)12-7-11(17)5-6-14(12)19-15/h1-8H,16-17H2
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n/an/a 2.88E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037393
PNG
(5,7-Diamino-2-(3-amino-phenyl)-6-hydroxy-chromen-4...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2c(N)c(O)c(N)cc2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-2-7(4-8)11-6-10(19)13-12(21-11)5-9(17)15(20)14(13)18/h1-6,20H,16-18H2
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n/an/a 3.84E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037393
PNG
(5,7-Diamino-2-(3-amino-phenyl)-6-hydroxy-chromen-4...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2c(N)c(O)c(N)cc2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-2-7(4-8)11-6-10(19)13-12(21-11)5-9(17)15(20)14(13)18/h1-6,20H,16-18H2
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n/an/a 4.60E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037410
PNG
(8-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL3...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cccc(N)c2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-6-4-9(5-7-10)14-8-13(18)11-2-1-3-12(17)15(11)19-14/h1-8H,16-17H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037396
PNG
(8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one...)
Show SMILES COc1ccc(N)c2oc(cc(=O)c12)-c1ccc(N)cc1
Show InChI InChI=1S/C16H14N2O3/c1-20-13-7-6-11(18)16-15(13)12(19)8-14(21-16)9-2-4-10(17)5-3-9/h2-8H,17-18H2,1H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037408
PNG
(6-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)c(O)cc2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037405
PNG
(6-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(O)c2c(ccc(N)c2=O)o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-11(18)14-12(20-13)6-5-10(17)15(14)19/h1-7,18H,16-17H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037392
PNG
(8-Amino-2-(3-amino-phenyl)-6-methoxy-chromen-4-one...)
Show SMILES COc1cc(N)c2oc(cc(=O)c2c1)-c1cccc(N)c1
Show InChI InChI=1S/C16H14N2O3/c1-20-11-6-12-14(19)8-15(21-16(12)13(18)7-11)9-3-2-4-10(17)5-9/h2-8H,17-18H2,1H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037402
PNG
(8-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2c(O)ccc(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-12(19)14-11(18)6-5-10(17)15(14)20-13/h1-7,18H,16-17H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037395
PNG
(5,7-Diamino-2-(4-amino-phenyl)-6-hydroxy-chromen-4...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2c(N)c(O)c(N)cc2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-7(2-4-8)11-6-10(19)13-12(21-11)5-9(17)15(20)14(13)18/h1-6,20H,16-18H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037399
PNG
(6-Amino-2-(3-amino-phenyl)-chromen-4-one | CHEMBL1...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)ccc2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-3-1-2-9(6-10)15-8-13(18)12-7-11(17)4-5-14(12)19-15/h1-8H,16-17H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037407
PNG
(8-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2ccc(O)c(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-12(19)10-5-6-11(18)14(17)15(10)20-13/h1-7,18H,16-17H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037401
PNG
(8-Amino-2-(4-amino-phenyl)-6-methoxy-chromen-4-one...)
Show SMILES COc1cc(N)c2oc(cc(=O)c2c1)-c1ccc(N)cc1
Show InChI InChI=1S/C16H14N2O3/c1-20-11-6-12-14(19)8-15(21-16(12)13(18)7-11)9-2-4-10(17)5-3-9/h2-8H,17-18H2,1H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037397
PNG
(6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)c(O)cc2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-2-8(4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037406
PNG
(8-Amino-2-(4-amino-phenyl)-6-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(O)cc(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)14-7-13(19)11-5-10(18)6-12(17)15(11)20-14/h1-7,18H,16-17H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037409
PNG
(6,8-Diamino-2-(4-amino-phenyl)-7-hydroxy-chromen-4...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)c(O)c(N)c2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-7(2-4-8)12-6-11(19)9-5-10(17)14(20)13(18)15(9)21-12/h1-6,20H,16-18H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50037394
PNG
(6,8-Diamino-2-(4-amino-phenyl)-chromen-4-one | CHE...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)cc(N)c2o1
Show InChI InChI=1S/C15H13N3O2/c16-9-3-1-8(2-4-9)14-7-13(19)11-5-10(17)6-12(18)15(11)20-14/h1-7H,16-18H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037392
PNG
(8-Amino-2-(3-amino-phenyl)-6-methoxy-chromen-4-one...)
Show SMILES COc1cc(N)c2oc(cc(=O)c2c1)-c1cccc(N)c1
Show InChI InChI=1S/C16H14N2O3/c1-20-11-6-12-14(19)8-15(21-16(12)13(18)7-11)9-3-2-4-10(17)5-9/h2-8H,17-18H2,1H3
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n/an/a 5.60E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037409
PNG
(6,8-Diamino-2-(4-amino-phenyl)-7-hydroxy-chromen-4...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)c(O)c(N)c2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-7(2-4-8)12-6-11(19)9-5-10(17)14(20)13(18)15(9)21-12/h1-6,20H,16-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037410
PNG
(8-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL3...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cccc(N)c2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-6-4-9(5-7-10)14-8-13(18)11-2-1-3-12(17)15(11)19-14/h1-8H,16-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037394
PNG
(6,8-Diamino-2-(4-amino-phenyl)-chromen-4-one | CHE...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)cc(N)c2o1
Show InChI InChI=1S/C15H13N3O2/c16-9-3-1-8(2-4-9)14-7-13(19)11-5-10(17)6-12(18)15(11)20-14/h1-7H,16-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037392
PNG
(8-Amino-2-(3-amino-phenyl)-6-methoxy-chromen-4-one...)
Show SMILES COc1cc(N)c2oc(cc(=O)c2c1)-c1cccc(N)c1
Show InChI InChI=1S/C16H14N2O3/c1-20-11-6-12-14(19)8-15(21-16(12)13(18)7-11)9-3-2-4-10(17)5-9/h2-8H,17-18H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037397
PNG
(6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)c(O)cc2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-2-8(4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037396
PNG
(8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one...)
Show SMILES COc1ccc(N)c2oc(cc(=O)c12)-c1ccc(N)cc1
Show InChI InChI=1S/C16H14N2O3/c1-20-13-7-6-11(18)16-15(13)12(19)8-14(21-16)9-2-4-10(17)5-3-9/h2-8H,17-18H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037405
PNG
(6-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(O)c2c(ccc(N)c2=O)o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-11(18)14-12(20-13)6-5-10(17)15(14)19/h1-7,18H,16-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037401
PNG
(8-Amino-2-(4-amino-phenyl)-6-methoxy-chromen-4-one...)
Show SMILES COc1cc(N)c2oc(cc(=O)c2c1)-c1ccc(N)cc1
Show InChI InChI=1S/C16H14N2O3/c1-20-11-6-12-14(19)8-15(21-16(12)13(18)7-11)9-2-4-10(17)5-3-9/h2-8H,17-18H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037395
PNG
(5,7-Diamino-2-(4-amino-phenyl)-6-hydroxy-chromen-4...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2c(N)c(O)c(N)cc2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-7(2-4-8)11-6-10(19)13-12(21-11)5-9(17)15(20)14(13)18/h1-6,20H,16-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037402
PNG
(8-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2c(O)ccc(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-12(19)14-11(18)6-5-10(17)15(14)20-13/h1-7,18H,16-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037407
PNG
(8-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2ccc(O)c(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-12(19)10-5-6-11(18)14(17)15(10)20-13/h1-7,18H,16-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037406
PNG
(8-Amino-2-(4-amino-phenyl)-6-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(O)cc(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)14-7-13(19)11-5-10(18)6-12(17)15(11)20-14/h1-7,18H,16-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50037399
PNG
(6-Amino-2-(3-amino-phenyl)-chromen-4-one | CHEMBL1...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)ccc2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-3-1-2-9(6-10)15-8-13(18)12-7-11(17)4-5-14(12)19-15/h1-8H,16-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037413
PNG
(6-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL1...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)ccc2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-3-1-9(2-4-10)15-8-13(18)12-7-11(17)5-6-14(12)19-15/h1-8H,16-17H2
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n/an/a 1.03E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037394
PNG
(6,8-Diamino-2-(4-amino-phenyl)-chromen-4-one | CHE...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)cc(N)c2o1
Show InChI InChI=1S/C15H13N3O2/c16-9-3-1-8(2-4-9)14-7-13(19)11-5-10(17)6-12(18)15(11)20-14/h1-7H,16-18H2
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n/an/a 1.06E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037406
PNG
(8-Amino-2-(4-amino-phenyl)-6-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(O)cc(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)14-7-13(19)11-5-10(18)6-12(17)15(11)20-14/h1-7,18H,16-17H2
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n/an/a 1.17E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037410
PNG
(8-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL3...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cccc(N)c2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-6-4-9(5-7-10)14-8-13(18)11-2-1-3-12(17)15(11)19-14/h1-8H,16-17H2
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n/an/a 1.23E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037408
PNG
(6-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)c(O)cc2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2
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n/an/a 1.41E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037399
PNG
(6-Amino-2-(3-amino-phenyl)-chromen-4-one | CHEMBL1...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)ccc2o1
Show InChI InChI=1S/C15H12N2O2/c16-10-3-1-2-9(6-10)15-8-13(18)12-7-11(17)4-5-14(12)19-15/h1-8H,16-17H2
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n/an/a 2.00E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037405
PNG
(6-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(O)c2c(ccc(N)c2=O)o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-11(18)14-12(20-13)6-5-10(17)15(14)19/h1-7,18H,16-17H2
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n/an/a 2.23E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037402
PNG
(8-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2c(O)ccc(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-12(19)14-11(18)6-5-10(17)15(14)20-13/h1-7,18H,16-17H2
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n/an/a 3.26E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037407
PNG
(8-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2ccc(O)c(N)c2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-8(2-4-9)13-7-12(19)10-5-6-11(18)14(17)15(10)20-13/h1-7,18H,16-17H2
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n/an/a 3.28E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037401
PNG
(8-Amino-2-(4-amino-phenyl)-6-methoxy-chromen-4-one...)
Show SMILES COc1cc(N)c2oc(cc(=O)c2c1)-c1ccc(N)cc1
Show InChI InChI=1S/C16H14N2O3/c1-20-11-6-12-14(19)8-15(21-16(12)13(18)7-11)9-2-4-10(17)5-3-9/h2-8H,17-18H2,1H3
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n/an/a 3.82E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037397
PNG
(6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one...)
Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)c(O)cc2o1
Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-2-8(4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2
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n/an/a 5.02E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037409
PNG
(6,8-Diamino-2-(4-amino-phenyl)-7-hydroxy-chromen-4...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)c(O)c(N)c2o1
Show InChI InChI=1S/C15H13N3O3/c16-8-3-1-7(2-4-8)12-6-11(19)9-5-10(17)14(20)13(18)15(9)21-12/h1-6,20H,16-18H2
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n/an/a 7.54E+5n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037411
PNG
(7-Hydroxy-6,8-dinitro-2-(4-nitro-phenyl)-chromen-4...)
Show SMILES [O-]c1cc(oc2c([N+]([O-])=O)c(=[OH+])c(cc12)[N+]([O-])=O)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H7N3O9/c19-11-6-12(7-1-3-8(4-2-7)16(21)22)27-15-9(11)5-10(17(23)24)14(20)13(15)18(25)26/h1-6,19H
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n/an/a 1.57E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037396
PNG
(8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one...)
Show SMILES COc1ccc(N)c2oc(cc(=O)c12)-c1ccc(N)cc1
Show InChI InChI=1S/C16H14N2O3/c1-20-13-7-6-11(18)16-15(13)12(19)8-14(21-16)9-2-4-10(17)5-3-9/h2-8H,17-18H2,1H3
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n/an/a 1.62E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037417
PNG
(7-Hydroxy-8-nitro-2-(4-nitro-phenyl)-chromen-4-one...)
Show SMILES [O-]c1cc(oc2c([N+]([O-])=O)c(=[OH+])ccc12)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H8N2O7/c18-11-6-5-10-12(19)7-13(24-15(10)14(11)17(22)23)8-1-3-9(4-2-8)16(20)21/h1-7,19H
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n/an/a 1.88E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037418
PNG
(6-Hydroxy-5,7-dinitro-2-(4-nitro-phenyl)-chromen-4...)
Show SMILES Oc1c(cc2oc(cc(=O)c2c1[N+]([O-])=O)-c1ccc(cc1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C15H7N3O9/c19-10-6-11(7-1-3-8(4-2-7)16(21)22)27-12-5-9(17(23)24)15(20)14(13(10)12)18(25)26/h1-6,20H
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037398
PNG
(6-Nitro-2-(4-nitro-phenyl)-chromen-4-one | CHEMBL6...)
Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc(=O)c2cc(ccc2o1)[N+]([O-])=O
Show InChI InChI=1S/C15H8N2O6/c18-13-8-15(9-1-3-10(4-2-9)16(19)20)23-14-6-5-11(17(21)22)7-12(13)14/h1-8H
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037414
PNG
(6,8-Dinitro-2-(4-nitro-phenyl)-chromen-4-one | CHE...)
Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc(=O)c2cc(cc([N+]([O-])=O)c2o1)[N+]([O-])=O
Show InChI InChI=1S/C15H7N3O8/c19-13-7-14(8-1-3-9(4-2-8)16(20)21)26-15-11(13)5-10(17(22)23)6-12(15)18(24)25/h1-7H
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037412
PNG
(5-Hydroxy-6-nitro-2-(4-nitro-phenyl)-chromen-4-one...)
Show SMILES [O-]c1cc(oc2ccc([N+]([O-])=O)c(=[OH+])c12)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H8N2O7/c18-11-7-13(8-1-3-9(4-2-8)16(20)21)24-12-6-5-10(17(22)23)15(19)14(11)12/h1-7,18H
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037419
PNG
(5-Methoxy-8-nitro-2-(4-nitro-phenyl)-chromen-4-one...)
Show SMILES COc1ccc([N+]([O-])=O)c2oc(cc(=O)c12)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C16H10N2O7/c1-24-13-7-6-11(18(22)23)16-15(13)12(19)8-14(25-16)9-2-4-10(5-3-9)17(20)21/h2-8H,1H3
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037403
PNG
(6-Hydroxy-8-nitro-2-(4-nitro-phenyl)-chromen-4-one...)
Show SMILES Oc1cc([N+]([O-])=O)c2oc(cc(=O)c2c1)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H8N2O7/c18-10-5-11-13(19)7-14(24-15(11)12(6-10)17(22)23)8-1-3-9(4-2-8)16(20)21/h1-7,18H
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037415
PNG
(7-Hydroxy-6-nitro-2-(4-nitro-phenyl)-chromen-4-one...)
Show SMILES [O-]c1cc(oc2cc(=[OH+])c(cc12)[N+]([O-])=O)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H8N2O7/c18-12-6-14(8-1-3-9(4-2-8)16(20)21)24-15-7-13(19)11(17(22)23)5-10(12)15/h1-7,18H
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037404
PNG
(8-Nitro-2-(4-nitro-phenyl)-chromen-4-one | CHEMBL3...)
Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc(=O)c2cccc([N+]([O-])=O)c2o1
Show InChI InChI=1S/C15H8N2O6/c18-13-8-14(9-4-6-10(7-5-9)16(19)20)23-15-11(13)2-1-3-12(15)17(21)22/h1-8H
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037400
PNG
(5-Hydroxy-8-nitro-2-(4-nitro-phenyl)-chromen-4-one...)
Show SMILES [O-]c1cc(oc2c(ccc(=[OH+])c12)[N+]([O-])=O)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H8N2O7/c18-11-6-5-10(17(22)23)15-14(11)12(19)7-13(24-15)8-1-3-9(4-2-8)16(20)21/h1-7,19H
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50037416
PNG
(6-Methoxy-8-nitro-2-(4-nitro-phenyl)-chromen-4-one...)
Show SMILES COc1cc([N+]([O-])=O)c2oc(cc(=O)c2c1)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C16H10N2O7/c1-24-11-6-12-14(19)8-15(25-16(12)13(7-11)18(22)23)9-2-4-10(5-3-9)17(20)21/h2-8H,1H3
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n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP

J Med Chem 37: 3353-62 (1994)


BindingDB Entry DOI: 10.7270/Q2D21WNP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%