Affinity Data by PubMed id=8021912

PubMed code 8021912

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50028880 ((3S,4R)-3-Ethyl-4-phenyl-3-(3-phenyl-propyl)-1-(2,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assay				J Med Chem 37: 1733-6 (1994) BindingDB Entry DOI: 10.7270/Q20P0Z20
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assay				J Med Chem 37: 1733-6 (1994) BindingDB Entry DOI: 10.7270/Q20P0Z20
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50028888 ((3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-(3-phe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assay				J Med Chem 37: 1733-6 (1994) BindingDB Entry DOI: 10.7270/Q20P0Z20
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50028877 ((3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-phenyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assay				J Med Chem 37: 1733-6 (1994) BindingDB Entry DOI: 10.7270/Q20P0Z20
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50028867 ((3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-pro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description The concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity was measured at the dosage by using microsomal ...				J Med Chem 37: 1733-6 (1994) BindingDB Entry DOI: 10.7270/Q20P0Z20
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50038417 ((3R,4R)-3-Ethyl-4-phenyl-3-(3-phenyl-propyl)-1-(2,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assay				J Med Chem 37: 1733-6 (1994) BindingDB Entry DOI: 10.7270/Q20P0Z20
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50028867 ((3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-pro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assay				J Med Chem 37: 1733-6 (1994) BindingDB Entry DOI: 10.7270/Q20P0Z20
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%