BindingDB logo
myBDB logout

PubMed code 8071934

Compile data set for download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50018708
PNG
(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propio...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O
Show InChI InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26-,28+/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.30n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50039966
PNG
(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-22(21(24)16-18-10-4-2-5-11-18)20(17-23-14-8-9-15-23)19-12-6-3-7-13-19/h2-7,10-13,20H,8-9,14-17H2,1H3/t20-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 1.40n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50007344
PNG
((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r|
Show InChI InChI=1S/C21H24Cl2N2O/c1-24(21(26)14-16-9-10-18(22)19(23)13-16)20(15-25-11-5-6-12-25)17-7-3-2-4-8-17/h2-4,7-10,13,20H,5-6,11-12,14-15H2,1H3/t20-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 1.5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50001683
PNG
(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O
Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.80n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50035473
PNG
(2-(3,4-Dichloro-phenyl)-N-[(S)-1-(4-isothiocyanato...)
Show SMILES CN([C@H](CN1CCCC1)c1ccc(cc1)N=C=S)C(=O)Cc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C22H23Cl2N3OS/c1-26(22(28)13-16-4-9-19(23)20(24)12-16)21(14-27-10-2-3-11-27)17-5-7-18(8-6-17)25-15-29/h4-9,12,21H,2-3,10-11,13-14H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.80n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50381677
PNG
(CHEMBL1256748 | U-69593)
Show SMILES CN([C@H]1C[C@@]2(CCCO2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 |r|
Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)20-17-22(11-7-15-26-22)12-10-19(20)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22+/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.10n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50039969
PNG
(2-(2-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-19-11-5-6-12-20(19)23-17-27)21(16-25-13-7-8-14-25)18-9-3-2-4-10-18/h2-6,9-12,21H,7-8,13-16H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.30n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at kappa-opioid receptor sites in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50039968
PNG
(2-(3-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1cccc(c1)N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-18-8-7-11-20(14-18)23-17-27)21(16-25-12-5-6-13-25)19-9-3-2-4-10-19/h2-4,7-11,14,21H,5-6,12-13,15-16H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.30n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50039970
PNG
(2-(4,5-Dichloro-2-isothiocyanato-phenyl)-N-methyl-...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1cc(Cl)c(Cl)cc1N=C=S
Show InChI InChI=1S/C22H23Cl2N3OS/c1-26(21(14-27-9-5-6-10-27)16-7-3-2-4-8-16)22(28)12-17-11-18(23)19(24)13-20(17)25-15-29/h2-4,7-8,11,13,21H,5-6,9-10,12,14H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 9.5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50039967
PNG
(2-(4-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(cc1)N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-18-9-11-20(12-10-18)23-17-27)21(16-25-13-5-6-14-25)19-7-3-2-4-8-19/h2-4,7-12,21H,5-6,13-16H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 14n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50018708
PNG
(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propio...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O
Show InChI InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26-,28+/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 73n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50039968
PNG
(2-(3-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1cccc(c1)N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-18-8-7-11-20(14-18)23-17-27)21(16-25-12-5-6-13-25)19-9-3-2-4-10-19/h2-4,7-11,14,21H,5-6,12-13,15-16H2,1H3/t21-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 144n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50007344
PNG
((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r|
Show InChI InChI=1S/C21H24Cl2N2O/c1-24(21(26)14-16-9-10-18(22)19(23)13-16)20(15-25-11-5-6-12-25)17-7-3-2-4-8-17/h2-4,7-10,13,20H,5-6,11-12,14-15H2,1H3/t20-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 150n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50039967
PNG
(2-(4-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(cc1)N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-18-9-11-20(12-10-18)23-17-27)21(16-25-13-5-6-14-25)19-7-3-2-4-8-19/h2-4,7-12,21H,5-6,13-16H2,1H3/t21-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 150n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50007344
PNG
((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r|
Show InChI InChI=1S/C21H24Cl2N2O/c1-24(21(26)14-16-9-10-18(22)19(23)13-16)20(15-25-11-5-6-12-25)17-7-3-2-4-8-17/h2-4,7-10,13,20H,5-6,11-12,14-15H2,1H3/t20-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 600n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50018708
PNG
(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propio...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O
Show InChI InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26-,28+/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 600n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50039967
PNG
(2-(4-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(cc1)N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-18-9-11-20(12-10-18)23-17-27)21(16-25-13-5-6-14-25)19-7-3-2-4-8-19/h2-4,7-12,21H,5-6,13-16H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 730n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50039969
PNG
(2-(2-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-19-11-5-6-12-20(19)23-17-27)21(16-25-13-7-8-14-25)18-9-3-2-4-10-18/h2-6,9-12,21H,7-8,13-16H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50039966
PNG
(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-22(21(24)16-18-10-4-2-5-11-18)20(17-23-14-8-9-15-23)19-12-6-3-7-13-19/h2-7,10-13,20H,8-9,14-17H2,1H3/t20-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50035473
PNG
(2-(3,4-Dichloro-phenyl)-N-[(S)-1-(4-isothiocyanato...)
Show SMILES CN([C@H](CN1CCCC1)c1ccc(cc1)N=C=S)C(=O)Cc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C22H23Cl2N3OS/c1-26(22(28)13-16-4-9-19(23)20(24)12-16)21(14-27-10-2-3-11-27)17-5-7-18(8-6-17)25-15-29/h4-9,12,21H,2-3,10-11,13-14H2,1H3/t21-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50001683
PNG
(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O
Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50001683
PNG
(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O
Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50039966
PNG
(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-22(21(24)16-18-10-4-2-5-11-18)20(17-23-14-8-9-15-23)19-12-6-3-7-13-19/h2-7,10-13,20H,8-9,14-17H2,1H3/t20-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50035473
PNG
(2-(3,4-Dichloro-phenyl)-N-[(S)-1-(4-isothiocyanato...)
Show SMILES CN([C@H](CN1CCCC1)c1ccc(cc1)N=C=S)C(=O)Cc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C22H23Cl2N3OS/c1-26(22(28)13-16-4-9-19(23)20(24)12-16)21(14-27-10-2-3-11-27)17-5-7-18(8-6-17)25-15-29/h4-9,12,21H,2-3,10-11,13-14H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50039969
PNG
(2-(2-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-19-11-5-6-12-20(19)23-17-27)21(16-25-13-7-8-14-25)18-9-3-2-4-10-18/h2-6,9-12,21H,7-8,13-16H2,1H3/t21-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.06E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50039970
PNG
(2-(4,5-Dichloro-2-isothiocyanato-phenyl)-N-methyl-...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1cc(Cl)c(Cl)cc1N=C=S
Show InChI InChI=1S/C22H23Cl2N3OS/c1-26(21(14-27-9-5-6-10-27)16-7-3-2-4-8-16)22(28)12-17-11-18(23)19(24)13-20(17)25-15-29/h2-4,7-8,11,13,21H,5-6,9-10,12,14H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.25E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50039970
PNG
(2-(4,5-Dichloro-2-isothiocyanato-phenyl)-N-methyl-...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1cc(Cl)c(Cl)cc1N=C=S
Show InChI InChI=1S/C22H23Cl2N3OS/c1-26(21(14-27-9-5-6-10-27)16-7-3-2-4-8-16)22(28)12-17-11-18(23)19(24)13-20(17)25-15-29/h2-4,7-8,11,13,21H,5-6,9-10,12,14H2,1H3/t21-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50381677
PNG
(CHEMBL1256748 | U-69593)
Show SMILES CN([C@H]1C[C@@]2(CCCO2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 |r|
Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)20-17-22(11-7-15-26-22)12-10-19(20)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22+/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.76E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50381677
PNG
(CHEMBL1256748 | U-69593)
Show SMILES CN([C@H]1C[C@@]2(CCCO2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 |r|
Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)20-17-22(11-7-15-26-22)12-10-19(20)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50039968
PNG
(2-(3-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Show SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1cccc(c1)N=C=S
Show InChI InChI=1S/C22H25N3OS/c1-24(22(26)15-18-8-7-11-20(14-18)23-17-27)21(16-25-12-5-6-13-25)19-9-3-2-4-10-19/h2-4,7-11,14,21H,5-6,12-13,15-16H2,1H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 5.10E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane

J Med Chem 37: 2856-64 (1994)


BindingDB Entry DOI: 10.7270/Q2513ZVF
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%