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PubMed code 8126693

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)
BDBM50040469
PNG
(2,3-Diphenyl-6-thia-1,4-diaza-bicyclo[3.1.0]hexa-2...)
Show SMILES S1c2nc(c(-c3ccccc3)n12)-c1ccccc1
Show InChI InChI=1S/C15H10N2S/c1-3-7-11(8-4-1)13-14(17-15(16-13)18-17)12-9-5-2-6-10-12/h1-10H
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 18n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was evaluated for the Acyl coenzyme A:cholesterol acyltransferase inhibition using microsomes isolated from the livers of cholesterol fed ra...


J Med Chem 37: 560-2 (1994)


BindingDB Entry DOI: 10.7270/Q2542MN8
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Rattus norvegicus)
BDBM50040468
PNG
(2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...)
Show SMILES CC(C)c1cccc(C(C)C)c1OC(=O)[N-]S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C
Show InChI InChI=1S/C25H35NO5S/c1-15(2)19-11-9-12-20(16(3)4)23(19)30-25(27)26-32(28,29)31-24-21(17(5)6)13-10-14-22(24)18(7)8/h9-18H,1-8H3,(H,26,27)/p-1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was evaluated for the Acyl coenzyme A:cholesterol acyltransferase inhibition using microsomes isolated from the livers of cholesterol fed ra...


J Med Chem 37: 560-2 (1994)


BindingDB Entry DOI: 10.7270/Q2542MN8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%