Affinity Data by PubMed id=8126697

PubMed code 8126697

Found 30 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	0.00720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against delta1 opioid receptor using [3H]DPDPE ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50040487 (17-(cyclopropylmethyl)4,5-alpha-epoxy-3,14-dihydro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against delta opioid receptor using [3H]naltridole ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50040485 (15-benzyl-4-cyclopropylmethyl-10,17-dihydroxy-(1S,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 1 using [3H]DPDPE ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50040483 (4-cyclopropylmethyl-10,17-dihydroxy-15-phenyl-(1S,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 2 using [3H]DSLET ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50040484 (14-anilino-4-cyclopropylmethyl-(13R,14R,17S)-12-ox...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against mu opioid receptor using [3H]DAMGO ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50040484 (14-anilino-4-cyclopropylmethyl-(13R,14R,17S)-12-ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 1 using [3H]DPDPE ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50056628 (4-cyclopropylmethyl-10,17-dihydroxy-15-[1-phenyl-(...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 1 using [3H]DPDPE ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50040483 (4-cyclopropylmethyl-10,17-dihydroxy-15-phenyl-(1S,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 1 using [3H]DPDPE ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50040483 (4-cyclopropylmethyl-10,17-dihydroxy-15-phenyl-(1S,...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against mu opioid receptor using [3H]DAMGO ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50040484 (14-anilino-4-cyclopropylmethyl-(13R,14R,17S)-12-ox...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against mu opioid receptor using [3H]DAMGO ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50040487 (17-(cyclopropylmethyl)4,5-alpha-epoxy-3,14-dihydro...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against mu opioid receptor using [3H]DAMGO ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50040484 (14-anilino-4-cyclopropylmethyl-(13R,14R,17S)-12-ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 2 using [3H]DSLET ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50056628 (4-cyclopropylmethyl-10,17-dihydroxy-15-[1-phenyl-(...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 2 using [3H]DSLET ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50056628 (4-cyclopropylmethyl-10,17-dihydroxy-15-[1-phenyl-(...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against mu opioid receptor using [3H]DAMGO ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50040484 (14-anilino-4-cyclopropylmethyl-(13R,14R,17S)-12-ox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50040484 (14-anilino-4-cyclopropylmethyl-(13R,14R,17S)-12-ox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50040484 (14-anilino-4-cyclopropylmethyl-(13R,14R,17S)-12-ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 1 using [3H]DPDPE ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50040482 (17-(cyclopropylmethyl)-6,7-didehydro-4,5-alpha-epo...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against mu opioid receptor using [3H]DAMGO ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50040485 (15-benzyl-4-cyclopropylmethyl-10,17-dihydroxy-(1S,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50040484 (14-anilino-4-cyclopropylmethyl-(13R,14R,17S)-12-ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 2 using [3H]DSLET ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50040485 (15-benzyl-4-cyclopropylmethyl-10,17-dihydroxy-(1S,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 2 using [3H]DSLET ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50040487 (17-(cyclopropylmethyl)4,5-alpha-epoxy-3,14-dihydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50040485 (15-benzyl-4-cyclopropylmethyl-10,17-dihydroxy-(1S,...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against mu opioid receptor using [3H]DAMGO ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against mu opioid receptor using [3H]DAMGO ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50040482 (17-(cyclopropylmethyl)-6,7-didehydro-4,5-alpha-epo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 2 using [3H]DSLET ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50040482 (17-(cyclopropylmethyl)-6,7-didehydro-4,5-alpha-epo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50040483 (4-cyclopropylmethyl-10,17-dihydroxy-15-phenyl-(1S,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50056628 (4-cyclopropylmethyl-10,17-dihydroxy-15-[1-phenyl-(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50040482 (17-(cyclopropylmethyl)-6,7-didehydro-4,5-alpha-epo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for binding activity against Opioid receptor delta 1 using [3H]DPDPE ligand				J Med Chem 37: 579-85 (1994) BindingDB Entry DOI: 10.7270/Q2CF9QRG
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%