Affinity Data by PubMed id=8254612

PubMed code 8254612

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021127 (2-(1-Carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-ben...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition against neutral endopeptidase (NEP) from rat kidney				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM21641 (2-(2-benzyl-3-sulfanylpropanamido)acetic acid \| CH...) Show SMILES OC(=O)CNC(=O)C(CS)Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition against neutral endopeptidase (NEP) from rat kidney				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50042838 (6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotridecane...) Show SMILES OC(=O)[C@@H]1CSCCCCCCCC(CS)C(=O)N1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition of angiotensin converting enzyme from rabbit lung				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50042838 (6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotridecane...) Show SMILES OC(=O)[C@@H]1CSCCCCCCCC(CS)C(=O)N1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition of angiotensin converting enzyme from rabbit lung				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50042838 (6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotridecane...) Show SMILES OC(=O)[C@@H]1CSCCCCCCCC(CS)C(=O)N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition against neutral endopeptidase (NEP) from rat kidney				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50042838 (6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotridecane...) Show SMILES OC(=O)[C@@H]1CSCCCCCCCC(CS)C(=O)N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition against angiotensin converting enzyme (ACE) from rabbit lung				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50042837 (6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotetradeca...) Show SMILES OC(=O)[C@@H]1CSCCCCCCCCC(CS)C(=O)N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition against neutral endopeptidase (NEP) from rat kidney				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50042837 (6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotetradeca...) Show SMILES OC(=O)[C@@H]1CSCCCCCCCCC(CS)C(=O)N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition against neutral endopeptidase (NEP) from rat kidney				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50042837 (6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotetradeca...) Show SMILES OC(=O)[C@@H]1CSCCCCCCCCC(CS)C(=O)N1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition against neutral endopeptidase (NEP) from rat kidney				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50042837 (6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotetradeca...) Show SMILES OC(=O)[C@@H]1CSCCCCCCCCC(CS)C(=O)N1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Tested in vitro for the inhibition of angiotensin converting enzyme from rabbit lung				J Med Chem 36: 3829-33 (1994) BindingDB Entry DOI: 10.7270/Q2125RRG
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%