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PubMed code 8410989

Compile data set for download or QSAR
Found 58 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039822
PNG
(1-(2-Cyclohexyl-ethyl)-4-(2,3-dihydro-benzo[1,4]di...)
Show SMILES C(CN1CCN(CC1)c1cccc2OCCOc12)C1CCCCC1
Show InChI InChI=1S/C20H30N2O2/c1-2-5-17(6-3-1)9-10-21-11-13-22(14-12-21)18-7-4-8-19-20(18)24-16-15-23-19/h4,7-8,17H,1-3,5-6,9-16H2
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 0.25n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039819
PNG
(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-hexyl-pipe...)
Show SMILES CCCCCCN1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C18H28N2O2/c1-2-3-4-5-9-19-10-12-20(13-11-19)16-7-6-8-17-18(16)22-15-14-21-17/h6-8H,2-5,9-15H2,1H3
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 0.5n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039805
PNG
(1-Benzofuran-7-yl-4-hexyl-piperazine | CHEMBL27558)
Show SMILES CCCCCCN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C18H26N2O/c1-2-3-4-5-10-19-11-13-20(14-12-19)17-8-6-7-16-9-15-21-18(16)17/h6-9,15H,2-5,10-14H2,1H3
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 0.540n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039796
PNG
(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-octyl-pipe...)
Show SMILES CCCCCCCCN1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C20H32N2O2/c1-2-3-4-5-6-7-11-21-12-14-22(15-13-21)18-9-8-10-19-20(18)24-17-16-23-19/h8-10H,2-7,11-17H2,1H3
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 0.610n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039795
PNG
(1-Benzofuran-7-yl-4-pentyl-piperazine | CHEMBL2683...)
Show SMILES CCCCCN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C17H24N2O/c1-2-3-4-9-18-10-12-19(13-11-18)16-7-5-6-15-8-14-20-17(15)16/h5-8,14H,2-4,9-13H2,1H3
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 0.810n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039826
PNG
(1-Decyl-4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-pipe...)
Show SMILES CCCCCCCCCCN1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C22H36N2O2/c1-2-3-4-5-6-7-8-9-13-23-14-16-24(17-15-23)20-11-10-12-21-22(20)26-19-18-25-21/h10-12H,2-9,13-19H2,1H3
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 1n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039832
PNG
(1-Benzofuran-7-yl-4-octyl-piperazine | CHEMBL26988)
Show SMILES CCCCCCCCN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C20H30N2O/c1-2-3-4-5-6-7-12-21-13-15-22(16-14-21)19-10-8-9-18-11-17-23-20(18)19/h8-11,17H,2-7,12-16H2,1H3
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 1.70n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039806
PNG
(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-pentyl-pip...)
Show SMILES CCCCCN1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C17H26N2O2/c1-2-3-4-8-18-9-11-19(12-10-18)15-6-5-7-16-17(15)21-14-13-20-16/h5-7H,2-4,8-14H2,1H3
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 2.20n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005135
PNG
(1-(3-Chloro-phenyl)-4-hexyl-piperazine | CHEMBL279...)
Show SMILES CCCCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C16H25ClN2/c1-2-3-4-5-9-18-10-12-19(13-11-18)16-8-6-7-15(17)14-16/h6-8,14H,2-5,9-13H2,1H3
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 2.70n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
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 2.80n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005140
PNG
(1-(3-Chloro-phenyl)-4-pentyl-piperazine | CHEMBL27...)
Show SMILES CCCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C15H23ClN2/c1-2-3-4-8-17-9-11-18(12-10-17)15-7-5-6-14(16)13-15/h5-7,13H,2-4,8-12H2,1H3
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 5.5n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate (experi...

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005127
PNG
(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12
Show InChI InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2
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 5.5n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039809
PNG
(1-Benzofuran-7-yl-4-butyl-piperazine | CHEMBL28082...)
Show SMILES CCCCN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C16H22N2O/c1-2-3-8-17-9-11-18(12-10-17)15-6-4-5-14-7-13-19-16(14)15/h4-7,13H,2-3,8-12H2,1H3
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 5.90n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039816
PNG
(1-Benzofuran-7-yl-4-cyclohexylmethyl-piperazine | ...)
Show SMILES C(C1CCCCC1)N1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C19H26N2O/c1-2-5-16(6-3-1)15-20-10-12-21(13-11-20)18-8-4-7-17-9-14-22-19(17)18/h4,7-9,14,16H,1-3,5-6,10-13,15H2
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 7.70n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005140
PNG
(1-(3-Chloro-phenyl)-4-pentyl-piperazine | CHEMBL27...)
Show SMILES CCCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C15H23ClN2/c1-2-3-4-8-17-9-11-18(12-10-17)15-7-5-6-14(16)13-15/h5-7,13H,2-4,8-12H2,1H3
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 7.80n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate (experim...

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039804
PNG
(1-Benzofuran-7-yl-4-decyl-piperazine | CHEMBL26355)
Show SMILES CCCCCCCCCCN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C22H34N2O/c1-2-3-4-5-6-7-8-9-14-23-15-17-24(18-16-23)21-12-10-11-20-13-19-25-22(20)21/h10-13,19H,2-9,14-18H2,1H3
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 8n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039830
PNG
(1-Benzofuran-7-yl-4-methyl-piperazine | CHEMBL2862...)
Show SMILES CN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C13H16N2O/c1-14-6-8-15(9-7-14)12-4-2-3-11-5-10-16-13(11)12/h2-5,10H,6-9H2,1H3
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 8.10n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039793
PNG
(1-Cyclohexylmethyl-4-(2,3-dihydro-benzo[1,4]dioxin...)
Show SMILES C(C1CCCCC1)N1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C19H28N2O2/c1-2-5-16(6-3-1)15-20-9-11-21(12-10-20)17-7-4-8-18-19(17)23-14-13-22-18/h4,7-8,16H,1-3,5-6,9-15H2
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 11n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005129
PNG
(1-(3-Chloro-phenyl)-4-octyl-piperazine | CHEMBL805...)
Show SMILES CCCCCCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C18H29ClN2/c1-2-3-4-5-6-7-11-20-12-14-21(15-13-20)18-10-8-9-17(19)16-18/h8-10,16H,2-7,11-15H2,1H3
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 11n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039803
PNG
(1-Butyl-4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-pipe...)
Show SMILES CCCCN1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C16H24N2O2/c1-2-3-7-17-8-10-18(11-9-17)14-5-4-6-15-16(14)20-13-12-19-15/h4-6H,2-3,7-13H2,1H3
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 12n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035042
PNG
(1-Benzofuran-7-yl-piperazine | CHEMBL61032)
Show SMILES C1CN(CCN1)c1cccc2ccoc12
Show InChI InChI=1S/C12H14N2O/c1-2-10-4-9-15-12(10)11(3-1)14-7-5-13-6-8-14/h1-4,9,13H,5-8H2
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 13n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005134
PNG
(1-Butyl-4-(3-chloro-phenyl)-piperazine | CHEMBL266...)
Show SMILES CCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C14H21ClN2/c1-2-3-7-16-8-10-17(11-9-16)14-6-4-5-13(15)12-14/h4-6,12H,2-3,7-11H2,1H3
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 18n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039808
PNG
(1-Benzofuran-7-yl-4-cyclopropylmethyl-piperazine |...)
Show SMILES C(C1CC1)N1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C16H20N2O/c1-2-14-6-11-19-16(14)15(3-1)18-9-7-17(8-10-18)12-13-4-5-13/h1-3,6,11,13H,4-5,7-10,12H2
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 20n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039815
PNG
(1-Benzofuran-7-yl-4-ethyl-piperazine | CHEMBL32924...)
Show SMILES CCN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C14H18N2O/c1-2-15-7-9-16(10-8-15)13-5-3-4-12-6-11-17-14(12)13/h3-6,11H,2,7-10H2,1H3
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 23n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039813
PNG
(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-methyl-pip...)
Show SMILES CN1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C13H18N2O2/c1-14-5-7-15(8-6-14)11-3-2-4-12-13(11)17-10-9-16-12/h2-4H,5-10H2,1H3
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 24n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039820
PNG
(1-Benzofuran-7-yl-4-propyl-piperazine | CHEMBL2664...)
Show SMILES CCCN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C15H20N2O/c1-2-7-16-8-10-17(11-9-16)14-5-3-4-13-6-12-18-15(13)14/h3-6,12H,2,7-11H2,1H3
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 29n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50035057
PNG
((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...)
Show SMILES C1CN(CCN1)c1cccc2OCCOc12
Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2
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 40n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039828
PNG
(1-Benzofuran-7-yl-4-isopropyl-piperazine | CHEMBL2...)
Show SMILES CC(C)N1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C15H20N2O/c1-12(2)16-7-9-17(10-8-16)14-5-3-4-13-6-11-18-15(13)14/h3-6,11-12H,7-10H2,1-2H3
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 56n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039823
PNG
(1-Benzofuran-7-yl-4-cyclohexyl-piperazine | CHEMBL...)
Show SMILES C1CCC(CC1)N1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C18H24N2O/c1-2-6-16(7-3-1)19-10-12-20(13-11-19)17-8-4-5-15-9-14-21-18(15)17/h4-5,8-9,14,16H,1-3,6-7,10-13H2
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 64n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039825
PNG
(1-Benzofuran-7-yl-4-isobutyl-piperazine | CHEMBL96...)
Show SMILES CC(C)CN1CCN(CC1)c1cccc2ccoc12
Show InChI InChI=1S/C16H22N2O/c1-13(2)12-17-7-9-18(10-8-17)15-5-3-4-14-6-11-19-16(14)15/h3-6,11,13H,7-10,12H2,1-2H3
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 64n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039831
PNG
(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-ethyl-pipe...)
Show SMILES CCN1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C14H20N2O2/c1-2-15-6-8-16(9-7-15)12-4-3-5-13-14(12)18-11-10-17-13/h3-5H,2,6-11H2,1H3
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 66n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50039817
PNG
(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-propyl-pip...)
Show SMILES CCCN1CCN(CC1)c1cccc2OCCOc12
Show InChI InChI=1S/C15H22N2O2/c1-2-6-16-7-9-17(10-8-16)13-4-3-5-14-15(13)19-12-11-18-14/h3-5H,2,6-12H2,1H3
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 80n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005123
PNG
(1-(3-Chloro-phenyl)-4-propyl-piperazine | 1-(3-Chl...)
Show SMILES CCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C13H19ClN2/c1-2-6-15-7-9-16(10-8-15)13-5-3-4-12(14)11-13/h3-5,11H,2,6-10H2,1H3
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 122n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001915
PNG
(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)
Show SMILES Clc1cccc(c1)N1CCNCC1
Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2
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 143n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate (experi...

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005124
PNG
(1-(3-Chloro-phenyl)-4-methyl-piperazine | CHEMBL26...)
Show SMILES CN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C11H15ClN2/c1-13-5-7-14(8-6-13)11-4-2-3-10(12)9-11/h2-4,9H,5-8H2,1H3
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 152n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005142
PNG
(1-(3-Chloro-phenyl)-4-isopropyl-piperazine | CHEMB...)
Show SMILES CC(C)N1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C13H19ClN2/c1-11(2)15-6-8-16(9-7-15)13-5-3-4-12(14)10-13/h3-5,10-11H,6-9H2,1-2H3
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 159n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001862
PNG
((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Show SMILES COc1ccccc1N1CCNCC1
Show InChI InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
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 170n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001915
PNG
(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)
Show SMILES Clc1cccc(c1)N1CCNCC1
Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2
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 200n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate (experim...

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50005139
PNG
(1-(3-Chloro-phenyl)-4-ethyl-piperazine | CHEMBL413...)
Show SMILES CCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C12H17ClN2/c1-2-14-6-8-15(9-7-14)12-5-3-4-11(13)10-12/h3-5,10H,2,6-9H2,1H3
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 220n/an/an/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231235
PNG
(CHEMBL441636)
Show SMILES CCCCCCCCN1CCC(CC1)(C(=O)OCC)c1ccccc1
Show InChI InChI=1S/C22H35NO2/c1-3-5-6-7-8-12-17-23-18-15-22(16-19-23,21(24)25-4-2)20-13-10-9-11-14-20/h9-11,13-14H,3-8,12,15-19H2,1-2H3
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n/an/a 30n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231227
PNG
(CHEMBL328583)
Show SMILES CCCCCCCN1CCC(CC1)(C(=O)OCC)c1ccccc1
Show InChI InChI=1S/C21H33NO2/c1-3-5-6-7-11-16-22-17-14-21(15-18-22,20(23)24-4-2)19-12-9-8-10-13-19/h8-10,12-13H,3-7,11,14-18H2,1-2H3
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n/an/a 55n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231230
PNG
(CHEMBL328019)
Show SMILES CCCCCCCCCN1CCC(CC1)(C(=O)OCC)c1ccccc1
Show InChI InChI=1S/C23H37NO2/c1-3-5-6-7-8-9-13-18-24-19-16-23(17-20-24,22(25)26-4-2)21-14-11-10-12-15-21/h10-12,14-15H,3-9,13,16-20H2,1-2H3
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n/an/a 150n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231233
PNG
(CHEMBL92960)
Show SMILES CCCCCCN1CCC(CC1)(C(=O)OCC)c1ccccc1
Show InChI InChI=1S/C20H31NO2/c1-3-5-6-10-15-21-16-13-20(14-17-21,19(22)23-4-2)18-11-8-7-9-12-18/h7-9,11-12H,3-6,10,13-17H2,1-2H3
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n/an/a 200n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231240
PNG
(CHEMBL92779)
Show SMILES CCCCCN1CCC(CC1)(C(=O)OCC)c1ccccc1
Show InChI InChI=1S/C19H29NO2/c1-3-5-9-14-20-15-12-19(13-16-20,18(21)22-4-2)17-10-7-6-8-11-17/h6-8,10-11H,3-5,9,12-16H2,1-2H3
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n/an/a 400n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50026752
PNG
(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)
Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1
Show InChI InChI=1S/C15H21NO2/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13/h4-8H,3,9-12H2,1-2H3
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n/an/a 500n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231231
PNG
(CHEMBL92124)
Show SMILES CCCCN1CCC(CC1)(C(=O)OCC)c1ccccc1
Show InChI InChI=1S/C18H27NO2/c1-3-5-13-19-14-11-18(12-15-19,17(20)21-4-2)16-9-7-6-8-10-16/h6-10H,3-5,11-15H2,1-2H3
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n/an/a 900n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231236
PNG
(CHEMBL89961)
Show SMILES CCCN1CCC(CC1)(C(=O)OCC)c1ccccc1
Show InChI InChI=1S/C17H25NO2/c1-3-12-18-13-10-17(11-14-18,16(19)20-4-2)15-8-6-5-7-9-15/h5-9H,3-4,10-14H2,1-2H3
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n/an/a 4.00E+3n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231241
PNG
(CHEMBL285244)
Show SMILES CCOC(=O)C1(CCN(CC)CC1)c1ccccc1
Show InChI InChI=1S/C16H23NO2/c1-3-17-12-10-16(11-13-17,15(18)19-4-2)14-8-6-5-7-9-14/h5-9H,3-4,10-13H2,1-2H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231237
PNG
(CHEBI:6125 | Cetobemidone | Cliradon | Cymidon | K...)
Show SMILES CCC(=O)C1(CCN(C)CC1)c1cccc(O)c1
Show InChI InChI=1S/C15H21NO2/c1-3-14(18)15(7-9-16(2)10-8-15)12-5-4-6-13(17)11-12/h4-6,11,17H,3,7-10H2,1-2H3
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n/an/a 7.00E+3n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor; value ranges from 7-10 uM

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231228
PNG
(CHEMBL96626)
Show SMILES CCCCCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C19H29NO2/c1-3-5-6-12-20-13-10-19(11-14-20,18(22)4-2)16-8-7-9-17(21)15-16/h7-9,15,21H,3-6,10-14H2,1-2H3
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n/an/a 8.00E+3n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate (experim...

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231229
PNG
(CHEMBL440699)
Show SMILES CCCCCCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C20H31NO2/c1-3-5-6-7-13-21-14-11-20(12-15-21,19(23)4-2)17-9-8-10-18(22)16-17/h8-10,16,22H,3-7,11-15H2,1-2H3
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n/an/a 2.00E+4n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50045602
PNG
(1-[1-Heptyl-4-(3-hydroxy-phenyl)-piperidin-4-yl]-p...)
Show SMILES CCCCCCCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C21H33NO2/c1-3-5-6-7-8-14-22-15-12-21(13-16-22,20(24)4-2)18-10-9-11-19(23)17-18/h9-11,17,23H,3-8,12-16H2,1-2H3
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n/an/a 2.00E+4n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231239
PNG
(CHEMBL329911)
Show SMILES CCCCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C18H27NO2/c1-3-5-11-19-12-9-18(10-13-19,17(21)4-2)15-7-6-8-16(20)14-15/h6-8,14,20H,3-5,9-13H2,1-2H3
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n/an/a 5.00E+4n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231243
PNG
(CHEMBL93296)
Show SMILES CCCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C17H25NO2/c1-3-10-18-11-8-17(9-12-18,16(20)4-2)14-6-5-7-15(19)13-14/h5-7,13,19H,3-4,8-12H2,1-2H3
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n/an/a 2.00E+5n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231242
PNG
(CHEMBL92303)
Show SMILES CCCCCCCCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C22H35NO2/c1-3-5-6-7-8-9-15-23-16-13-22(14-17-23,21(25)4-2)19-11-10-12-20(24)18-19/h10-12,18,24H,3-9,13-17H2,1-2H3
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n/an/a 2.00E+5n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231238
PNG
(CHEMBL93306)
Show SMILES CCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C16H23NO2/c1-3-15(19)16(8-10-17(4-2)11-9-16)13-6-5-7-14(18)12-13/h5-7,12,18H,3-4,8-11H2,1-2H3
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n/an/a 4.00E+5n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231244
PNG
(CHEMBL90632)
Show SMILES CCCCCCCCCCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C24H39NO2/c1-3-5-6-7-8-9-10-11-17-25-18-15-24(16-19-25,23(27)4-2)21-13-12-14-22(26)20-21/h12-14,20,26H,3-11,15-19H2,1-2H3
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n/an/a 5.00E+5n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse)-MOUSE)		BDBM50231245
PNG
(CHEMBL92403)
Show SMILES CCCCCCCCCN1CCC(CC1)(C(=O)CC)c1cccc(O)c1
Show InChI InChI=1S/C23H37NO2/c1-3-5-6-7-8-9-10-16-24-17-14-23(15-18-24,22(26)4-2)20-12-11-13-21(25)19-20/h11-13,19,25H,3-10,14-18H2,1-2H3
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n/an/a 7.00E+5n/an/an/an/an/an/a



Solvay Duphar Research Laboratories

Curated by ChEMBL


Assay Description
Tested for displacement of radioligand [3H]-Naloxone from opiate receptor

J Med Chem 36: 2751-60 (1993)


BindingDB Entry DOI: 10.7270/Q2CZ367F
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%