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PubMed code 8426360

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aromatic-L-amino-acid decarboxylase


(Mus musculus)
BDBM50046351
PNG
(2-Amino-2-fluoromethyl-3-(5-hydroxy-1H-indol-3-yl)...)
Show SMILES N[C@@](CF)(Cc1c[nH]c2ccc(O)cc12)C(O)=O
Show InChI InChI=1S/C12H13FN2O3/c13-6-12(14,11(17)18)4-7-5-15-10-2-1-8(16)3-9(7)10/h1-3,5,15-16H,4,6,14H2,(H,17,18)/t12-/m1/s1
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Similars

PubMed
2.43E+4n/an/an/an/an/an/an/an/a



Mayo Clinic and Foundation

Curated by ChEMBL


Assay Description
Dissociation constant (KI) of the compound was evaluated as inhibitor of murine liver aromatic L-amino acid decarboxylase (AADC)


J Med Chem 36: 305-13 (1993)


BindingDB Entry DOI: 10.7270/Q2DV1J0Z
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%