Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50047471 ((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluated | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluated | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50047472 ((R)-N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluated | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 265 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the dopamine receptor D2 at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50456023 (CHEMBL289981) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 437 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluated | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the 5-hydroxytryptamine 1C receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the noradrenergic alpha-1 receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the noradrenergic alpha-2 receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the noradrenergic beta receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50047471 ((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the 5-hydroxytryptamine 2 receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50047472 ((R)-N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the anor-adrenergic alpha-1 receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50047471 ((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the alpha-1 receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the 5-hydroxytryptamine 2 receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50456023 (CHEMBL289981) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research (UK) Curated by ChEMBL | Assay Description In vitro binding affinity towards the noradrenergic alpha-1 receptor at 10 e-6 M | J Med Chem 36: 1509-10 (1993) BindingDB Entry DOI: 10.7270/Q29W0DJH | |||||||||||
More data for this Ligand-Target Pair |