Affinity Data by PubMed id=8568809

PubMed code 8568809

Found 34 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048928 (4-(2,4-Dioxo-1-propyl-1,4-dihydro-2H-pteridin-3-yl...) Show SMILES CCCn1c2nccnc2c(=O)n(CCCC(=O)OCC)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048929 (4-(7-Methyl-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-...) Show SMILES CCCn1c2ncn(C)c2c(=O)n(CCCC(=O)OCC)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048933 (4-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...) Show SMILES CCOC(=O)CCCn1c(=O)n(C)c2ncn(C)c2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048931 (3-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...) Show SMILES CCOC(=O)CCn1c(=O)n(C)c2ncn(C)c2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048924 (5-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...) Show SMILES CCOC(=O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048943 (4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...) Show SMILES CCOC(=O)CCCn1c(=O)n(C)c2nccnc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram \| 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048925 (4-(1-Butyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl)...) Show SMILES CCCCn1c2nccnc2c(=O)n(CCCC(=O)OCC)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048932 (4-(2,4-Dioxo-1-pentyl-1,4-dihydro-2H-pteridin-3-yl...) Show SMILES CCCCCn1c2nccnc2c(=O)n(CCCC(=O)OCC)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048935 (4-(5,7-Dioxo-4-propyl-4,5-dihydro-7H-[1,2,5]thiadi...) Show SMILES CCCn1c2nsnc2c(=O)n(CCCC(=O)OCC)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048920 (4-[2,4-Dioxo-1-(tetrahydro-furan-3-yl)-1,4-dihydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048948 (4-(1-Isobutyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-...) Show SMILES CCOC(=O)CCCn1c(=O)n(CC(C)C)c2nccnc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048938 ((Z)-4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-...) Show SMILES COC(=O)\C=C/Cn1c(=O)n(C)c2nccnc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048942 (4-(4-Methyl-5,7-dioxo-4,5-dihydro-7H-[1,2,5]thiadi...) Show SMILES CCOC(=O)CCCn1c(=O)n(C)c2nsnc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048940 (1-Hexyl-8-hydroxy-3-methyl-3,7,8,9-tetrahydro-puri...) Show SMILES CCCCCCn1c(=O)c2NC(O)Nc2n(C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50010981 ((Ro 20-1724)4-(3-Butoxy-4-methoxy-benzyl)-imidazol...) Show SMILES CCCCOc1cc(CC2CNC(=O)N2)ccc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048939 (4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-...) Show SMILES CCOC(=O)CCCn1c(=O)n(C)c2ccccc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048921 (4-(8-Bromo-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahyd...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048927 (6-Heptyl-4-methyl-4H-[1,2,5]thiadiazolo[3,4-d]pyri...) Show SMILES CCCCCCCn1c(=O)n(C)c2nsnc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM10850 (1-(5-Oxohexyl)theobromine (pentoxifylline) \| 3,7-d...) Show SMILES CC(=O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048945 (4-(8-Mercapto-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetra...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048922 (4-(6,7-Diethyl-1-methyl-2,4-dioxo-1,4-dihydro-2H-p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048934 (4-(1-Benzyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048937 (4-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048923 (4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-...) Show SMILES Cn1c2ccccc2c(=O)n(CCCC(O)=O)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048941 ((3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin-1...) Show SMILES CCOC(=O)Cn1c(=O)n(C)c2ncn(C)c2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048926 (8-Mercapto-3-methyl-3,7-dihydro-purine-2,6-dione \|...) Show SMILES Cn1c2[nH]c(=S)[nH]c2c(=O)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048936 (1-[4-Carboxypropyl]-3,7-Dimethylxanthine (Metaboli...) Show SMILES Cn1cnc2n(C)c(=O)n(CCCC(O)=O)c(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048947 (4-(2,4-Dioxo-1-propyl-1,4-dihydro-2H-pteridin-3-yl...) Show SMILES CCCn1c2nccnc2c(=O)n(CCCC(O)=O)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048949 (4-(1-Methyl-2,4-dioxo-6-phenyl-1,4-dihydro-2H-pter...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048946 (4-(4-Methyl-5,7-dioxo-4,5-dihydro-7H-[1,2,5]thiadi...) Show SMILES Cn1c2nsnc2c(=O)n(CCCC(O)=O)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048950 (4-(8-Mercapto-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetra...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048944 (4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...) Show SMILES Cn1c2nccnc2c(=O)n(CCCC(O)=O)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50048930 (4-(8-Bromo-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahyd...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description TNF-alpha production in PBMC by ELISA method				J Med Chem 39: 2-9 (1996) Article DOI: 10.1021/jm940845j BindingDB Entry DOI: 10.7270/Q29S1Q46
University of California Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%