Affinity Data by PubMed id=8893842

PubMed code 8893842

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50054439 ((S)-3-Amino-N-[3-((S)-1-{[2-(3,4-dichloro-phenyl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Compound was tested for the binding affinity and selectivity by competitive inhibition of radioligands on opoid kappa receptor in guinea pig brain me...				J Med Chem 39: 4478-82 (1996) Article DOI: 10.1021/jm960459x BindingDB Entry DOI: 10.7270/Q2N878WW
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50054440 ((R)-3-Amino-N-[3-((S)-1-{[2-(3,4-dichloro-phenyl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Compound was tested for the binding affinity and selectivity by competitive inhibition of radioligands on Opioid receptor kappa 1 in guinea pig brain...				J Med Chem 39: 4478-82 (1996) Article DOI: 10.1021/jm960459x BindingDB Entry DOI: 10.7270/Q2N878WW
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50054440 ((R)-3-Amino-N-[3-((S)-1-{[2-(3,4-dichloro-phenyl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Compound was tested for the binding affinity and selectivity by competitive inhibition of radioligands on opioid Mu receptor in guinea pig brain memb...				J Med Chem 39: 4478-82 (1996) Article DOI: 10.1021/jm960459x BindingDB Entry DOI: 10.7270/Q2N878WW
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50054439 ((S)-3-Amino-N-[3-((S)-1-{[2-(3,4-dichloro-phenyl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	462	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Compound was tested for the binding affinity and selectivity by competitive inhibition of radioligands on opioid Mu receptor in guinea pig brain memb...				J Med Chem 39: 4478-82 (1996) Article DOI: 10.1021/jm960459x BindingDB Entry DOI: 10.7270/Q2N878WW
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50054440 ((R)-3-Amino-N-[3-((S)-1-{[2-(3,4-dichloro-phenyl)-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	573	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Compound was tested for the binding affinity and selectivity by competitive inhibition of radioligands on opioid delta receptor in guinea pig brain m...				J Med Chem 39: 4478-82 (1996) Article DOI: 10.1021/jm960459x BindingDB Entry DOI: 10.7270/Q2N878WW
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50054439 ((S)-3-Amino-N-[3-((S)-1-{[2-(3,4-dichloro-phenyl)-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Compound was tested for the binding affinity and selectivity by competitive inhibition of radioligands on opioid delta receptor in guinea pig brain m...				J Med Chem 39: 4478-82 (1996) Article DOI: 10.1021/jm960459x BindingDB Entry DOI: 10.7270/Q2N878WW
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%