Affinity Data by PubMed id=8904845

PubMed code 8904845

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50292361 (8(S)-amino-2(R)-methyl-7-oxononanoic acid \| CHEMBL...) Show SMILES C[C@H](N)C(=O)CCCC[C@@H](C)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 aminopeptidase activity spectrophotometric analysis				J Nat Prod 59: 962-4 (1997) Article DOI: 10.1021/np9603986 BindingDB Entry DOI: 10.7270/Q2XP74ZR
Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50292361 (8(S)-amino-2(R)-methyl-7-oxononanoic acid \| CHEMBL...) Show SMILES C[C@H](N)C(=O)CCCC[C@@H](C)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase assessed as LTB4 production after 30 mins by ELISA				J Nat Prod 59: 962-4 (1997) Article DOI: 10.1021/np9603986 BindingDB Entry DOI: 10.7270/Q2XP74ZR
Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50292361 (8(S)-amino-2(R)-methyl-7-oxononanoic acid \| CHEMBL...) Show SMILES C[C@H](N)C(=O)CCCC[C@@H](C)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibition of rabbit lung ACE				J Nat Prod 59: 962-4 (1997) Article DOI: 10.1021/np9603986 BindingDB Entry DOI: 10.7270/Q2XP74ZR
Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%