Found 119 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055305
(CHEMBL423762 | Sodium; (1-biphenyl-2-ylmethyl-3-ca...)Show SMILES Cc1c(CC(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H24N2O4/c1-17-21(14-24(27)29)26-22(12-7-13-23(26)32-16-25(30)31)28(17)15-19-10-5-6-11-20(19)18-8-3-2-4-9-18/h2-13H,14-16H2,1H3,(H2,27,29)(H,30,31)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055305
(CHEMBL423762 | Sodium; (1-biphenyl-2-ylmethyl-3-ca...)Show SMILES Cc1c(CC(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H24N2O4/c1-17-21(14-24(27)29)26-22(12-7-13-23(26)32-16-25(30)31)28(17)15-19-10-5-6-11-20(19)18-8-3-2-4-9-18/h2-13H,14-16H2,1H3,(H2,27,29)(H,30,31)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055315
(CHEMBL359304 | [3-(1-Benzyl-3-carbamoylmethyl-2-et...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)c(C)cc2n1Cc1ccccc1 Show InChI InChI=1S/C23H29N2O5P/c1-3-20-19(14-23(24)26)18-13-22(30-10-7-11-31(27,28)29)16(2)12-21(18)25(20)15-17-8-5-4-6-9-17/h4-6,8-9,12-13H,3,7,10-11,14-15H2,1-2H3,(H2,24,26)(H2,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055355
(CHEMBL148601 | {3-[3-Carbamoylmethyl-1-(3-chloro-b...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1cccc(Cl)c1 Show InChI InChI=1S/C22H26ClN2O5P/c1-2-20-19(13-22(24)26)18-12-17(30-9-4-10-31(27,28)29)7-8-21(18)25(20)14-15-5-3-6-16(23)11-15/h3,5-8,11-12H,2,4,9-10,13-14H2,1H3,(H2,24,26)(H2,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055351
(4-(1-Benzyl-2-bromo-3-carbamoylmethyl-6-chloro-1H-...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2cc(Cl)c(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H20BrClN2O4/c22-21-15(10-19(24)26)14-9-18(29-8-4-7-20(27)28)16(23)11-17(14)25(21)12-13-5-2-1-3-6-13/h1-3,5-6,9,11H,4,7-8,10,12H2,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055334
(CHEMBL148479 | Sodium; [3-carbamoylmethyl-1-(3-chl...)Show SMILES Cc1c(CC(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1cccc(Cl)c1 Show InChI InChI=1S/C20H19ClN2O4/c1-12-15(9-18(22)24)20-16(6-3-7-17(20)27-11-19(25)26)23(12)10-13-4-2-5-14(21)8-13/h2-8H,9-11H2,1H3,(H2,22,24)(H,25,26)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055294
(CHEMBL423205 | [3-(1-Biphenyl-2-ylmethyl-3-carbamo...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H29N2O5P/c1-19-24(17-27(28)30)25-16-22(34-14-7-15-35(31,32)33)12-13-26(25)29(19)18-21-10-5-6-11-23(21)20-8-3-2-4-9-20/h2-6,8-13,16H,7,14-15,17-18H2,1H3,(H2,28,30)(H2,31,32,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055312
(4-(1-Benzyl-3-carbamoylmethyl-2-ethyl-6-methyl-1H-...)Show SMILES CCc1c(CC(N)=O)c2cc(SCCCC(O)=O)c(C)cc2n1Cc1ccccc1 Show InChI InChI=1S/C24H28N2O3S/c1-3-20-19(14-23(25)27)18-13-22(30-11-7-10-24(28)29)16(2)12-21(18)26(20)15-17-8-5-4-6-9-17/h4-6,8-9,12-13H,3,7,10-11,14-15H2,1-2H3,(H2,25,27)(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055299
(4-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(SCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O3S/c1-2-20-19(14-22(24)26)18-13-17(29-12-6-9-23(27)28)10-11-21(18)25(20)15-16-7-4-3-5-8-16/h3-5,7-8,10-11,13H,2,6,9,12,14-15H2,1H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H27N2O5P/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H2,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055298
((1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-4-ylo...)Show SMILES CCc1c(CC(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H22N2O4/c1-2-16-15(11-19(22)24)21-17(9-6-10-18(21)27-13-20(25)26)23(16)12-14-7-4-3-5-8-14/h3-10H,2,11-13H2,1H3,(H2,22,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055295
(4-(1-Benzyl-3-carbamoylmethyl-2-ethyl-6-isopropyl-...)Show SMILES CCc1c(CC(N)=O)c2cc(SCCCC(O)=O)c(cc2n1Cc1ccccc1)C(C)C Show InChI InChI=1S/C26H32N2O3S/c1-4-22-21(15-25(27)29)20-14-24(32-12-8-11-26(30)31)19(17(2)3)13-23(20)28(22)16-18-9-6-5-7-10-18/h5-7,9-10,13-14,17H,4,8,11-12,15-16H2,1-3H3,(H2,27,29)(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055293
(4-(1-Benzyl-3-carbamoylmethyl-2-ethyl-6-methyl-1H-...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCC(O)=O)c(C)cc2n1Cc1ccccc1 Show InChI InChI=1S/C24H28N2O4/c1-3-20-19(14-23(25)27)18-13-22(30-11-7-10-24(28)29)16(2)12-21(18)26(20)15-17-8-5-4-6-9-17/h4-6,8-9,12-13H,3,7,10-11,14-15H2,1-2H3,(H2,25,27)(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055292
(CHEMBL358049 | [3-(1-Benzyl-2-bromo-3-carbamoylmet...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2ccc(OCCCP(O)(O)=O)cc12 Show InChI InChI=1S/C20H22BrN2O5P/c21-20-17(12-19(22)24)16-11-15(28-9-4-10-29(25,26)27)7-8-18(16)23(20)13-14-5-2-1-3-6-14/h1-3,5-8,11H,4,9-10,12-13H2,(H2,22,24)(H2,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055289
(CHEMBL146229 | [3-Carbamoylmethyl-1-(3-chloro-benz...)Show SMILES CCc1c(CC(N)=O)c2c(OCC(O)=O)cccc2n1Cc1cccc(Cl)c1 Show InChI InChI=1S/C21H21ClN2O4/c1-2-16-15(10-19(23)25)21-17(7-4-8-18(21)28-12-20(26)27)24(16)11-13-5-3-6-14(22)9-13/h3-9H,2,10-12H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055303
(CHEMBL150154 | [3-(1-Benzyl-3-carbamoylmethyl-2-et...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(=O)OC)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C23H29N2O5P/c1-3-21-20(15-23(24)26)19-14-18(30-12-7-13-31(27,28)29-2)10-11-22(19)25(21)16-17-8-5-4-6-9-17/h4-6,8-11,14H,3,7,12-13,15-16H2,1-2H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055365
(CHEMBL149075 | [3-(1-Benzyl-3-carbamoylmethyl-2-et...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)c(cc2n1Cc1ccccc1)C(C)C Show InChI InChI=1S/C25H33N2O5P/c1-4-22-21(15-25(26)28)20-14-24(32-11-8-12-33(29,30)31)19(17(2)3)13-23(20)27(22)16-18-9-6-5-7-10-18/h5-7,9-10,13-14,17H,4,8,11-12,15-16H2,1-3H3,(H2,26,28)(H2,29,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055346
(CHEMBL148500 | Sodium; (1-benzyl-3-carbamoylmethyl...)Show SMILES Cc1c(CC(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C20H20N2O4/c1-13-15(10-18(21)23)20-16(8-5-9-17(20)26-12-19(24)25)22(13)11-14-6-3-2-4-7-14/h2-9H,10-12H2,1H3,(H2,21,23)(H,24,25)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055347
(4-(1-Benzyl-3-carbamoylmethyl-2-cyclopropyl-1H-ind...)Show SMILES NC(=O)Cc1c(C2CC2)n(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12 Show InChI InChI=1S/C24H26N2O4/c25-22(27)14-20-19-13-18(30-12-4-7-23(28)29)10-11-21(19)26(24(20)17-8-9-17)15-16-5-2-1-3-6-16/h1-3,5-6,10-11,13,17H,4,7-9,12,14-15H2,(H2,25,27)(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055316
(3-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCS(O)(=O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H26N2O5S/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055307
(4-(1-Benzyl-3-carbamoylmethyl-2,7-dimethyl-1H-indo...)Show SMILES Cc1c(CC(N)=O)c2cc(SCCCC(O)=O)cc(C)c2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O3S/c1-15-11-18(29-10-6-9-22(27)28)12-20-19(13-21(24)26)16(2)25(23(15)20)14-17-7-4-3-5-8-17/h3-5,7-8,11-12H,6,9-10,13-14H2,1-2H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055331
((1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yl...)Show InChI InChI=1S/C20H20N2O4/c1-13-15(10-18(21)23)20-16(8-5-9-17(20)26-12-19(24)25)22(13)11-14-6-3-2-4-7-14/h2-9H,10-12H2,1H3,(H2,21,23)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055334
(CHEMBL148479 | Sodium; [3-carbamoylmethyl-1-(3-chl...)Show SMILES Cc1c(CC(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1cccc(Cl)c1 Show InChI InChI=1S/C20H19ClN2O4/c1-12-15(9-18(22)24)20-16(6-3-7-17(20)27-11-19(25)26)23(12)10-13-4-2-5-14(21)8-13/h2-8H,9-11H2,1H3,(H2,22,24)(H,25,26)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055341
(CHEMBL149502 | [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-ME...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H25N2O5P/c1-15-18(13-21(22)24)19-12-17(28-10-5-11-29(25,26)27)8-9-20(19)23(15)14-16-6-3-2-4-7-16/h2-4,6-9,12H,5,10-11,13-14H2,1H3,(H2,22,24)(H2,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055306
(CHEMBL355966 | Sodium salt of [3-(1-Benzyl-3-carba...)Show SMILES CCc1c(CC(N)=O)c2cc(SCCCP([O-])([O-])=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H27N2O4PS/c1-2-20-19(14-22(23)25)18-13-17(30-12-6-11-29(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H2,26,27,28)/p-2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055313
(3-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(SCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O3S/c1-2-19-18(13-21(23)25)17-12-16(28-11-10-22(26)27)8-9-20(17)24(19)14-15-6-4-3-5-7-15/h3-9,12H,2,10-11,13-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055321
(4-(1-Benzyl-2-bromo-3-carbamoylmethyl-1H-indol-5-y...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H21BrN2O4/c22-21-17(12-19(23)25)16-11-15(28-10-4-7-20(26)27)8-9-18(16)24(21)13-14-5-2-1-3-6-14/h1-3,5-6,8-9,11H,4,7,10,12-13H2,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055350
(CHEMBL356306 | [3-(1-Benzyl-3-carbamoylmethyl-2-cy...)Show SMILES NC(=O)Cc1c(C2CC2)n(Cc2ccccc2)c2ccc(OCCCP(O)(O)=O)cc12 Show InChI InChI=1S/C23H27N2O5P/c24-22(26)14-20-19-13-18(30-11-4-12-31(27,28)29)9-10-21(19)25(23(20)17-7-8-17)15-16-5-2-1-3-6-16/h1-3,5-6,9-10,13,17H,4,7-8,11-12,14-15H2,(H2,24,26)(H2,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055311
(4-(1-Benzyl-3-carbamoylmethyl-2,7-dimethyl-1H-indo...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCC(O)=O)cc(C)c2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O4/c1-15-11-18(29-10-6-9-22(27)28)12-20-19(13-21(24)26)16(2)25(23(15)20)14-17-7-4-3-5-8-17/h3-5,7-8,11-12H,6,9-10,13-14H2,1-2H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055314
(4-(1-Benzyl-3-carbamoylmethyl-2-chloro-1H-indol-5-...)Show SMILES NC(=O)Cc1c(Cl)n(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H21ClN2O4/c22-21-17(12-19(23)25)16-11-15(28-10-4-7-20(26)27)8-9-18(16)24(21)13-14-5-2-1-3-6-14/h1-3,5-6,8-9,11H,4,7,10,12-13H2,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055356
(2-(1-Benzyl-2-bromo-6-chloro-5-hydroxy-1H-indol-3-...)Show InChI InChI=1S/C17H14BrClN2O2/c18-17-12(7-16(20)23)11-6-15(22)13(19)8-14(11)21(17)9-10-4-2-1-3-5-10/h1-6,8,22H,7,9H2,(H2,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055353
(4-(1-Benzyl-3-carbamoylmethyl-2-methylsulfanyl-1H-...)Show SMILES CSc1c(CC(N)=O)c2cc(OCCCC(N)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H25N3O3S/c1-29-22-18(13-21(24)27)17-12-16(28-11-5-8-20(23)26)9-10-19(17)25(22)14-15-6-3-2-4-7-15/h2-4,6-7,9-10,12H,5,8,11,13-14H2,1H3,(H2,23,26)(H2,24,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055360
(2-(1-Benzyl-2-cyclopropyl-5-hydroxy-1H-indol-3-yl)...)Show InChI InChI=1S/C20H20N2O2/c21-19(24)11-17-16-10-15(23)8-9-18(16)22(20(17)14-6-7-14)12-13-4-2-1-3-5-13/h1-5,8-10,14,23H,6-7,11-12H2,(H2,21,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055296
(2-(1-Benzyl-2-ethyl-4-hydrazinocarbonylmethoxy-1H-...)Show SMILES CCc1c(CC(N)=O)c2c(OCC(=O)NN)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H24N4O3/c1-2-16-15(11-19(22)26)21-17(25(16)12-14-7-4-3-5-8-14)9-6-10-18(21)28-13-20(27)24-23/h3-10H,2,11-13,23H2,1H3,(H2,22,26)(H,24,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055298
((1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-4-ylo...)Show SMILES CCc1c(CC(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H22N2O4/c1-2-16-15(11-19(22)24)21-17(9-6-10-18(21)27-13-20(25)26)23(16)12-14-7-4-3-5-8-14/h3-10H,2,11-13H2,1H3,(H2,22,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055320
(2-(4-Allyl-1-benzyl-2-ethyl-5-hydroxy-1H-indol-3-y...)Show InChI InChI=1S/C22H24N2O2/c1-3-8-16-20(25)12-11-19-22(16)17(13-21(23)26)18(4-2)24(19)14-15-9-6-5-7-10-15/h3,5-7,9-12,25H,1,4,8,13-14H2,2H3,(H2,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055302
(2-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCc3ccccc3C(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C26H24N2O4/c1-17-22(14-25(27)29)23-13-20(32-16-19-9-5-6-10-21(19)26(30)31)11-12-24(23)28(17)15-18-7-3-2-4-8-18/h2-13H,14-16H2,1H3,(H2,27,29)(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 147 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055331
((1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yl...)Show InChI InChI=1S/C20H20N2O4/c1-13-15(10-18(21)23)20-16(8-5-9-17(20)26-12-19(24)25)22(13)11-14-6-3-2-4-7-14/h2-9H,10-12H2,1H3,(H2,21,23)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055291
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-18(13-21(23)25)19-12-17(28-11-5-8-22(26)27)9-10-20(19)24(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12H,5,8,11,13-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 152 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055340
(2-(1-Benzyl-4-carbamoylmethoxy-2-ethyl-1H-indol-3-...)Show SMILES CCc1c(CC(N)=O)c2c(OCC(N)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H23N3O3/c1-2-16-15(11-19(22)25)21-17(9-6-10-18(21)27-13-20(23)26)24(16)12-14-7-4-3-5-8-14/h3-10H,2,11-13H2,1H3,(H2,22,25)(H2,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055286
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(CCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O3/c1-15-18(13-21(23)25)19-12-16(8-5-9-22(26)27)10-11-20(19)24(15)14-17-6-3-2-4-7-17/h2-4,6-7,10-12H,5,8-9,13-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055297
(4-(1-Benzyl-3-carbamoylmethyl-2-methylsulfanyl-1H-...)Show SMILES CSc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4S/c1-29-22-18(13-20(23)25)17-12-16(28-11-5-8-21(26)27)9-10-19(17)24(22)14-15-6-3-2-4-7-15/h2-4,6-7,9-10,12H,5,8,11,13-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 162 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055288
(CHEMBL358567 | Sodium salt of [3-(1-Benzyl-2-bromo...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2ccc(OCCCP([O-])([O-])=O)cc12 Show InChI InChI=1S/C20H22BrN2O5P/c21-20-17(12-19(22)24)16-11-15(28-9-4-10-29(25,26)27)7-8-18(16)23(20)13-14-5-2-1-3-6-14/h1-3,5-8,11H,4,9-10,12-13H2,(H2,22,24)(H2,25,26,27)/p-2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 165 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055332
(4-(1-Benzyl-3-carbamoylmethyl-1H-indol-5-yloxy)-bu...)Show SMILES NC(=O)Cc1cn(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H22N2O4/c22-20(24)11-16-14-23(13-15-5-2-1-3-6-15)19-9-8-17(12-18(16)19)27-10-4-7-21(25)26/h1-3,5-6,8-9,12,14H,4,7,10-11,13H2,(H2,22,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055337
(4-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O4/c1-2-20-19(14-22(24)26)18-13-17(29-12-6-9-23(27)28)10-11-21(18)25(20)15-16-7-4-3-5-8-16/h3-5,7-8,10-11,13H,2,6,9,12,14-15H2,1H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 189 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055362
(3-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCS(O)(=O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H24N2O5S/c1-15-18(13-21(22)24)19-12-17(28-10-5-11-29(25,26)27)8-9-20(19)23(15)14-16-6-3-2-4-7-16/h2-4,6-9,12H,5,10-11,13-14H2,1H3,(H2,22,24)(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 195 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055342
(CHEMBL148924 | [3-(1-Benzyl-3-carbamoylmethyl-1H-i...)Show SMILES NC(=O)Cc1cn(Cc2ccccc2)c2ccc(OCCCP(O)(O)=O)cc12 Show InChI InChI=1S/C20H23N2O5P/c21-20(23)11-16-14-22(13-15-5-2-1-3-6-15)19-8-7-17(12-18(16)19)27-9-4-10-28(24,25)26/h1-3,5-8,12,14H,4,9-11,13H2,(H2,21,23)(H2,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 203 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055349
(CHEMBL356887 | [3-(1-Benzyl-3-carbamoylmethyl-2-et...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(=O)(OC)OC)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C24H31N2O5P/c1-4-22-21(16-24(25)27)20-15-19(31-13-8-14-32(28,29-2)30-3)11-12-23(20)26(22)17-18-9-6-5-7-10-18/h5-7,9-12,15H,4,8,13-14,16-17H2,1-3H3,(H2,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 266 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055363
(5-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-6-...)Show SMILES CCOC(=O)CCCCOc1ccc2c(CC(N)=O)c(C)n(Cc3ccccc3)c2c1 Show InChI InChI=1S/C25H30N2O4/c1-3-30-25(29)11-7-8-14-31-20-12-13-21-22(16-24(26)28)18(2)27(23(21)15-20)17-19-9-5-4-6-10-19/h4-6,9-10,12-13,15H,3,7-8,11,14,16-17H2,1-2H3,(H2,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 306 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055290
((1-Benzyl-3-carbamoylmethyl-1H-indol-4-yloxy)-acet...)Show InChI InChI=1S/C19H18N2O4/c20-17(22)9-14-11-21(10-13-5-2-1-3-6-13)15-7-4-8-16(19(14)15)25-12-18(23)24/h1-8,11H,9-10,12H2,(H2,20,22)(H,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 321 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055329
(2-(1-Benzyl-2-ethyl-5-hydroxy-1H-indol-3-yl)-aceta...)Show InChI InChI=1S/C19H20N2O2/c1-2-17-16(11-19(20)23)15-10-14(22)8-9-18(15)21(17)12-13-6-4-3-5-7-13/h3-10,22H,2,11-12H2,1H3,(H2,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 342 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055328
(2-(1-Benzyl-4-carbamoylmethoxy-2-methyl-1H-indol-3...)Show InChI InChI=1S/C20H21N3O3/c1-13-15(10-18(21)24)20-16(8-5-9-17(20)26-12-19(22)25)23(13)11-14-6-3-2-4-7-14/h2-9H,10-12H2,1H3,(H2,21,24)(H2,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055318
(2-(1-Benzyl-5-hydroxy-2-methylsulfanyl-1H-indol-3-...)Show InChI InChI=1S/C18H18N2O2S/c1-23-18-15(10-17(19)22)14-9-13(21)7-8-16(14)20(18)11-12-5-3-2-4-6-12/h2-9,21H,10-11H2,1H3,(H2,19,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 379 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055287
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)Show SMILES Cc1c(CC(N)=O)c2c(OCCCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-17(13-20(23)25)22-18(24(15)14-16-7-3-2-4-8-16)9-5-10-19(22)28-12-6-11-21(26)27/h2-5,7-10H,6,11-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 399 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055343
(2-(1-Benzyl-4-hydrazinocarbonylmethoxy-2-methyl-1H...)Show SMILES Cc1c(CC(N)=O)c2c(OCC(=O)NN)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C20H22N4O3/c1-13-15(10-18(21)25)20-16(24(13)11-14-6-3-2-4-7-14)8-5-9-17(20)27-12-19(26)23-22/h2-9H,10-12,22H2,1H3,(H2,21,25)(H,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 422 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055327
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-6-...)Show SMILES CCOC(=O)CCCOc1ccc2c(CC(N)=O)c(C)n(Cc3ccccc3)c2c1 Show InChI InChI=1S/C24H28N2O4/c1-3-29-24(28)10-7-13-30-19-11-12-20-21(15-23(25)27)17(2)26(22(20)14-19)16-18-8-5-4-6-9-18/h4-6,8-9,11-12,14H,3,7,10,13,15-16H2,1-2H3,(H2,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055335
(CHEMBL146739 | Sodium salt of [3-(1-Benzyl-3-hydra...)Show SMILES Cc1c(CC(=O)NN)c2cc(OCCCP([O-])([O-])=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H26N3O5P/c1-15-18(13-21(25)23-22)19-12-17(29-10-5-11-30(26,27)28)8-9-20(19)24(15)14-16-6-3-2-4-7-16/h2-4,6-9,12H,5,10-11,13-14,22H2,1H3,(H,23,25)(H2,26,27,28)/p-2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 462 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055364
(3-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H22N2O4/c1-14-17(12-20(22)24)18-11-16(27-10-9-21(25)26)7-8-19(18)23(14)13-15-5-3-2-4-6-15/h2-8,11H,9-10,12-13H2,1H3,(H2,22,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 527 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055358
(2-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(OCc3ccccc3C(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C27H26N2O4/c1-2-24-23(15-26(28)30)22-14-20(33-17-19-10-6-7-11-21(19)27(31)32)12-13-25(22)29(24)16-18-8-4-3-5-9-18/h3-14H,2,15-17H2,1H3,(H2,28,30)(H,31,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 555 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055287
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)Show SMILES Cc1c(CC(N)=O)c2c(OCCCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-17(13-20(23)25)22-18(24(15)14-16-7-3-2-4-8-16)9-5-10-19(22)28-12-6-11-21(26)27/h2-5,7-10H,6,11-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, major isoenzyme
(Sus scrofa (pig)) | BDBM50055287
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)Show SMILES Cc1c(CC(N)=O)c2c(OCCCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-17(13-20(23)25)22-18(24(15)14-16-7-3-2-4-8-16)9-5-10-19(22)28-12-6-11-21(26)27/h2-5,7-10H,6,11-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibitory activity against porcine pancreatic PLA2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055348
(CHEMBL149330 | Sodium salt of [3-(6-Allyl-1-benzyl...)Show SMILES CCc1c(CC(N)=O)c2c(CC=C)c(OCCCP([O-])([O-])=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C25H31N2O5P/c1-3-9-19-23(32-14-8-15-33(29,30)31)13-12-22-25(19)20(16-24(26)28)21(4-2)27(22)17-18-10-6-5-7-11-18/h3,5-7,10-13H,1,4,8-9,14-17H2,2H3,(H2,26,28)(H2,29,30,31)/p-2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 612 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055339
((1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-4-yl)...)Show InChI InChI=1S/C20H21N3O3/c1-2-16-14(11-18(21)24)19-15(22-20(25)26)9-6-10-17(19)23(16)12-13-7-4-3-5-8-13/h3-10,22H,2,11-12H2,1H3,(H2,21,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 619 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055344
(4-(3-Carbamoylmethyl-1-cyclohexylmethyl-2-methyl-1...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1CC1CCCCC1 Show InChI InChI=1S/C22H30N2O4/c1-15-18(13-21(23)25)19-12-17(28-11-5-8-22(26)27)9-10-20(19)24(15)14-16-6-3-2-4-7-16/h9-10,12,16H,2-8,11,13-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 654 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055352
(4-(3-Carbamoylmethyl-1-decyl-2-methyl-1H-indol-5-y...)Show SMILES CCCCCCCCCCn1c(C)c(CC(N)=O)c2cc(OCCCC(O)=O)ccc12 Show InChI InChI=1S/C25H38N2O4/c1-3-4-5-6-7-8-9-10-15-27-19(2)21(18-24(26)28)22-17-20(13-14-23(22)27)31-16-11-12-25(29)30/h13-14,17H,3-12,15-16,18H2,1-2H3,(H2,26,28)(H,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 683 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055308
(4-(1-Benzyl-3-hydrazinocarbonylmethyl-2-methyl-1H-...)Show SMILES Cc1c(CC(=O)NN)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H25N3O4/c1-15-18(13-21(26)24-23)19-12-17(29-11-5-8-22(27)28)9-10-20(19)25(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12H,5,8,11,13-14,23H2,1H3,(H,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055336
(2-(1-Benzyl-5-hydroxy-2-methyl-1H-indol-3-yl)-acet...)Show InChI InChI=1S/C18H18N2O2/c1-12-15(10-18(19)22)16-9-14(21)7-8-17(16)20(12)11-13-5-3-2-4-6-13/h2-9,21H,10-11H2,1H3,(H2,19,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055284
(5-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O4/c1-16-19(14-22(24)26)20-13-18(29-12-6-5-9-23(27)28)10-11-21(20)25(16)15-17-7-3-2-4-8-17/h2-4,7-8,10-11,13H,5-6,9,12,14-15H2,1H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055334
(CHEMBL148479 | Sodium; [3-carbamoylmethyl-1-(3-chl...)Show SMILES Cc1c(CC(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1cccc(Cl)c1 Show InChI InChI=1S/C20H19ClN2O4/c1-12-15(9-18(22)24)20-16(6-3-7-17(20)27-11-19(25)26)23(12)10-13-4-2-5-14(21)8-13/h2-8H,9-11H2,1H3,(H2,22,24)(H,25,26)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055317
(4-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCOC(=O)CCCOc1ccc2n(Cc3ccccc3)c(CC)c(CC(N)=O)c2c1 Show InChI InChI=1S/C25H30N2O4/c1-3-22-21(16-24(26)28)20-15-19(31-14-8-11-25(29)30-4-2)12-13-23(20)27(22)17-18-9-6-5-7-10-18/h5-7,9-10,12-13,15H,3-4,8,11,14,16-17H2,1-2H3,(H2,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055322
(2-[1-Benzyl-6-(3-hydrazinocarbonyl-propoxy)-2-meth...)Show SMILES Cc1c(CC(N)=O)c2ccc(OCCCC(=O)NN)cc2n1Cc1ccccc1 Show InChI InChI=1S/C22H26N4O3/c1-15-19(13-21(23)27)18-10-9-17(29-11-5-8-22(28)25-24)12-20(18)26(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12H,5,8,11,13-14,24H2,1H3,(H2,23,27)(H,25,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055309
((1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yl...)Show SMILES Cc1c(CC(N)=O)c2c(OCP(O)(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C19H21N2O5P/c1-13-15(10-18(20)22)19-16(21(13)11-14-6-3-2-4-7-14)8-5-9-17(19)26-12-27(23,24)25/h2-9H,10-12H2,1H3,(H2,20,22)(H2,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055351
(4-(1-Benzyl-2-bromo-3-carbamoylmethyl-6-chloro-1H-...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2cc(Cl)c(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H20BrClN2O4/c22-21-15(10-19(24)26)14-9-18(29-8-4-7-20(27)28)16(23)11-17(14)25(21)12-13-5-2-1-3-6-13/h1-3,5-6,9,11H,4,7-8,10,12H2,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055361
((1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yl...)Show SMILES COC(=O)COc1cccc2n(Cc3ccccc3)c(C)c(CC(N)=O)c12 Show InChI InChI=1S/C21H22N2O4/c1-14-16(11-19(22)24)21-17(23(14)12-15-7-4-3-5-8-15)9-6-10-18(21)27-13-20(25)26-2/h3-10H,11-13H2,1-2H3,(H2,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055331
((1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yl...)Show InChI InChI=1S/C20H20N2O4/c1-13-15(10-18(21)23)20-16(8-5-9-17(20)26-12-19(24)25)22(13)11-14-6-3-2-4-7-14/h2-9H,10-12H2,1H3,(H2,21,23)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055301
((1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-yl...)Show InChI InChI=1S/C20H20N2O4/c1-13-16(10-19(21)23)17-9-15(26-12-20(24)25)7-8-18(17)22(13)11-14-5-3-2-4-6-14/h2-9H,10-12H2,1H3,(H2,21,23)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055298
((1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-4-ylo...)Show SMILES CCc1c(CC(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H22N2O4/c1-2-16-15(11-19(22)24)21-17(9-6-10-18(21)27-13-20(25)26)23(16)12-14-7-4-3-5-8-14/h3-10H,2,11-13H2,1H3,(H2,22,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055338
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(NCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H25N3O3/c1-15-18(13-21(23)26)19-12-17(24-11-5-8-22(27)28)9-10-20(19)25(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12,24H,5,8,11,13-14H2,1H3,(H2,23,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055357
(3-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCc3cccc(c3)C(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C26H24N2O4/c1-17-22(14-25(27)29)23-13-21(32-16-19-8-5-9-20(12-19)26(30)31)10-11-24(23)28(17)15-18-6-3-2-4-7-18/h2-13H,14-16H2,1H3,(H2,27,29)(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055292
(CHEMBL358049 | [3-(1-Benzyl-2-bromo-3-carbamoylmet...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2ccc(OCCCP(O)(O)=O)cc12 Show InChI InChI=1S/C20H22BrN2O5P/c21-20-17(12-19(22)24)16-11-15(28-9-4-10-29(25,26)27)7-8-18(16)23(20)13-14-5-2-1-3-6-14/h1-3,5-8,11H,4,9-10,12-13H2,(H2,22,24)(H2,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055324
(2-{1-Benzyl-5-[3-(2,3-dihydro-1H-tetrazol-5-yl)-pr...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCC3=NNNN3)ccc2n1Cc1ccccc1 |t:14| Show InChI InChI=1S/C22H26N6O2/c1-15-18(13-21(23)29)19-12-17(30-11-5-8-22-24-26-27-25-22)9-10-20(19)28(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12,26-27H,5,8,11,13-14H2,1H3,(H2,23,29)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055351
(4-(1-Benzyl-2-bromo-3-carbamoylmethyl-6-chloro-1H-...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2cc(Cl)c(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H20BrClN2O4/c22-21-15(10-19(24)26)14-9-18(29-8-4-7-20(27)28)16(23)11-17(14)25(21)12-13-5-2-1-3-6-13/h1-3,5-6,9,11H,4,7-8,10,12H2,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055325
(3-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(NCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H23N3O3/c1-14-17(12-20(22)25)18-11-16(23-10-9-21(26)27)7-8-19(18)24(14)13-15-5-3-2-4-6-15/h2-8,11,23H,9-10,12-13H2,1H3,(H2,22,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055304
(2-(1-Benzyl-6-hydroxy-2-methyl-1H-indol-3-yl)-acet...)Show InChI InChI=1S/C18H18N2O2/c1-12-16(10-18(19)22)15-8-7-14(21)9-17(15)20(12)11-13-5-3-2-4-6-13/h2-9,21H,10-11H2,1H3,(H2,19,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, major isoenzyme
(Sus scrofa (pig)) | BDBM50055287
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)Show SMILES Cc1c(CC(N)=O)c2c(OCCCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-17(13-20(23)25)22-18(24(15)14-16-7-3-2-4-8-16)9-5-10-19(22)28-12-6-11-21(26)27/h2-5,7-10H,6,11-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibitory activity against human pancreatic PLA2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055287
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)Show SMILES Cc1c(CC(N)=O)c2c(OCCCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-17(13-20(23)25)22-18(24(15)14-16-7-3-2-4-8-16)9-5-10-19(22)28-12-6-11-21(26)27/h2-5,7-10H,6,11-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055300
(2-(1-Benzyl-5-hydroxy-1H-indol-3-yl)-acetamide | C...)Show InChI InChI=1S/C17H16N2O2/c18-17(21)8-13-11-19(10-12-4-2-1-3-5-12)16-7-6-14(20)9-15(13)16/h1-7,9,11,20H,8,10H2,(H2,18,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055310
(CHEMBL343906 | Sodium salt of (1-Benzyl-3-carbamoy...)Show SMILES NC(=O)Cc1cn(Cc2ccccc2)c2ccc(OCP([O-])([O-])=O)cc12 Show InChI InChI=1S/C18H19N2O5P/c19-18(21)8-14-11-20(10-13-4-2-1-3-5-13)17-7-6-15(9-16(14)17)25-12-26(22,23)24/h1-7,9,11H,8,10,12H2,(H2,19,21)(H2,22,23,24)/p-2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055305
(CHEMBL423762 | Sodium; (1-biphenyl-2-ylmethyl-3-ca...)Show SMILES Cc1c(CC(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H24N2O4/c1-17-21(14-24(27)29)26-22(12-7-13-23(26)32-16-25(30)31)28(17)15-19-10-5-6-11-20(19)18-8-3-2-4-9-18/h2-13H,14-16H2,1H3,(H2,27,29)(H,30,31)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055309
((1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yl...)Show SMILES Cc1c(CC(N)=O)c2c(OCP(O)(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C19H21N2O5P/c1-13-15(10-18(20)22)19-16(21(13)11-14-6-3-2-4-7-14)8-5-9-17(19)26-12-27(23,24)25/h2-9H,10-12H2,1H3,(H2,20,22)(H2,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055316
(3-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCS(O)(=O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H26N2O5S/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055354
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-6-...)Show SMILES Cc1c(CC(N)=O)c2ccc(OCCCC(N)=O)cc2n1Cc1ccccc1 Show InChI InChI=1S/C22H25N3O3/c1-15-19(13-22(24)27)18-10-9-17(28-11-5-8-21(23)26)12-20(18)25(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12H,5,8,11,13-14H2,1H3,(H2,23,26)(H2,24,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055345
(2-[1-(3-Chloro-benzyl)-4-hydroxy-2-methyl-1H-indol...)Show InChI InChI=1S/C18H17ClN2O2/c1-11-14(9-17(20)23)18-15(6-3-7-16(18)22)21(11)10-12-4-2-5-13(19)8-12/h2-8,22H,9-10H2,1H3,(H2,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055319
(CHEMBL357931 | [3-(1-Benzyl-3-carbamoylmethyl-2-pr...)Show SMILES CCCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C23H29N2O5P/c1-2-7-21-20(15-23(24)26)19-14-18(30-12-6-13-31(27,28)29)10-11-22(19)25(21)16-17-8-4-3-5-9-17/h3-5,8-11,14H,2,6-7,12-13,15-16H2,1H3,(H2,24,26)(H2,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055292
(CHEMBL358049 | [3-(1-Benzyl-2-bromo-3-carbamoylmet...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2ccc(OCCCP(O)(O)=O)cc12 Show InChI InChI=1S/C20H22BrN2O5P/c21-20-17(12-19(22)24)16-11-15(28-9-4-10-29(25,26)27)7-8-18(16)23(20)13-14-5-2-1-3-6-14/h1-3,5-8,11H,4,9-10,12-13H2,(H2,22,24)(H2,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50408005
(CHEMBL2112027)Show SMILES Cc1c(CCC(N)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O4/c1-16-19(10-12-22(24)26)20-14-18(29-13-5-8-23(27)28)9-11-21(20)25(16)15-17-6-3-2-4-7-17/h2-4,6-7,9,11,14H,5,8,10,12-13,15H2,1H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055302
(2-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCc3ccccc3C(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C26H24N2O4/c1-17-22(14-25(27)29)23-13-20(32-16-19-9-5-6-10-21(19)26(30)31)11-12-24(23)28(17)15-18-7-3-2-4-8-18/h2-13H,14-16H2,1H3,(H2,27,29)(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055294
(CHEMBL423205 | [3-(1-Biphenyl-2-ylmethyl-3-carbamo...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H29N2O5P/c1-19-24(17-27(28)30)25-16-22(34-14-7-15-35(31,32)33)12-13-26(25)29(19)18-21-10-5-6-11-23(21)20-8-3-2-4-9-20/h2-6,8-13,16H,7,14-15,17-18H2,1H3,(H2,28,30)(H2,31,32,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055326
(5-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-6-...)Show SMILES Cc1c(CC(N)=O)c2ccc(OCCCCC(O)=O)cc2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O4/c1-16-20(14-22(24)26)19-11-10-18(29-12-6-5-9-23(27)28)13-21(19)25(16)15-17-7-3-2-4-8-17/h2-4,7-8,10-11,13H,5-6,9,12,14-15H2,1H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055330
(2-(1-Benzyl-4-hydroxy-2-methyl-1H-indol-3-yl)-acet...)Show InChI InChI=1S/C18H18N2O2/c1-12-14(10-17(19)22)18-15(8-5-9-16(18)21)20(12)11-13-6-3-2-4-7-13/h2-9,21H,10-11H2,1H3,(H2,19,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055333
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-6-...)Show SMILES Cc1c(CC(N)=O)c2ccc(OCCCC(O)=O)cc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-19(13-21(23)25)18-10-9-17(28-11-5-8-22(26)27)12-20(18)24(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12H,5,8,11,13-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055337
(4-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O4/c1-2-20-19(14-22(24)26)18-13-17(29-12-6-9-23(27)28)10-11-21(18)25(20)15-16-7-4-3-5-8-16/h3-5,7-8,10-11,13H,2,6,9,12,14-15H2,1H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055321
(4-(1-Benzyl-2-bromo-3-carbamoylmethyl-1H-indol-5-y...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H21BrN2O4/c22-21-17(12-19(23)25)16-11-15(28-10-4-7-20(26)27)8-9-18(16)24(21)13-14-5-2-1-3-6-14/h1-3,5-6,8-9,11H,4,7,10,12-13H2,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055321
(4-(1-Benzyl-2-bromo-3-carbamoylmethyl-1H-indol-5-y...)Show SMILES NC(=O)Cc1c(Br)n(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H21BrN2O4/c22-21-17(12-19(23)25)16-11-15(28-10-4-7-20(26)27)8-9-18(16)24(21)13-14-5-2-1-3-6-14/h1-3,5-6,8-9,11H,4,7,10,12-13H2,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50408004
(CHEMBL2112028)Show SMILES CCc1c(C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1cccc(Cl)c1 Show InChI InChI=1S/C20H19ClN2O4/c1-2-14-19(20(22)26)18-15(7-4-8-16(18)27-11-17(24)25)23(14)10-12-5-3-6-13(21)9-12/h3-9H,2,10-11H2,1H3,(H2,22,26)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055302
(2-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCc3ccccc3C(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C26H24N2O4/c1-17-22(14-25(27)29)23-13-20(32-16-19-9-5-6-10-21(19)26(30)31)11-12-24(23)28(17)15-18-7-3-2-4-8-18/h2-13H,14-16H2,1H3,(H2,27,29)(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055291
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-18(13-21(23)25)19-12-17(28-11-5-8-22(26)27)9-10-20(19)24(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12H,5,8,11,13-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055359
(4-(1-Benzyl-3-carboxymethyl-2-methyl-1H-indol-5-yl...)Show SMILES Cc1c(CC(O)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H23NO5/c1-15-18(13-22(26)27)19-12-17(28-11-5-8-21(24)25)9-10-20(19)23(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12H,5,8,11,13-14H2,1H3,(H,24,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055341
(CHEMBL149502 | [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-ME...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H25N2O5P/c1-15-18(13-21(22)24)19-12-17(28-10-5-11-29(25,26)27)8-9-20(19)23(15)14-16-6-3-2-4-7-16/h2-4,6-9,12H,5,10-11,13-14H2,1H3,(H2,22,24)(H2,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055323
(2-(1-Benzyl-5-hydroxy-2-propyl-1H-indol-3-yl)-acet...)Show InChI InChI=1S/C20H22N2O2/c1-2-6-18-17(12-20(21)24)16-11-15(23)9-10-19(16)22(18)13-14-7-4-3-5-8-14/h3-5,7-11,23H,2,6,12-13H2,1H3,(H2,21,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H27N2O5P/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H2,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 3.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against porcine pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055294
(CHEMBL423205 | [3-(1-Biphenyl-2-ylmethyl-3-carbamo...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H29N2O5P/c1-19-24(17-27(28)30)25-16-22(34-14-7-15-35(31,32)33)12-13-26(25)29(19)18-21-10-5-6-11-23(21)20-8-3-2-4-9-20/h2-6,8-13,16H,7,14-15,17-18H2,1H3,(H2,28,30)(H2,31,32,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055341
(CHEMBL149502 | [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-ME...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H25N2O5P/c1-15-18(13-21(22)24)19-12-17(28-10-5-11-29(25,26)27)8-9-20(19)23(15)14-16-6-3-2-4-7-16/h2-4,6-9,12H,5,10-11,13-14H2,1H3,(H2,22,24)(H2,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055291
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N2O4/c1-15-18(13-21(23)25)19-12-17(28-11-5-8-22(26)27)9-10-20(19)24(15)14-16-6-3-2-4-7-16/h2-4,6-7,9-10,12H,5,8,11,13-14H2,1H3,(H2,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055309
((1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yl...)Show SMILES Cc1c(CC(N)=O)c2c(OCP(O)(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C19H21N2O5P/c1-13-15(10-18(20)22)19-16(21(13)11-14-6-3-2-4-7-14)8-5-9-17(19)26-12-27(23,24)25/h2-9H,10-12H2,1H3,(H2,20,22)(H2,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H27N2O5P/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H2,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 9.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055337
(4-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C23H26N2O4/c1-2-20-19(14-22(24)26)18-13-17(29-12-6-9-23(27)28)10-11-21(18)25(20)15-16-7-4-3-5-8-16/h3-5,7-8,10-11,13H,2,6,9,12,14-15H2,1H3,(H2,24,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055285
(3-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-...)Show SMILES Cc1c(CC(N)=O)c2cc(Oc3cccc(c3)C(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C25H22N2O4/c1-16-21(14-24(26)28)22-13-20(31-19-9-5-8-18(12-19)25(29)30)10-11-23(22)27(16)15-17-6-3-2-4-7-17/h2-13H,14-15H2,1H3,(H2,26,28)(H,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
Phospholipase A2, membrane associated
(Homo sapiens (Human)) | BDBM50055316
(3-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...)Show SMILES CCc1c(CC(N)=O)c2cc(OCCCS(O)(=O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C22H26N2O5S/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human pancreatic Phospholipase A2 |
J Med Chem 39: 5137-58 (1997)
Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0 |
More data for this
Ligand-Target Pair | |
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