Affinity Data by PubMed id=9224565

Found 1 hit of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50099331 (4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...) Show SMILES Fc1ccc(cc1)-c1ncn(C2CCNCC2)c1-c1ccncc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	12	n/a	n/a	n/a	7.6	n/a
Vertex Pharmaceuticals					Assay Description Activation of p38 kinase assay was measured by fluorescence emission using a Perkin-Elmer LS 50B fluorimeter.				Chem Biol 4: 423-31 (1997) Article DOI: 10.1016/s1074-5521(97)90194-0 BindingDB Entry DOI: 10.7270/Q2S75DQF
Vertex Pharmaceuticals					More data for this Ligand-Target Pair				3D Structure (docked)

* indicates data uncertainty>20%