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PubMed code 9240351

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50027536
PNG
((phosphonoformate)Trisodium phosphonoformate | Ant...)
Show SMILES [O-]C(=O)P([O-])([O-])=O
Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
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Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.03E+3n/an/an/an/an/an/a



Life Science Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV-1 reverse transcriptase


J Med Chem 40: 2363-73 (1997)


Article DOI: 10.1021/jm9607921
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50059195
PNG
(6-(3,5-Dimethyl-phenylsulfanyl)-5-isopropyl-1-prop...)
Show SMILES CCCOn1c(Sc2cc(C)cc(C)c2)c(C(C)C)c(=O)[nH]c1=O
Show InChI InChI=1S/C18H24N2O3S/c1-6-7-23-20-17(15(11(2)3)16(21)19-18(20)22)24-14-9-12(4)8-13(5)10-14/h8-11H,6-7H2,1-5H3,(H,19,21,22)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.23E+4n/an/an/an/an/an/a



Life Science Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV-1 recombinant reverse transcriptase


J Med Chem 40: 2363-73 (1997)


Article DOI: 10.1021/jm9607921
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50027536
PNG
((phosphonoformate)Trisodium phosphonoformate | Ant...)
Show SMILES [O-]C(=O)P([O-])([O-])=O
Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.76E+4n/an/an/an/an/an/a



Life Science Research Center

Curated by ChEMBL


Assay Description
Inhibitory effect of the compound on Molony Murine Leukemia virus (mo-MuLv) Recombiannt Reverse transcriptase


J Med Chem 40: 2363-73 (1997)


Article DOI: 10.1021/jm9607921
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50059195
PNG
(6-(3,5-Dimethyl-phenylsulfanyl)-5-isopropyl-1-prop...)
Show SMILES CCCOn1c(Sc2cc(C)cc(C)c2)c(C(C)C)c(=O)[nH]c1=O
Show InChI InChI=1S/C18H24N2O3S/c1-6-7-23-20-17(15(11(2)3)16(21)19-18(20)22)24-14-9-12(4)8-13(5)10-14/h8-11H,6-7H2,1-5H3,(H,19,21,22)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Life Science Research Center

Curated by ChEMBL


Assay Description
Inhibitory effect of the compound on Molony Murine Leukemia virus (mo-MuLv) recombinant reverse transcriptase


J Med Chem 40: 2363-73 (1997)


Article DOI: 10.1021/jm9607921
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%