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PubMed code 9301661

Compile data set for download or QSAR
Found 32 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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 62n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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 118n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50059893
PNG
(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Show SMILES CCOc1c(OC)cc(CCN)cc1OC
Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3
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 177n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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 205n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Antagonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]- rauwolscine radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50059893
PNG
(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Show SMILES CCOc1c(OC)cc(CCN)cc1OC
Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3
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 216n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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 302n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50059891
PNG
(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Show SMILES COc1cc(CCN)cc(OC)c1OC
Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
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 303n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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 311n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Antagonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-rauwolscine radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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 335n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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 368n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
PDB
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 368n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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 523n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50059891
PNG
(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Show SMILES COc1cc(CCN)cc(OC)c1OC
Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
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 551n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50059893
PNG
(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Show SMILES CCOc1c(OC)cc(CCN)cc1OC
Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3
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 555n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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 654n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Antagonist activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50059891
PNG
(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Show SMILES COc1cc(CCN)cc(OC)c1OC
Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
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 795n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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 1.11E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Antagonist activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50059893
PNG
(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Show SMILES CCOc1c(OC)cc(CCN)cc1OC
Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3
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 2.10E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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 2.50E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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 4.44E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Antagonist activity at cloned human 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin radioligand

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50059891
PNG
(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Show SMILES COc1cc(CCN)cc(OC)c1OC
Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
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 5.50E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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 6.20E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50059891
PNG
(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Show SMILES COc1cc(CCN)cc(OC)c1OC
Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
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 6.90E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50059893
PNG
(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Show SMILES CCOc1c(OC)cc(CCN)cc1OC
Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3
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 6.90E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50059893
PNG
(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Show SMILES CCOc1c(OC)cc(CCN)cc1OC
Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3
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n/an/an/an/a 2.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50059893
PNG
(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Show SMILES CCOc1c(OC)cc(CCN)cc1OC
Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3
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n/an/an/an/a 4.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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n/an/an/an/a 2.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50059891
PNG
(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Show SMILES COc1cc(CCN)cc(OC)c1OC
Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
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n/an/an/an/a 4.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50059891
PNG
(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Show SMILES COc1cc(CCN)cc(OC)c1OC
Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
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n/an/an/an/a 2.40E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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n/an/an/an/a 2.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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n/an/an/an/a 3.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast expressing 5-hydroxytryptamine 2A receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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n/an/an/an/a 1.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptor

J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%