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PubMed code 9301675

Compile data set for download or QSAR
Found 53 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Translocator protein


(Rattus norvegicus (rat))		BDBM50060088
PNG
(2-(6-Chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C21H24ClN3O/c1-3-12-24(13-4-2)20(26)14-18-21(16-8-6-5-7-9-16)23-19-11-10-17(22)15-25(18)19/h5-11,15H,3-4,12-14H2,1-2H3
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n/an/a 4n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM22041
PNG
(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23Cl2N3O/c1-3-11-25(12-4-2)20(27)13-18-21(15-5-7-16(22)8-6-15)24-19-10-9-17(23)14-26(18)19/h5-10,14H,3-4,11-13H2,1-2H3
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n/an/a 7.90n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060098
PNG
(CHEMBL420468 | [6-Bromo-2-(4-chloro-phenyl)-imidaz...)
Show SMILES CCCCOC(=O)Cc1c(nc2ccc(Br)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H18BrClN2O2/c1-2-3-10-25-18(24)11-16-19(13-4-7-15(21)8-5-13)22-17-9-6-14(20)12-23(16)17/h4-9,12H,2-3,10-11H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060093
PNG
((6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-ac...)
Show SMILES CCOC(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1
Show InChI InChI=1S/C19H20N2O2/c1-4-23-18(22)11-16-19(15-8-5-13(2)6-9-15)20-17-10-7-14(3)12-21(16)17/h5-10,12H,4,11H2,1-3H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060118
PNG
((6-Bromo-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acet...)
Show SMILES CCOC(=O)Cc1c(nc2ccc(Br)cn12)-c1ccccc1
Show InChI InChI=1S/C17H15BrN2O2/c1-2-22-16(21)10-14-17(12-6-4-3-5-7-12)19-15-9-8-13(18)11-20(14)15/h3-9,11H,2,10H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060108
PNG
(CHEMBL104007 | [6-Chloro-2-(4-chloro-phenyl)-imida...)
Show SMILES CCC(CC)OC(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H20Cl2N2O2/c1-3-16(4-2)26-19(25)11-17-20(13-5-7-14(21)8-6-13)23-18-10-9-15(22)12-24(17)18/h5-10,12,16H,3-4,11H2,1-2H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060128
PNG
(CHEMBL321345 | [8-Chloro-2-(4-chloro-phenyl)-6-tri...)
Show SMILES CCOC(=O)Cc1c(nc2c(Cl)cc(cn12)C(F)(F)F)-c1ccc(Cl)cc1
Show InChI InChI=1S/C18H13Cl2F3N2O2/c1-2-27-15(26)8-14-16(10-3-5-12(19)6-4-10)24-17-13(20)7-11(9-25(14)17)18(21,22)23/h3-7,9H,2,8H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060125
PNG
(CHEMBL319873 | [6,8-Dibromo-2-(4-chloro-phenyl)-im...)
Show SMILES CCOC(=O)Cc1c(nc2c(Br)cc(Br)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H13Br2ClN2O2/c1-2-24-15(23)8-14-16(10-3-5-12(20)6-4-10)21-17-13(19)7-11(18)9-22(14)17/h3-7,9H,2,8H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060129
PNG
(2-(4-Chloro-phenyl)-imidazo[1,2-a]pyridine-3-carbo...)
Show SMILES CCOC(=O)c1c(nc2ccccn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H13ClN2O2/c1-2-21-16(20)15-14(11-6-8-12(17)9-7-11)18-13-5-3-4-10-19(13)15/h3-10H,2H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060117
PNG
(CHEMBL262443 | [6-Bromo-2-(4-chloro-phenyl)-imidaz...)
Show SMILES CCOC(=O)Cc1c(nc2ccc(Br)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H14BrClN2O2/c1-2-23-16(22)9-14-17(11-3-6-13(19)7-4-11)20-15-8-5-12(18)10-21(14)15/h3-8,10H,2,9H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060100
PNG
(CHEMBL107295 | [6,8-Dichloro-2-(4-chloro-phenyl)-i...)
Show SMILES CCOC(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H13Cl3N2O2/c1-2-24-15(23)8-14-16(10-3-5-11(18)6-4-10)21-17-13(20)7-12(19)9-22(14)17/h3-7,9H,2,8H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060130
PNG
(2-(4-Chloro-phenyl)-6-methyl-imidazo[1,2-a]pyridin...)
Show SMILES CCOC(=O)c1c(nc2ccc(C)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H15ClN2O2/c1-3-22-17(21)16-15(12-5-7-13(18)8-6-12)19-14-9-4-11(2)10-20(14)16/h4-10H,3H2,1-2H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060113
PNG
(2-p-Tolyl-imidazo[1,2-a]pyridine-3-carboxylic acid...)
Show SMILES CCOC(=O)c1c(nc2ccccn12)-c1ccc(C)cc1
Show InChI InChI=1S/C17H16N2O2/c1-3-21-17(20)16-15(13-9-7-12(2)8-10-13)18-14-6-4-5-11-19(14)16/h4-11H,3H2,1-2H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060097
PNG
(6-Methyl-2-phenyl-imidazo[1,2-a]pyridine-3-carboxy...)
Show SMILES CCOC(=O)c1c(nc2ccc(C)cn12)-c1ccccc1
Show InChI InChI=1S/C17H16N2O2/c1-3-21-17(20)16-15(13-7-5-4-6-8-13)18-14-10-9-12(2)11-19(14)16/h4-11H,3H2,1-2H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060123
PNG
(6-Chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin...)
Show SMILES CCOC(=O)c1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H12Cl2N2O2/c1-2-22-16(21)15-14(10-3-5-11(17)6-4-10)19-13-8-7-12(18)9-20(13)15/h3-9H,2H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060085
PNG
((6-Nitro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acet...)
Show SMILES CCOC(=O)Cc1c(nc2ccc(cn12)[N+]([O-])=O)-c1ccccc1
Show InChI InChI=1S/C17H15N3O4/c1-2-24-16(21)10-14-17(12-6-4-3-5-7-12)18-15-9-8-13(20(22)23)11-19(14)15/h3-9,11H,2,10H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060120
PNG
((6-Amino-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acet...)
Show SMILES CCOC(=O)Cc1c(nc2ccc(N)cn12)-c1ccccc1
Show InChI InChI=1S/C17H17N3O2/c1-2-22-16(21)10-14-17(12-6-4-3-5-7-12)19-15-9-8-13(18)11-20(14)15/h3-9,11H,2,10,18H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060107
PNG
((6,8-Dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)...)
Show SMILES CCCCOC(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C19H18Cl2N2O2/c1-2-3-9-25-17(24)11-16-18(13-7-5-4-6-8-13)22-19-15(21)10-14(20)12-23(16)19/h4-8,10,12H,2-3,9,11H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060109
PNG
(CHEMBL107905 | [2-(4-Chloro-phenyl)-6-nitro-imidaz...)
Show SMILES CCCCOC(=O)Cc1c(nc2ccc(cn12)[N+]([O-])=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H18ClN3O4/c1-2-3-10-27-18(24)11-16-19(13-4-6-14(20)7-5-13)21-17-9-8-15(23(25)26)12-22(16)17/h4-9,12H,2-3,10-11H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060110
PNG
(2-Phenyl-imidazo[1,2-a]pyridine-3-carboxylic acid ...)
Show SMILES CCOC(=O)c1c(nc2ccccn12)-c1ccccc1
Show InChI InChI=1S/C16H14N2O2/c1-2-20-16(19)15-14(12-8-4-3-5-9-12)17-13-10-6-7-11-18(13)15/h3-11H,2H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060104
PNG
(2-[6-Bromo-2-(4-chloro-phenyl)-imidazo[1,2-a]pyrid...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(Br)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23BrClN3O/c1-3-11-25(12-4-2)20(27)13-18-21(15-5-8-17(23)9-6-15)24-19-10-7-16(22)14-26(18)19/h5-10,14H,3-4,11-13H2,1-2H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060131
PNG
(2-(6,8-Dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-y...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C21H23Cl2N3O/c1-3-10-25(11-4-2)19(27)13-18-20(15-8-6-5-7-9-15)24-21-17(23)12-16(22)14-26(18)21/h5-9,12,14H,3-4,10-11,13H2,1-2H3
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n/an/a 12n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060121
PNG
(2-(6-Nitro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N,...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(cn12)[N+]([O-])=O)-c1ccccc1
Show InChI InChI=1S/C21H24N4O3/c1-3-12-23(13-4-2)20(26)14-18-21(16-8-6-5-7-9-16)22-19-11-10-17(25(27)28)15-24(18)19/h5-11,15H,3-4,12-14H2,1-2H3
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n/an/a 12n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060115
PNG
(2-(6-Bromo-8-methyl-2-phenyl-imidazo[1,2-a]pyridin...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(C)cc(Br)cn12)-c1ccccc1
Show InChI InChI=1S/C22H26BrN3O/c1-4-11-25(12-5-2)20(27)14-19-21(17-9-7-6-8-10-17)24-22-16(3)13-18(23)15-26(19)22/h6-10,13,15H,4-5,11-12,14H2,1-3H3
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n/an/a 14n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060102
PNG
(2-(6-Bromo-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N,...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(Br)cn12)-c1ccccc1
Show InChI InChI=1S/C21H24BrN3O/c1-3-12-24(13-4-2)20(26)14-18-21(16-8-6-5-7-9-16)23-19-11-10-17(22)15-25(18)19/h5-11,15H,3-4,12-14H2,1-2H3
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n/an/a 15n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060132
PNG
(2-(8-Bromo-6-methyl-2-phenyl-imidazo[1,2-a]pyridin...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Br)cc(C)cn12)-c1ccccc1
Show InChI InChI=1S/C22H26BrN3O/c1-4-11-25(12-5-2)20(27)14-19-21(17-9-7-6-8-10-17)24-22-18(23)13-16(3)15-26(19)22/h6-10,13,15H,4-5,11-12,14H2,1-3H3
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n/an/a 19n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060101
PNG
(2-[6-Chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyri...)
Show SMILES Clc1ccc(cc1)-c1nc2ccc(Cl)cn2c1CC(=O)N1CCCCC1
Show InChI InChI=1S/C20H19Cl2N3O/c21-15-6-4-14(5-7-15)20-17(12-19(26)24-10-2-1-3-11-24)25-13-16(22)8-9-18(25)23-20/h4-9,13H,1-3,10-12H2
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n/an/a 19n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060095
PNG
(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H22Cl3N3O/c1-3-9-26(10-4-2)19(28)12-18-20(14-5-7-15(22)8-6-14)25-21-17(24)11-16(23)13-27(18)21/h5-8,11,13H,3-4,9-10,12H2,1-2H3
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n/an/a 20n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060119
PNG
(2-(6-Iodo-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N,N...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(I)cn12)-c1ccccc1
Show InChI InChI=1S/C21H24IN3O/c1-3-12-24(13-4-2)20(26)14-18-21(16-8-6-5-7-9-16)23-19-11-10-17(22)15-25(18)19/h5-11,15H,3-4,12-14H2,1-2H3
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n/an/a 23n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060122
PNG
(2-(6-Methoxy-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(OC)cn12)-c1ccccc1
Show InChI InChI=1S/C22H27N3O2/c1-4-13-24(14-5-2)21(26)15-19-22(17-9-7-6-8-10-17)23-20-12-11-18(27-3)16-25(19)20/h6-12,16H,4-5,13-15H2,1-3H3
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n/an/a 34n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060127
PNG
(2-(6-Methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccccc1
Show InChI InChI=1S/C22H27N3O/c1-4-13-24(14-5-2)21(26)15-19-22(18-9-7-6-8-10-18)23-20-12-11-17(3)16-25(19)20/h6-12,16H,4-5,13-15H2,1-3H3
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n/an/a 35n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060105
PNG
(2-[8-Chloro-2-(4-chloro-phenyl)-6-trifluoromethyl-...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(cn12)C(F)(F)F)-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H22Cl2F3N3O/c1-3-9-29(10-4-2)19(31)12-18-20(14-5-7-16(23)8-6-14)28-21-17(24)11-15(13-30(18)21)22(25,26)27/h5-8,11,13H,3-4,9-10,12H2,1-2H3
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n/an/a 37n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060126
PNG
(2-[6,8-Dibromo-2-(4-chloro-phenyl)-imidazo[1,2-a]p...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Br)cc(Br)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H22Br2ClN3O/c1-3-9-26(10-4-2)19(28)12-18-20(14-5-7-16(24)8-6-14)25-21-17(23)11-15(22)13-27(18)21/h5-8,11,13H,3-4,9-10,12H2,1-2H3
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n/an/a 55n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060114
PNG
(2-(2-Phenyl-imidazo[1,2-a]pyridin-3-yl)-N,N-diprop...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccccn12)-c1ccccc1
Show InChI InChI=1S/C21H25N3O/c1-3-13-23(14-4-2)20(25)16-18-21(17-10-6-5-7-11-17)22-19-12-8-9-15-24(18)19/h5-12,15H,3-4,13-14,16H2,1-2H3
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n/an/a 80n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060124
PNG
(2-[6-Chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyri...)
Show SMILES Clc1ccc(cc1)-c1nc2ccc(Cl)cn2c1CC(=O)N1CCCC1
Show InChI InChI=1S/C19H17Cl2N3O/c20-14-5-3-13(4-6-14)19-16(11-18(25)23-9-1-2-10-23)24-12-15(21)7-8-17(24)22-19/h3-8,12H,1-2,9-11H2
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n/an/a 287n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060090
PNG
(6-Chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin...)
Show SMILES CCCN(CCC)C(=O)c1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H21Cl2N3O/c1-3-11-24(12-4-2)20(26)19-18(14-5-7-15(21)8-6-14)23-17-10-9-16(22)13-25(17)19/h5-10,13H,3-4,11-12H2,1-2H3
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n/an/a 426n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060111
PNG
(6-Chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin...)
Show SMILES CCN(CC)C(=O)c1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C18H17Cl2N3O/c1-3-22(4-2)18(24)17-16(12-5-7-13(19)8-6-12)21-15-10-9-14(20)11-23(15)17/h5-11H,3-4H2,1-2H3
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n/an/a 2.04E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060103
PNG
(3-(6-Chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N...)
Show SMILES CCCN(CCC)C(=O)CCc1c(nc2ccc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C22H26ClN3O/c1-3-14-25(15-4-2)21(27)13-11-19-22(17-8-6-5-7-9-17)24-20-12-10-18(23)16-26(19)20/h5-10,12,16H,3-4,11,13-15H2,1-2H3
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n/an/a 3.27E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM26266
PNG
(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1
Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3
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n/an/a 4.70E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060094
PNG
((6-Chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-ace...)
Show SMILES CCCCOC(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C19H19ClN2O2/c1-2-3-11-24-18(23)12-16-19(14-7-5-4-6-8-14)21-17-10-9-15(20)13-22(16)17/h4-10,13H,2-3,11-12H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060099
PNG
(6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridine-3-carbox...)
Show SMILES CCOC(=O)c1c(nc2ccc(C)cn12)-c1ccc(C)cc1
Show InChI InChI=1S/C18H18N2O2/c1-4-22-18(21)17-16(14-8-5-12(2)6-9-14)19-15-10-7-13(3)11-20(15)17/h5-11H,4H2,1-3H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060089
PNG
((6-Methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-ace...)
Show SMILES CCOC(=O)Cc1c(nc2ccc(C)cn12)-c1ccccc1
Show InChI InChI=1S/C18H18N2O2/c1-3-22-17(21)11-15-18(14-7-5-4-6-8-14)19-16-10-9-13(2)12-20(15)16/h4-10,12H,3,11H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060112
PNG
((6-Methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-ace...)
Show SMILES CCCCOC(=O)Cc1c(nc2ccc(C)cn12)-c1ccccc1
Show InChI InChI=1S/C20H22N2O2/c1-3-4-12-24-19(23)13-17-20(16-8-6-5-7-9-16)21-18-11-10-15(2)14-22(17)18/h5-11,14H,3-4,12-13H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060087
PNG
(CHEMBL322388 | [6-Chloro-2-(4-chloro-phenyl)-imida...)
Show SMILES CCOC(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H14Cl2N2O2/c1-2-23-16(22)9-14-17(11-3-5-12(18)6-4-11)20-15-8-7-13(19)10-21(14)15/h3-8,10H,2,9H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060106
PNG
(3-(6-Chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-p...)
Show SMILES CCCCOC(=O)CCc1c(nc2ccc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C20H21ClN2O2/c1-2-3-13-25-19(24)12-10-17-20(15-7-5-4-6-8-15)22-18-11-9-16(21)14-23(17)18/h4-9,11,14H,2-3,10,12-13H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060086
PNG
(CHEMBL108259 | [6-Chloro-2-(4-chloro-phenyl)-imida...)
Show SMILES CCCCOC(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H18Cl2N2O2/c1-2-3-10-25-18(24)11-16-19(13-4-6-14(20)7-5-13)22-17-9-8-15(21)12-23(16)17/h4-9,12H,2-3,10-11H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060096
PNG
((6-Chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-ace...)
Show SMILES CCOC(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C17H15ClN2O2/c1-2-22-16(21)10-14-17(12-6-4-3-5-7-12)19-15-9-8-13(18)11-20(14)15/h3-9,11H,2,10H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060091
PNG
(3-(6-Chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-p...)
Show SMILES CCOC(=O)CCc1c(nc2ccc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C18H17ClN2O2/c1-2-23-17(22)11-9-15-18(13-6-4-3-5-7-13)20-16-10-8-14(19)12-21(15)16/h3-8,10,12H,2,9,11H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060092
PNG
(CHEMBL104537 | [6-Chloro-2-(4-chloro-phenyl)-imida...)
Show SMILES Clc1ccc(cc1)-c1nc2ccc(Cl)cn2c1C(=O)N1CCCC1
Show InChI InChI=1S/C18H15Cl2N3O/c19-13-5-3-12(4-6-13)16-17(18(24)22-9-1-2-10-22)23-11-14(20)7-8-15(23)21-16/h3-8,11H,1-2,9-10H2
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Translocator protein


(Rattus norvegicus (rat))		BDBM50060116
PNG
(6-Chloro-2-phenyl-imidazo[1,2-a]pyridine-3-carboxy...)
Show SMILES CCOC(=O)c1c(nc2ccc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C16H13ClN2O2/c1-2-21-16(20)15-14(11-6-4-3-5-7-11)18-13-9-8-12(17)10-19(13)15/h3-10H,2H2,1H3
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Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptor

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2


(Homo sapiens (Human))		BDBM26266
PNG
(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1
Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3
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n/an/an/an/a 1.80E+9n/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Potentiation of GABA-evoked Cl- currents in Xenopus oocytes expressing human alpha-2-beta-2-gamma-2 subunits

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2


(Homo sapiens (Human))		BDBM50060088
PNG
(2-(6-Chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C21H24ClN3O/c1-3-12-24(13-4-2)20(26)14-18-21(16-8-6-5-7-9-16)23-19-11-10-17(22)15-25(18)19/h5-11,15H,3-4,12-14H2,1-2H3
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n/an/an/an/a 1.30E+9n/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Potentiation of GABA-evoked Cl- currents in Xenopus oocytes expressing human alpha-2-beta-2-gamma-2 subunits

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2


(Homo sapiens (Human))		BDBM50060124
PNG
(2-[6-Chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyri...)
Show SMILES Clc1ccc(cc1)-c1nc2ccc(Cl)cn2c1CC(=O)N1CCCC1
Show InChI InChI=1S/C19H17Cl2N3O/c20-14-5-3-13(4-6-14)19-16(11-18(25)23-9-1-2-10-23)24-12-15(21)7-8-17(24)22-19/h3-8,12H,1-2,9-11H2
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n/an/an/an/a 6.60E+9n/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Potentiation of GABA-evoked Cl- currents in Xenopus oocytes expressing human alpha-2-beta-2-gamma-2 subunits

J Med Chem 40: 3109-18 (1997)


Article DOI: 10.1021/jm970112+
BindingDB Entry DOI: 10.7270/Q2PN9699
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%