Affinity Data by PubMed id=9651168

PubMed code 9651168

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50065353 ((S)-2-Amino-N-((6S,12R)-6-benzyl-1-methyl-5,8,11-t...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor mu 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50065353 ((S)-2-Amino-N-((6S,12R)-6-benzyl-1-methyl-5,8,11-t...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor delta 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50001683 (13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor delta 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM21015 ((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor mu 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor mu 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor delta 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor kappa 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50065353 ((S)-2-Amino-N-((6S,12R)-6-benzyl-1-methyl-5,8,11-t...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor kappa 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM21015 ((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor delta 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM21015 ((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor kappa 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50001683 (13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor kappa 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50001683 (13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description In vitro potency was measured against human Opioid receptor mu 1				J Med Chem 41: 2631-5 (1998) Article DOI: 10.1021/jm970861r BindingDB Entry DOI: 10.7270/Q21N81TP
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%