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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coagulation factor X (Homo sapiens (Human)) | BDBM17277 ((Z,Z)BABCH | 4-{[(1Z,3Z)-3-[(4-carbamimidoylphenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor X | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Homo sapiens (Human)) | BDBM50066616 ((Z,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor X | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine protease 1 (Bos taurus (bovine)) | BDBM50066615 ((E,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine protease 1 (Bos taurus (bovine)) | BDBM17277 ((Z,Z)BABCH | 4-{[(1Z,3Z)-3-[(4-carbamimidoylphenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Serine protease 1 (Bos taurus (bovine)) | BDBM50066616 ((Z,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50066615 ((E,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Homo sapiens (Human)) | BDBM50066613 ((E,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor X | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Homo sapiens (Human)) | BDBM50066615 ((E,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor X | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine protease 1 (Bos taurus (bovine)) | BDBM50066613 ((E,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine protease 1 (Bos taurus (bovine)) | BDBM50066614 ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine protease 1 (Bos taurus (bovine)) | BDBM50066612 ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM17277 ((Z,Z)BABCH | 4-{[(1Z,3Z)-3-[(4-carbamimidoylphenyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50066613 ((E,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Homo sapiens (Human)) | BDBM50066612 ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor X | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50066616 ((Z,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50066612 ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50066614 ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin. | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Homo sapiens (Human)) | BDBM50066614 ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor X | J Med Chem 41: 3551-6 (1998) Article DOI: 10.1021/jm980281+ BindingDB Entry DOI: 10.7270/Q2QJ7GFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
