Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85447 (Epoxy analogue, I(a)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | 7.00E+3 | -30.6 | 5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85448 (Epoxy analogue, I(b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.10E+4 | -25.0 | 1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85450 (Epithioamino acid analogue, II(a)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+5 | -23.7 | 1.40E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85449 (Epoxy analogue, I(c)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.05E+5 | -23.6 | 1.10E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85451 (Epithioamino acid analogue, II(b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.40E+5 | -22.9 | 3.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85452 (Epithioamino acid analogue, II(c)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.40E+5 | -22.9 | 4.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair |