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PubMed code 9804688

Compile data set for download or QSAR
Found 51 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(1A) dopamine receptor


(RAT)		BDBM82247
PNG
(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)
Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r|
Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1
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n/an/a 4.30n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50067814
PNG
(17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,1...)
Show SMILES CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(O)cc12 |TLB:3:4:7:13.12.11.10,THB:13:6:8.9:2.3,1:2:8.9:6.5,10:8:6.5:2.3|
Show InChI InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11?,12-,16-,19?/m1/s1
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n/an/a 40n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against serotonin transporter using RTI-55 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50067811
PNG
(7-Ethyl-9-phenyl-6,7,8,9-tetrahydro-5H-10-thia-7-a...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C20H21NS/c1-2-21-13-12-17-16-10-6-7-11-19(16)22-20(17)18(14-21)15-8-4-3-5-9-15/h3-11,18H,2,12-14H2,1H3
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n/an/a 140n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against dopamine transporter using WIN-35428 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067814
PNG
(17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,1...)
Show SMILES CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(O)cc12 |TLB:3:4:7:13.12.11.10,THB:13:6:8.9:2.3,1:2:8.9:6.5,10:8:6.5:2.3|
Show InChI InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11?,12-,16-,19?/m1/s1
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n/an/a 160n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity against Opioid receptor mu 1 in thalamus using [3H]DAMGO as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50067809
PNG
(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Show SMILES CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C19H20N2/c1-21-12-11-16-15-9-5-6-10-18(15)20-19(16)17(13-21)14-7-3-2-4-8-14/h2-10,17,20H,11-13H2,1H3
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n/an/a 180n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against dopamine transporter using WIN-35428 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50067809
PNG
(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Show SMILES CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C19H20N2/c1-21-12-11-16-15-9-5-6-10-18(15)20-19(16)17(13-21)14-7-3-2-4-8-14/h2-10,17,20H,11-13H2,1H3
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n/an/a 190n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against serotonin transporter using RTI-55 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50067816
PNG
(9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1
Show InChI InChI=1S/C20H20BrNS/c1-2-22-11-10-17-16-8-3-4-9-19(16)23-20(17)18(13-22)14-6-5-7-15(21)12-14/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 210n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against dopamine transporter using WIN-35428 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50067810
PNG
(9-(3,4-Dichloro-phenyl)-7-ethyl-6,7,8,9-tetrahydro...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H19Cl2NS/c1-2-23-10-9-15-14-5-3-4-6-19(14)24-20(15)16(12-23)13-7-8-17(21)18(22)11-13/h3-8,11,16H,2,9-10,12H2,1H3
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n/an/a 250n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against dopamine transporter using WIN-35428 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50067815
PNG
(7-Ethyl-9-(3-nitro-phenyl)-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H20N2O2S/c1-2-21-11-10-17-16-8-3-4-9-19(16)25-20(17)18(13-21)14-6-5-7-15(12-14)22(23)24/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 250n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against dopamine transporter using WIN-35428 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50067811
PNG
(7-Ethyl-9-phenyl-6,7,8,9-tetrahydro-5H-10-thia-7-a...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C20H21NS/c1-2-21-13-12-17-16-10-6-7-11-19(16)22-20(17)18(14-21)15-8-4-3-5-9-15/h3-11,18H,2,12-14H2,1H3
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n/an/a 300n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against serotonin transporter using RTI-55 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50067817
PNG
(7,8-Dimethoxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro...)
Show SMILES COc1cc2CCN(C)CC(c3ccccc3)c2cc1OC
Show InChI InChI=1S/C19H23NO2/c1-20-10-9-15-11-18(21-2)19(22-3)12-16(15)17(13-20)14-7-5-4-6-8-14/h4-8,11-12,17H,9-10,13H2,1-3H3
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n/an/a 491n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50206577
PNG
(10-methoxyibogamine | CHEMBL222287 | IBOGAINE)
Show SMILES CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCc1c3[nH]c2ccc(OC)cc12 |r,TLB:22:12:7:5.4.9,14:13:7:5.4.9,THB:10:8:5.6:2.3,1:2:5.6:8.9,13:6:2.3:8.9|
Show InChI InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13-,17-,20-/m0/s1
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n/an/a 590n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against serotonin transporter using RTI-55 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Rattus norvegicus (Rat))		BDBM50067811
PNG
(7-Ethyl-9-phenyl-6,7,8,9-tetrahydro-5H-10-thia-7-a...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C20H21NS/c1-2-21-13-12-17-16-10-6-7-11-19(16)22-20(17)18(14-21)15-8-4-3-5-9-15/h3-11,18H,2,12-14H2,1H3
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n/an/a 600n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Rattus norvegicus (Rat))		BDBM50067815
PNG
(7-Ethyl-9-(3-nitro-phenyl)-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H20N2O2S/c1-2-21-11-10-17-16-8-3-4-9-19(16)25-20(17)18(13-21)14-6-5-7-15(12-14)22(23)24/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 600n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50067815
PNG
(7-Ethyl-9-(3-nitro-phenyl)-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H20N2O2S/c1-2-21-11-10-17-16-8-3-4-9-19(16)25-20(17)18(13-21)14-6-5-7-15(12-14)22(23)24/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 1.10E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against serotonin transporter using RTI-55 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50067810
PNG
(9-(3,4-Dichloro-phenyl)-7-ethyl-6,7,8,9-tetrahydro...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H19Cl2NS/c1-2-23-10-9-15-14-5-3-4-6-19(14)24-20(15)16(12-23)13-7-8-17(21)18(22)11-13/h3-8,11,16H,2,9-10,12H2,1H3
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n/an/a 1.20E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against serotonin transporter using RTI-55 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067811
PNG
(7-Ethyl-9-phenyl-6,7,8,9-tetrahydro-5H-10-thia-7-a...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C20H21NS/c1-2-21-13-12-17-16-10-6-7-11-19(16)22-20(17)18(14-21)15-8-4-3-5-9-15/h3-11,18H,2,12-14H2,1H3
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n/an/a 1.30E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Opioid receptor kappa 1 in insular Ctx using [3H]U-69593 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Rattus norvegicus (Rat))		BDBM50067816
PNG
(9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1
Show InChI InChI=1S/C20H20BrNS/c1-2-22-11-10-17-16-8-3-4-9-19(16)23-20(17)18(13-22)14-6-5-7-15(21)12-14/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Rattus norvegicus (Rat))		BDBM50067810
PNG
(9-(3,4-Dichloro-phenyl)-7-ethyl-6,7,8,9-tetrahydro...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H19Cl2NS/c1-2-23-10-9-15-14-5-3-4-6-19(14)24-20(15)16(12-23)13-7-8-17(21)18(22)11-13/h3-8,11,16H,2,9-10,12H2,1H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067811
PNG
(7-Ethyl-9-phenyl-6,7,8,9-tetrahydro-5H-10-thia-7-a...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C20H21NS/c1-2-21-13-12-17-16-10-6-7-11-19(16)22-20(17)18(14-21)15-8-4-3-5-9-15/h3-11,18H,2,12-14H2,1H3
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n/an/a 2.20E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity against Opioid receptor mu 1 in thalamus using [3H]DAMGO as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50067811
PNG
(7-Ethyl-9-phenyl-6,7,8,9-tetrahydro-5H-10-thia-7-a...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C20H21NS/c1-2-21-13-12-17-16-10-6-7-11-19(16)22-20(17)18(14-21)15-8-4-3-5-9-15/h3-11,18H,2,12-14H2,1H3
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n/an/a 3.00E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067809
PNG
(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Show SMILES CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C19H20N2/c1-21-12-11-16-15-9-5-6-10-18(15)20-19(16)17(13-21)14-7-3-2-4-8-14/h2-10,17,20H,11-13H2,1H3
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n/an/a 3.10E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity against Opioid receptor mu 1 in thalamus using [3H]DAMGO as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067815
PNG
(7-Ethyl-9-(3-nitro-phenyl)-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H20N2O2S/c1-2-21-11-10-17-16-8-3-4-9-19(16)25-20(17)18(13-21)14-6-5-7-15(12-14)22(23)24/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 3.10E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity against Opioid receptor mu 1 in thalamus using [3H]DAMGO as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50067815
PNG
(7-Ethyl-9-(3-nitro-phenyl)-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H20N2O2S/c1-2-21-11-10-17-16-8-3-4-9-19(16)25-20(17)18(13-21)14-6-5-7-15(12-14)22(23)24/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 3.10E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D2 in striatum using [3H]YM-09151-2 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50067814
PNG
(17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,1...)
Show SMILES CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(O)cc12 |TLB:3:4:7:13.12.11.10,THB:13:6:8.9:2.3,1:2:8.9:6.5,10:8:6.5:2.3|
Show InChI InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11?,12-,16-,19?/m1/s1
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n/an/a 3.35E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against dopamine transporter using WIN-35428 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50067816
PNG
(9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1
Show InChI InChI=1S/C20H20BrNS/c1-2-22-11-10-17-16-8-3-4-9-19(16)23-20(17)18(13-22)14-6-5-7-15(21)12-14/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 3.50E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D2 in striatum using [3H]YM-09151-2 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50206577
PNG
(10-methoxyibogamine | CHEMBL222287 | IBOGAINE)
Show SMILES CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCc1c3[nH]c2ccc(OC)cc12 |r,TLB:22:12:7:5.4.9,14:13:7:5.4.9,THB:10:8:5.6:2.3,1:2:5.6:8.9,13:6:2.3:8.9|
Show InChI InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13-,17-,20-/m0/s1
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n/an/a 3.76E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity against Opioid receptor mu 1 in thalamus using [3H]DAMGO as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50206577
PNG
(10-methoxyibogamine | CHEMBL222287 | IBOGAINE)
Show SMILES CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCc1c3[nH]c2ccc(OC)cc12 |r,TLB:22:12:7:5.4.9,14:13:7:5.4.9,THB:10:8:5.6:2.3,1:2:5.6:8.9,13:6:2.3:8.9|
Show InChI InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13-,17-,20-/m0/s1
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n/an/a 4.11E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against dopamine transporter using WIN-35428 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Rattus norvegicus (Rat))		BDBM50067809
PNG
(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Show SMILES CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C19H20N2/c1-21-12-11-16-15-9-5-6-10-18(15)20-19(16)17(13-21)14-7-3-2-4-8-14/h2-10,17,20H,11-13H2,1H3
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n/an/a 4.20E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067814
PNG
(17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,1...)
Show SMILES CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(O)cc12 |TLB:3:4:7:13.12.11.10,THB:13:6:8.9:2.3,1:2:8.9:6.5,10:8:6.5:2.3|
Show InChI InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11?,12-,16-,19?/m1/s1
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n/an/a 4.24E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Opioid receptor kappa 1 in insular Ctx using [3H]U-69593 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50067816
PNG
(9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1
Show InChI InChI=1S/C20H20BrNS/c1-2-22-11-10-17-16-8-3-4-9-19(16)23-20(17)18(13-22)14-6-5-7-15(21)12-14/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 4.30E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against serotonin transporter using RTI-55 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067816
PNG
(9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1
Show InChI InChI=1S/C20H20BrNS/c1-2-22-11-10-17-16-8-3-4-9-19(16)23-20(17)18(13-22)14-6-5-7-15(21)12-14/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity against Opioid receptor mu 1 in thalamus using [3H]DAMGO as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50067811
PNG
(7-Ethyl-9-phenyl-6,7,8,9-tetrahydro-5H-10-thia-7-a...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C20H21NS/c1-2-21-13-12-17-16-10-6-7-11-19(16)22-20(17)18(14-21)15-8-4-3-5-9-15/h3-11,18H,2,12-14H2,1H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D2 in striatum using [3H]YM-09151-2 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50067810
PNG
(9-(3,4-Dichloro-phenyl)-7-ethyl-6,7,8,9-tetrahydro...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H19Cl2NS/c1-2-23-10-9-15-14-5-3-4-6-19(14)24-20(15)16(12-23)13-7-8-17(21)18(22)11-13/h3-8,11,16H,2,9-10,12H2,1H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D2 in striatum using [3H]YM-09151-2 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50067815
PNG
(7-Ethyl-9-(3-nitro-phenyl)-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H20N2O2S/c1-2-21-11-10-17-16-8-3-4-9-19(16)25-20(17)18(13-21)14-6-5-7-15(12-14)22(23)24/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50067816
PNG
(9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1
Show InChI InChI=1S/C20H20BrNS/c1-2-22-11-10-17-16-8-3-4-9-19(16)23-20(17)18(13-22)14-6-5-7-15(21)12-14/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50206577
PNG
(10-methoxyibogamine | CHEMBL222287 | IBOGAINE)
Show SMILES CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCc1c3[nH]c2ccc(OC)cc12 |r,TLB:22:12:7:5.4.9,14:13:7:5.4.9,THB:10:8:5.6:2.3,1:2:5.6:8.9,13:6:2.3:8.9|
Show InChI InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13-,17-,20-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Rattus norvegicus (Rat))		BDBM50206577
PNG
(10-methoxyibogamine | CHEMBL222287 | IBOGAINE)
Show SMILES CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCc1c3[nH]c2ccc(OC)cc12 |r,TLB:22:12:7:5.4.9,14:13:7:5.4.9,THB:10:8:5.6:2.3,1:2:5.6:8.9,13:6:2.3:8.9|
Show InChI InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13-,17-,20-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50067814
PNG
(17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,1...)
Show SMILES CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(O)cc12 |TLB:3:4:7:13.12.11.10,THB:13:6:8.9:2.3,1:2:8.9:6.5,10:8:6.5:2.3|
Show InChI InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11?,12-,16-,19?/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50206577
PNG
(10-methoxyibogamine | CHEMBL222287 | IBOGAINE)
Show SMILES CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCc1c3[nH]c2ccc(OC)cc12 |r,TLB:22:12:7:5.4.9,14:13:7:5.4.9,THB:10:8:5.6:2.3,1:2:5.6:8.9,13:6:2.3:8.9|
Show InChI InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13-,17-,20-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D2 in striatum using [3H]YM-09151-2 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50067814
PNG
(17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,1...)
Show SMILES CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(O)cc12 |TLB:3:4:7:13.12.11.10,THB:13:6:8.9:2.3,1:2:8.9:6.5,10:8:6.5:2.3|
Show InChI InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11?,12-,16-,19?/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D2 in striatum using [3H]YM-09151-2 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Rattus norvegicus (Rat))		BDBM50067814
PNG
(17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,1...)
Show SMILES CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(O)cc12 |TLB:3:4:7:13.12.11.10,THB:13:6:8.9:2.3,1:2:8.9:6.5,10:8:6.5:2.3|
Show InChI InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11?,12-,16-,19?/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067816
PNG
(9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1
Show InChI InChI=1S/C20H20BrNS/c1-2-22-11-10-17-16-8-3-4-9-19(16)23-20(17)18(13-22)14-6-5-7-15(21)12-14/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 1.25E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Opioid receptor kappa 1 in insular Ctx using [3H]U-69593 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067810
PNG
(9-(3,4-Dichloro-phenyl)-7-ethyl-6,7,8,9-tetrahydro...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H19Cl2NS/c1-2-23-10-9-15-14-5-3-4-6-19(14)24-20(15)16(12-23)13-7-8-17(21)18(22)11-13/h3-8,11,16H,2,9-10,12H2,1H3
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n/an/a 1.59E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Opioid receptor kappa 1 in insular Ctx using [3H]U-69593 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067815
PNG
(7-Ethyl-9-(3-nitro-phenyl)-6,7,8,9-tetrahydro-5H-1...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H20N2O2S/c1-2-21-11-10-17-16-8-3-4-9-19(16)25-20(17)18(13-21)14-6-5-7-15(12-14)22(23)24/h3-9,12,18H,2,10-11,13H2,1H3
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n/an/a 1.62E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Opioid receptor kappa 1 in insular Ctx using [3H]U-69593 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50067809
PNG
(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Show SMILES CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C19H20N2/c1-21-12-11-16-15-9-5-6-10-18(15)20-19(16)17(13-21)14-7-3-2-4-8-14/h2-10,17,20H,11-13H2,1H3
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n/an/a 2.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067809
PNG
(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Show SMILES CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C19H20N2/c1-21-12-11-16-15-9-5-6-10-18(15)20-19(16)17(13-21)14-7-3-2-4-8-14/h2-10,17,20H,11-13H2,1H3
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n/an/a 2.12E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Opioid receptor kappa 1 in insular Ctx using [3H]U-69593 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50206577
PNG
(10-methoxyibogamine | CHEMBL222287 | IBOGAINE)
Show SMILES CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCc1c3[nH]c2ccc(OC)cc12 |r,TLB:22:12:7:5.4.9,14:13:7:5.4.9,THB:10:8:5.6:2.3,1:2:5.6:8.9,13:6:2.3:8.9|
Show InChI InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13-,17-,20-/m0/s1
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Opioid receptor kappa 1 in insular Ctx using [3H]U-69593 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50067809
PNG
(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Show SMILES CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1
Show InChI InChI=1S/C19H20N2/c1-21-12-11-16-15-9-5-6-10-18(15)20-19(16)17(13-21)14-7-3-2-4-8-14/h2-10,17,20H,11-13H2,1H3
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n/an/a 2.72E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
relative affinity against Dopamine receptor D2 in striatum using [3H]YM-09151-2 as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50067810
PNG
(9-(3,4-Dichloro-phenyl)-7-ethyl-6,7,8,9-tetrahydro...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H19Cl2NS/c1-2-23-10-9-15-14-5-3-4-6-19(14)24-20(15)16(12-23)13-7-8-17(21)18(22)11-13/h3-8,11,16H,2,9-10,12H2,1H3
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n/an/a 5.45E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity against Opioid receptor mu 1 in thalamus using [3H]DAMGO as radioligand

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50067810
PNG
(9-(3,4-Dichloro-phenyl)-7-ethyl-6,7,8,9-tetrahydro...)
Show SMILES CCN1CCc2c(sc3ccccc23)C(C1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H19Cl2NS/c1-2-23-10-9-15-14-5-3-4-6-19(14)24-20(15)16(12-23)13-7-8-17(21)18(22)11-13/h3-8,11,16H,2,9-10,12H2,1H3
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n/an/a 7.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390

J Med Chem 41: 4486-91 (1998)


Article DOI: 10.1021/jm980156y
BindingDB Entry DOI: 10.7270/Q2708230
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%