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PubMed code 9822540

Compile data set for download or QSAR
Found 70 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068071
PNG
(CHEMBL2370908 | SRIF)
Show SMILES [H][C@]1(NC(=O)[C@@H](N)CCCCNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O
Show InChI InChI=1S/C76H104N18O19S2/c1-41(78)64(100)83-37-61(99)84-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-65(101)49(79)26-16-18-30-81-66(102)55(34-47-36-82-50-27-14-13-25-48(47)50)88-69(105)53(32-45-21-9-5-10-22-45)86-68(104)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-67(103)51(85-73(58)109)28-15-17-29-77/h4-14,19-25,27,36,41-43,49,51-59,62-63,82,95-97H,15-18,26,28-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,81,102)(H,83,100)(H,84,99)(H,85,109)(H,86,104)(H,87,106)(H,88,105)(H,89,103)(H,90,110)(H,91,111)(H,92,108)(H,93,101)(H,94,107)(H,112,113)/t41-,42+,43+,49-,51+,52+,53-,54-,55+,56-,57-,58+,59-,62-,63-/m0/s1
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 0.200n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50272772
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 |r|
Show InChI InChI=1S/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29-,34-,36+,37+,38-,39-,40+,41+,42+/m1/s1
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 0.300n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068063
PNG
((12S,15R,18S)-9-(4-Amino-butyl)-3-benzyl-15-(4-hyd...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O
Show InChI InChI=1S/C44H56N8O7/c1-26(2)38-43(58)50-37(23-28-12-6-5-7-13-28)44(59)52(4)27(3)39(54)48-35(22-29-17-19-31(53)20-18-29)41(56)49-36(24-30-25-46-33-15-9-8-14-32(30)33)42(57)47-34(40(55)51-38)16-10-11-21-45/h5-9,12-15,17-20,25-27,34-38,46,53H,10-11,16,21-24,45H2,1-4H3,(H,47,57)(H,48,54)(H,49,56)(H,50,58)(H,51,55)/t27-,34-,35+,36-,37-,38-/m0/s1
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 0.300n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068071
PNG
(CHEMBL2370908 | SRIF)
Show SMILES [H][C@]1(NC(=O)[C@@H](N)CCCCNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O
Show InChI InChI=1S/C76H104N18O19S2/c1-41(78)64(100)83-37-61(99)84-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-65(101)49(79)26-16-18-30-81-66(102)55(34-47-36-82-50-27-14-13-25-48(47)50)88-69(105)53(32-45-21-9-5-10-22-45)86-68(104)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-67(103)51(85-73(58)109)28-15-17-29-77/h4-14,19-25,27,36,41-43,49,51-59,62-63,82,95-97H,15-18,26,28-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,81,102)(H,83,100)(H,84,99)(H,85,109)(H,86,104)(H,87,106)(H,88,105)(H,89,103)(H,90,110)(H,91,111)(H,92,108)(H,93,101)(H,94,107)(H,112,113)/t41-,42+,43+,49-,51+,52+,53-,54-,55+,56-,57-,58+,59-,62-,63-/m0/s1
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 1.40n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068039
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H25BrCl2N6S/c23-17-5-7-21(29-12-17)31(14-16-4-6-19(24)20(25)11-16)10-2-9-28-22(32)27-8-1-3-18-13-26-15-30-18/h4-7,11-13,15H,1-3,8-10,14H2,(H,26,30)(H2,27,28,32)
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 6n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068043
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=O)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C21H23BrCl2N6O/c22-16-4-6-20(28-11-16)30(13-15-3-5-18(23)19(24)10-15)9-8-27-21(31)26-7-1-2-17-12-25-14-29-17/h3-6,10-12,14H,1-2,7-9,13H2,(H,25,29)(H2,26,27,31)
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 14n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068067
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-naphthalen-1-ylmethyl...)
Show SMILES Brc1ccc(nc1)N(CCCNC(=S)NCCCc1cnc[nH]1)Cc1cccc2ccccc12
Show InChI InChI=1S/C26H29BrN6S/c27-22-11-12-25(31-16-22)33(18-21-8-3-7-20-6-1-2-10-24(20)21)15-5-14-30-26(34)29-13-4-9-23-17-28-19-32-23/h1-3,6-8,10-12,16-17,19H,4-5,9,13-15,18H2,(H,28,32)(H2,29,30,34)
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 16n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068044
PNG
(2N-(4-bromobenzyl)-2N-(3-{1-[3-(1H-4-imidazolyl)pr...)
Show SMILES CS(NCCCN(Cc1ccc(Br)cc1)c1ccccn1)=NCCCc1cnc[nH]1 |w:21.23|
Show InChI InChI=1S/C22H29BrN6S/c1-30(27-13-4-6-21-16-24-18-26-21)28-14-5-15-29(22-7-2-3-12-25-22)17-19-8-10-20(23)11-9-19/h2-3,7-12,16,18H,4-6,13-15,17H2,1H3,(H,24,26)(H,27,28)
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 50n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068066
PNG
(1-{4-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H27BrCl2N6S/c24-18-6-8-22(30-13-18)32(15-17-5-7-20(25)21(26)12-17)11-2-1-9-28-23(33)29-10-3-4-19-14-27-16-31-19/h5-8,12-14,16H,1-4,9-11,15H2,(H,27,31)(H2,28,29,33)
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 53n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068072
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C21H23BrCl2N6S/c22-16-4-6-20(28-11-16)30(13-15-3-5-18(23)19(24)10-15)9-8-27-21(31)26-7-1-2-17-12-25-14-29-17/h3-6,10-12,14H,1-2,7-9,13H2,(H,25,29)(H2,26,27,31)
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 70n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068040
PNG
(1-{4-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)NCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H25BrCl2N6S/c23-17-4-6-21(29-12-17)31(14-16-3-5-19(24)20(25)11-16)10-2-1-8-27-22(32)28-9-7-18-13-26-15-30-18/h3-6,11-13,15H,1-2,7-10,14H2,(H,26,30)(H2,27,28,32)
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 96n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068056
PNG
(1-{3-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-propyl}...)
Show SMILES Brc1ccc(CN(CCCNC(=S)NCCCNc2ccccn2)c2ccccn2)cc1
Show InChI InChI=1S/C24H29BrN6S/c25-21-11-9-20(10-12-21)19-31(23-8-2-4-14-28-23)18-6-17-30-24(32)29-16-5-15-27-22-7-1-3-13-26-22/h1-4,7-14H,5-6,15-19H2,(H,26,27)(H2,29,30,32)
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 113n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068055
PNG
(1-{3-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-propyl}...)
Show SMILES Brc1ccc(CN(CCCNC(=S)NCCCc2cnc[nH]2)c2ccccn2)cc1
Show InChI InChI=1S/C22H27BrN6S/c23-19-9-7-18(8-10-19)16-29(21-6-1-2-11-25-21)14-4-13-27-22(30)26-12-3-5-20-15-24-17-28-20/h1-2,6-11,15,17H,3-5,12-14,16H2,(H,24,28)(H2,26,27,30)
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 118n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068045
PNG
(1-{5-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C24H29BrCl2N6S/c25-19-7-9-23(31-14-19)33(16-18-6-8-21(26)22(27)13-18)12-3-1-2-10-29-24(34)30-11-4-5-20-15-28-17-32-20/h6-9,13-15,17H,1-5,10-12,16H2,(H,28,32)(H2,29,30,34)
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 132n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068059
PNG
(1-{2-[(3,4-Dichloro-benzyl)-(5-nitro-pyridin-2-yl)...)
Show SMILES [O-][N+](=O)c1ccc(nc1)N(CC[N-]C(=[SH+])NCCCc1cnc[nH]1)Cc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H23Cl2N7O2S/c22-18-5-3-15(10-19(18)23)13-29(20-6-4-17(12-27-20)30(31)32)9-8-26-21(33)25-7-1-2-16-11-24-14-28-16/h3-6,10-12,14H,1-2,7-9,13H2,(H3,24,25,26,28,33)
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 176n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068058
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCNc2ccccn2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C24H27BrCl2N6S/c25-19-7-9-23(32-16-19)33(17-18-6-8-20(26)21(27)15-18)14-4-13-31-24(34)30-12-3-11-29-22-5-1-2-10-28-22/h1-2,5-10,15-16H,3-4,11-14,17H2,(H,28,29)(H2,30,31,34)
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 185n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068072
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C21H23BrCl2N6S/c22-16-4-6-20(28-11-16)30(13-15-3-5-18(23)19(24)10-15)9-8-27-21(31)26-7-1-2-17-12-25-14-29-17/h3-6,10-12,14H,1-2,7-9,13H2,(H,25,29)(H2,26,27,31)
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 310n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068060
PNG
(4-(1H-Imidazol-4-yl)-piperidine-1-carbothioic acid...)
Show SMILES Clc1ccc(CN(CCNC(=S)N2CCC(CC2)c2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H25BrCl2N6S/c24-18-2-4-22(29-12-18)32(14-16-1-3-19(25)20(26)11-16)10-7-28-23(33)31-8-5-17(6-9-31)21-13-27-15-30-21/h1-4,11-13,15,17H,5-10,14H2,(H,27,30)(H,28,33)
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 413n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068042
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=S)NCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C20H21BrCl2N6S/c21-15-2-4-19(27-10-15)29(12-14-1-3-17(22)18(23)9-14)8-7-26-20(30)25-6-5-16-11-24-13-28-16/h1-4,9-11,13H,5-8,12H2,(H,24,28)(H2,25,26,30)
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 476n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068064
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=S)NCCCN2CCCC2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H28BrCl2N5S/c23-18-5-7-21(28-15-18)30(16-17-4-6-19(24)20(25)14-17)13-9-27-22(31)26-8-3-12-29-10-1-2-11-29/h4-7,14-15H,1-3,8-13,16H2,(H2,26,27,31)
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 477n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068059
PNG
(1-{2-[(3,4-Dichloro-benzyl)-(5-nitro-pyridin-2-yl)...)
Show SMILES [O-][N+](=O)c1ccc(nc1)N(CC[N-]C(=[SH+])NCCCc1cnc[nH]1)Cc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H23Cl2N7O2S/c22-18-5-3-15(10-19(18)23)13-29(20-6-4-17(12-27-20)30(31)32)9-8-26-21(33)25-7-1-2-16-11-24-14-28-16/h3-6,10-12,14H,1-2,7-9,13H2,(H3,24,25,26,28,33)
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 500n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068049
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCN2CCCC2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H30BrCl2N5S/c24-19-6-8-22(29-16-19)31(17-18-5-7-20(25)21(26)15-18)14-4-10-28-23(32)27-9-3-13-30-11-1-2-12-30/h5-8,15-16H,1-4,9-14,17H2,(H2,27,28,32)
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 514n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068047
PNG
(1-{4-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)Nc2cccc(c2)-c2c[nH]cn2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C26H25BrCl2N6S/c27-20-7-9-25(32-14-20)35(16-18-6-8-22(28)23(29)12-18)11-2-1-10-31-26(36)34-21-5-3-4-19(13-21)24-15-30-17-33-24/h3-9,12-15,17H,1-2,10-11,16H2,(H,30,33)(H2,31,34,36)
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 520n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068066
PNG
(1-{4-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H27BrCl2N6S/c24-18-6-8-22(30-13-18)32(15-17-5-7-20(25)21(26)12-17)11-2-1-9-28-23(33)29-10-3-4-19-14-27-16-31-19/h5-8,12-14,16H,1-4,9-11,15H2,(H,27,31)(H2,28,29,33)
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 565n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068039
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H25BrCl2N6S/c23-17-5-7-21(29-12-17)31(14-16-4-6-19(24)20(25)11-16)10-2-9-28-22(32)27-8-1-3-18-13-26-15-30-18/h4-7,11-13,15H,1-3,8-10,14H2,(H,26,30)(H2,27,28,32)
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 621n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068045
PNG
(1-{5-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C24H29BrCl2N6S/c25-19-7-9-23(31-14-19)33(16-18-6-8-21(26)22(27)13-18)12-3-1-2-10-29-24(34)30-11-4-5-20-15-28-17-32-20/h6-9,13-15,17H,1-5,10-12,16H2,(H,28,32)(H2,29,30,34)
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 777n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068067
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-naphthalen-1-ylmethyl...)
Show SMILES Brc1ccc(nc1)N(CCCNC(=S)NCCCc1cnc[nH]1)Cc1cccc2ccccc12
Show InChI InChI=1S/C26H29BrN6S/c27-22-11-12-25(31-16-22)33(18-21-8-3-7-20-6-1-2-10-24(20)21)15-5-14-30-26(34)29-13-4-9-23-17-28-19-32-23/h1-3,6-8,10-12,16-17,19H,4-5,9,13-15,18H2,(H,28,32)(H2,29,30,34)
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 778n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068062
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES CN(C)CCCNC(=S)NCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1
Show InChI InChI=1S/C20H26BrCl2N5S/c1-27(2)10-3-8-24-20(29)25-9-11-28(19-7-5-16(21)13-26-19)14-15-4-6-17(22)18(23)12-15/h4-7,12-13H,3,8-11,14H2,1-2H3,(H2,24,25,29)
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 803n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068053
PNG
(1-(4-Amino-butyl)-3-{3-[(5-bromo-pyridin-2-yl)-(3,...)
Show SMILES NCCCCNC(=S)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1
Show InChI InChI=1S/C20H26BrCl2N5S/c21-16-5-7-19(27-13-16)28(14-15-4-6-17(22)18(23)12-15)11-3-10-26-20(29)25-9-2-1-8-24/h4-7,12-13H,1-3,8-11,14,24H2,(H2,25,26,29)
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 830n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068042
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=S)NCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C20H21BrCl2N6S/c21-15-2-4-19(27-10-15)29(12-14-1-3-17(22)18(23)9-14)8-7-26-20(30)25-6-5-16-11-24-13-28-16/h1-4,9-11,13H,5-8,12H2,(H,24,28)(H2,25,26,30)
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 894n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068069
PNG
(1-(4-Amino-butyl)-3-{3-[(5-bromo-pyridin-2-yl)-nap...)
Show SMILES NCCCCNC(=S)NCCCN(Cc1cccc2ccccc12)c1ccc(Br)cn1
Show InChI InChI=1S/C24H30BrN5S/c25-21-11-12-23(29-17-21)30(16-6-15-28-24(31)27-14-4-3-13-26)18-20-9-5-8-19-7-1-2-10-22(19)20/h1-2,5,7-12,17H,3-4,6,13-16,18,26H2,(H2,27,28,31)
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 1.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068053
PNG
(1-(4-Amino-butyl)-3-{3-[(5-bromo-pyridin-2-yl)-(3,...)
Show SMILES NCCCCNC(=S)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1
Show InChI InChI=1S/C20H26BrCl2N5S/c21-16-5-7-19(27-13-16)28(14-15-4-6-17(22)18(23)12-15)11-3-10-26-20(29)25-9-2-1-8-24/h4-7,12-13H,1-3,8-11,14,24H2,(H2,25,26,29)
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 1.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068060
PNG
(4-(1H-Imidazol-4-yl)-piperidine-1-carbothioic acid...)
Show SMILES Clc1ccc(CN(CCNC(=S)N2CCC(CC2)c2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H25BrCl2N6S/c24-18-2-4-22(29-12-18)32(14-16-1-3-19(25)20(26)11-16)10-7-28-23(33)31-8-5-17(6-9-31)21-13-27-15-30-21/h1-4,11-13,15,17H,5-10,14H2,(H,27,30)(H,28,33)
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 1.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068052
PNG
(1-(1H-Benzotriazol-5-yl)-3-{2-[(5-bromo-pyridin-2-...)
Show SMILES Clc1ccc(CN(CCNC(=S)Nc2ccc3nn[nH]c3c2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C21H18BrCl2N7S/c22-14-2-6-20(26-11-14)31(12-13-1-4-16(23)17(24)9-13)8-7-25-21(32)27-15-3-5-18-19(10-15)29-30-28-18/h1-6,9-11H,7-8,12H2,(H2,25,27,32)(H,28,29,30)
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 1.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068051
PNG
(1-(1H-Benzoimidazol-2-ylmethyl)-3-{2-[(5-bromo-pyr...)
Show SMILES Clc1ccc(CN(CCNC(=S)NCc2nc3ccccc3[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H21BrCl2N6S/c24-16-6-8-22(28-12-16)32(14-15-5-7-17(25)18(26)11-15)10-9-27-23(33)29-13-21-30-19-3-1-2-4-20(19)31-21/h1-8,11-12H,9-10,13-14H2,(H,30,31)(H2,27,29,33)
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 1.20E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068050
PNG
(1-{4-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)NCCCn2ccnc2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H27BrCl2N6S/c24-19-5-7-22(30-15-19)32(16-18-4-6-20(25)21(26)14-18)12-2-1-8-28-23(33)29-9-3-11-31-13-10-27-17-31/h4-7,10,13-15,17H,1-3,8-9,11-12,16H2,(H2,28,29,33)
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 1.40E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068049
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCN2CCCC2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H30BrCl2N5S/c24-19-6-8-22(29-16-19)31(17-18-5-7-20(25)21(26)15-18)14-4-10-28-23(32)27-9-3-13-30-11-1-2-12-30/h5-8,15-16H,1-4,9-14,17H2,(H2,27,28,32)
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 1.60E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068064
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=S)NCCCN2CCCC2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H28BrCl2N5S/c23-18-5-7-21(28-15-18)30(16-17-4-6-19(24)20(25)14-17)13-9-27-22(31)26-8-3-12-29-10-1-2-11-29/h4-7,14-15H,1-3,8-13,16H2,(H2,26,27,31)
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 1.70E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068057
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCc2ccccn2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H24BrCl2N5S/c24-18-6-8-22(30-15-18)31(16-17-5-7-20(25)21(26)14-17)13-3-11-28-23(32)29-12-9-19-4-1-2-10-27-19/h1-2,4-8,10,14-15H,3,9,11-13,16H2,(H2,28,29,32)
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 1.70E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068047
PNG
(1-{4-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)Nc2cccc(c2)-c2c[nH]cn2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C26H25BrCl2N6S/c27-20-7-9-25(32-14-20)35(16-18-6-8-22(28)23(29)12-18)11-2-1-10-31-26(36)34-21-5-3-4-19(13-21)24-15-30-17-33-24/h3-9,12-15,17H,1-2,10-11,16H2,(H,30,33)(H2,31,34,36)
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 1.70E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068061
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCn2ccnc2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H25BrCl2N6S/c23-18-4-6-21(29-14-18)31(15-17-3-5-19(24)20(25)13-17)11-2-8-28-22(32)27-7-1-10-30-12-9-26-16-30/h3-6,9,12-14,16H,1-2,7-8,10-11,15H2,(H2,27,28,32)
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 1.70E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50272772
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 |r|
Show InChI InChI=1S/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29-,34-,36+,37+,38-,39-,40+,41+,42+/m1/s1
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 1.90E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068069
PNG
(1-(4-Amino-butyl)-3-{3-[(5-bromo-pyridin-2-yl)-nap...)
Show SMILES NCCCCNC(=S)NCCCN(Cc1cccc2ccccc12)c1ccc(Br)cn1
Show InChI InChI=1S/C24H30BrN5S/c25-21-11-12-23(29-17-21)30(16-6-15-28-24(31)27-14-4-3-13-26)18-20-9-5-8-19-7-1-2-10-22(19)20/h1-2,5,7-12,17H,3-4,6,13-16,18,26H2,(H2,27,28,31)
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 2.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068040
PNG
(1-{4-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)NCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H25BrCl2N6S/c23-17-4-6-21(29-12-17)31(14-16-3-5-19(24)20(25)11-16)10-2-1-8-27-22(32)28-9-7-18-13-26-15-30-18/h3-6,11-13,15H,1-2,7-10,14H2,(H,26,30)(H2,27,28,32)
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 2.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068050
PNG
(1-{4-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)NCCCn2ccnc2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H27BrCl2N6S/c24-19-5-7-22(30-15-19)32(16-18-4-6-20(25)21(26)14-18)12-2-1-8-28-23(33)29-9-3-11-31-13-10-27-17-31/h4-7,10,13-15,17H,1-3,8-9,11-12,16H2,(H2,28,29,33)
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 2.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068062
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES CN(C)CCCNC(=S)NCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1
Show InChI InChI=1S/C20H26BrCl2N5S/c1-27(2)10-3-8-24-20(29)25-9-11-28(19-7-5-16(21)13-26-19)14-15-4-6-17(22)18(23)12-15/h4-7,12-13H,3,8-11,14H2,1-2H3,(H2,24,25,29)
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 2.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068061
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCn2ccnc2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H25BrCl2N6S/c23-18-4-6-21(29-14-18)31(15-17-3-5-19(24)20(25)13-17)11-2-8-28-22(32)27-7-1-10-30-12-9-26-16-30/h3-6,9,12-14,16H,1-2,7-8,10-11,15H2,(H2,27,28,32)
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 2.20E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068065
PNG
(1-(3-Amino-propyl)-3-{2-[(5-bromo-pyridin-2-yl)-(3...)
Show SMILES NCCCNC(=S)NCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1
Show InChI InChI=1S/C18H22BrCl2N5S/c19-14-3-5-17(25-11-14)26(9-8-24-18(27)23-7-1-6-22)12-13-2-4-15(20)16(21)10-13/h2-5,10-11H,1,6-9,12,22H2,(H2,23,24,27)
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 2.30E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068055
PNG
(1-{3-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-propyl}...)
Show SMILES Brc1ccc(CN(CCCNC(=S)NCCCc2cnc[nH]2)c2ccccn2)cc1
Show InChI InChI=1S/C22H27BrN6S/c23-19-9-7-18(8-10-19)16-29(21-6-1-2-11-25-21)14-4-13-27-22(30)26-12-3-5-20-15-24-17-28-20/h1-2,6-11,15,17H,3-5,12-14,16H2,(H,24,28)(H2,26,27,30)
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 2.50E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068052
PNG
(1-(1H-Benzotriazol-5-yl)-3-{2-[(5-bromo-pyridin-2-...)
Show SMILES Clc1ccc(CN(CCNC(=S)Nc2ccc3nn[nH]c3c2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C21H18BrCl2N7S/c22-14-2-6-20(26-11-14)31(12-13-1-4-16(23)17(24)9-13)8-7-25-21(32)27-15-3-5-18-19(10-15)29-30-28-18/h1-6,9-11H,7-8,12H2,(H2,25,27,32)(H,28,29,30)
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 3.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068063
PNG
((12S,15R,18S)-9-(4-Amino-butyl)-3-benzyl-15-(4-hyd...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O
Show InChI InChI=1S/C44H56N8O7/c1-26(2)38-43(58)50-37(23-28-12-6-5-7-13-28)44(59)52(4)27(3)39(54)48-35(22-29-17-19-31(53)20-18-29)41(56)49-36(24-30-25-46-33-15-9-8-14-32(30)33)42(57)47-34(40(55)51-38)16-10-11-21-45/h5-9,12-15,17-20,25-27,34-38,46,53H,10-11,16,21-24,45H2,1-4H3,(H,47,57)(H,48,54)(H,49,56)(H,50,58)(H,51,55)/t27-,34-,35+,36-,37-,38-/m0/s1
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 3.20E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068046
PNG
(1-{4-[(3,4-Dichloro-benzyl)-pyridin-2-yl-amino]-bu...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)NCCCn2ccnc2)c2ccccn2)cc1Cl
Show InChI InChI=1S/C23H28Cl2N6S/c24-20-8-7-19(16-21(20)25)17-31(22-6-1-2-9-27-22)14-4-3-10-28-23(32)29-11-5-13-30-15-12-26-18-30/h1-2,6-9,12,15-16,18H,3-5,10-11,13-14,17H2,(H2,28,29,32)
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 4.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068065
PNG
(1-(3-Amino-propyl)-3-{2-[(5-bromo-pyridin-2-yl)-(3...)
Show SMILES NCCCNC(=S)NCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1
Show InChI InChI=1S/C18H22BrCl2N5S/c19-14-3-5-17(25-11-14)26(9-8-24-18(27)23-7-1-6-22)12-13-2-4-15(20)16(21)10-13/h2-5,10-11H,1,6-9,12,22H2,(H2,23,24,27)
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 4.20E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068043
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=O)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C21H23BrCl2N6O/c22-16-4-6-20(28-11-16)30(13-15-3-5-18(23)19(24)10-15)9-8-27-21(31)26-7-1-2-17-12-25-14-29-17/h3-6,10-12,14H,1-2,7-9,13H2,(H,25,29)(H2,26,27,31)
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 4.20E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068044
PNG
(2N-(4-bromobenzyl)-2N-(3-{1-[3-(1H-4-imidazolyl)pr...)
Show SMILES CS(NCCCN(Cc1ccc(Br)cc1)c1ccccn1)=NCCCc1cnc[nH]1 |w:21.23|
Show InChI InChI=1S/C22H29BrN6S/c1-30(27-13-4-6-21-16-24-18-26-21)28-14-5-15-29(22-7-2-3-12-25-22)17-19-8-10-20(23)11-9-19/h2-3,7-12,16,18H,4-6,13-15,17H2,1H3,(H,24,26)(H,27,28)
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 4.60E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068070
PNG
(1-{3-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-propyl}...)
Show SMILES Brc1ccc(CN(CCCNC(=S)NCCCn2ccnc2)c2ccccn2)cc1
Show InChI InChI=1S/C22H27BrN6S/c23-20-8-6-19(7-9-20)17-29(21-5-1-2-10-25-21)15-4-12-27-22(30)26-11-3-14-28-16-13-24-18-28/h1-2,5-10,13,16,18H,3-4,11-12,14-15,17H2,(H2,26,27,30)
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 7.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068054
PNG
(1-{4-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-butyl}-...)
Show SMILES Brc1ccc(CN(CCCCNC(=S)NCCCn2ccnc2)c2ccccn2)cc1
Show InChI InChI=1S/C23H29BrN6S/c24-21-9-7-20(8-10-21)18-30(22-6-1-2-11-26-22)16-4-3-12-27-23(31)28-13-5-15-29-17-14-25-19-29/h1-2,6-11,14,17,19H,3-5,12-13,15-16,18H2,(H2,27,28,31)
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 7.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068046
PNG
(1-{4-[(3,4-Dichloro-benzyl)-pyridin-2-yl-amino]-bu...)
Show SMILES Clc1ccc(CN(CCCCNC(=S)NCCCn2ccnc2)c2ccccn2)cc1Cl
Show InChI InChI=1S/C23H28Cl2N6S/c24-20-8-7-19(16-21(20)25)17-31(22-6-1-2-9-27-22)14-4-3-10-28-23(32)29-11-5-13-30-15-12-26-18-30/h1-2,6-9,12,15-16,18H,3-5,10-11,13-14,17H2,(H2,28,29,32)
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 8.00E+3n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068054
PNG
(1-{4-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-butyl}-...)
Show SMILES Brc1ccc(CN(CCCCNC(=S)NCCCn2ccnc2)c2ccccn2)cc1
Show InChI InChI=1S/C23H29BrN6S/c24-21-9-7-20(8-10-21)18-30(22-6-1-2-11-26-22)16-4-3-12-27-23(31)28-13-5-15-29-17-14-25-19-29/h1-2,6-11,14,17,19H,3-5,12-13,15-16,18H2,(H2,27,28,31)
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 1.20E+4n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at sst2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068041
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=S)Nc2ccc(cc2)N2CCCCC2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C26H28BrCl2N5S/c27-20-5-11-25(31-17-20)34(18-19-4-10-23(28)24(29)16-19)15-12-30-26(35)32-21-6-8-22(9-7-21)33-13-2-1-3-14-33/h4-11,16-17H,1-3,12-15,18H2,(H2,30,32,35)
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 1.50E+4n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068070
PNG
(1-{3-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-propyl}...)
Show SMILES Brc1ccc(CN(CCCNC(=S)NCCCn2ccnc2)c2ccccn2)cc1
Show InChI InChI=1S/C22H27BrN6S/c23-20-8-6-19(7-9-20)17-29(21-5-1-2-10-25-21)15-4-12-27-22(30)26-11-3-14-28-16-13-24-18-28/h1-2,5-10,13,16,18H,3-4,11-12,14-15,17H2,(H2,26,27,30)
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 3.30E+4n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068038
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)Nc2ccc(cc2)N2CCCCC2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C27H30BrCl2N5S/c28-21-6-12-26(32-18-21)35(19-20-5-11-24(29)25(30)17-20)16-4-13-31-27(36)33-22-7-9-23(10-8-22)34-14-2-1-3-15-34/h5-12,17-18H,1-4,13-16,19H2,(H2,31,33,36)
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 7.10E+4n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50068048
PNG
(1-{4-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-butyl}-...)
Show SMILES Brc1ccc(CN(CCCCNC(=S)NCCCc2ccccc2)c2ccccn2)cc1
Show InChI InChI=1S/C26H31BrN4S/c27-24-15-13-23(14-16-24)21-31(25-12-4-5-17-28-25)20-7-6-18-29-26(32)30-19-8-11-22-9-2-1-3-10-22/h1-5,9-10,12-17H,6-8,11,18-21H2,(H2,29,30,32)
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 7.10E+4n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068057
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCc2ccccn2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H24BrCl2N5S/c24-18-6-8-22(30-15-18)31(16-17-5-7-20(25)21(26)14-17)13-3-11-28-23(32)29-12-9-19-4-1-2-10-27-19/h1-2,4-8,10,14-15H,3,9,11-13,16H2,(H2,28,29,32)
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 7.40E+4n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068056
PNG
(1-{3-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-propyl}...)
Show SMILES Brc1ccc(CN(CCCNC(=S)NCCCNc2ccccn2)c2ccccn2)cc1
Show InChI InChI=1S/C24H29BrN6S/c25-21-11-9-20(10-12-21)19-31(23-8-2-4-14-28-23)18-6-17-30-24(32)29-16-5-15-27-22-7-1-3-13-26-22/h1-4,7-14H,5-6,15-19H2,(H,26,27)(H2,29,30,32)
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 1.14E+5n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068038
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)Nc2ccc(cc2)N2CCCCC2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C27H30BrCl2N5S/c28-21-6-12-26(32-18-21)35(19-20-5-11-24(29)25(30)17-20)16-4-13-31-27(36)33-22-7-9-23(10-8-22)34-14-2-1-3-15-34/h5-12,17-18H,1-4,13-16,19H2,(H2,31,33,36)
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>3.00E+5n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068051
PNG
(1-(1H-Benzoimidazol-2-ylmethyl)-3-{2-[(5-bromo-pyr...)
Show SMILES Clc1ccc(CN(CCNC(=S)NCc2nc3ccccc3[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C23H21BrCl2N6S/c24-16-6-8-22(28-12-16)32(14-15-5-7-17(25)18(26)11-15)10-9-27-23(33)29-13-21-30-19-3-1-2-4-20(19)31-21/h1-8,11-12H,9-10,13-14H2,(H,30,31)(H2,27,29,33)
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>3.00E+5n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068058
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCNc2ccccn2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C24H27BrCl2N6S/c25-19-7-9-23(32-16-19)33(17-18-6-8-20(26)21(27)15-18)14-4-13-31-24(34)30-12-3-11-29-22-5-1-2-10-28-22/h1-2,5-10,15-16H,3-4,11-14,17H2,(H,28,29)(H2,30,31,34)
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>3.00E+5n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068048
PNG
(1-{4-[(4-Bromo-benzyl)-pyridin-2-yl-amino]-butyl}-...)
Show SMILES Brc1ccc(CN(CCCCNC(=S)NCCCc2ccccc2)c2ccccn2)cc1
Show InChI InChI=1S/C26H31BrN4S/c27-24-15-13-23(14-16-24)21-31(25-12-4-5-17-28-25)20-7-6-18-29-26(32)30-19-8-11-22-9-2-1-3-10-22/h1-5,9-10,12-17H,6-8,11,18-21H2,(H2,29,30,32)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
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>3.00E+5n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50068041
PNG
(1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCNC(=S)Nc2ccc(cc2)N2CCCCC2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C26H28BrCl2N5S/c27-20-5-11-25(31-17-20)34(18-19-4-10-23(28)24(29)16-19)15-12-30-26(35)32-21-6-8-22(9-7-21)33-13-2-1-3-14-33/h4-11,16-17H,1-3,12-15,18H2,(H2,30,32,35)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Similars
Article
PubMed
>3.00E+5n/an/an/an/an/an/an/an/a



Northeast Louisiana University

Curated by ChEMBL


Assay Description
In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligand

J Med Chem 41: 4693-705 (1998)


Article DOI: 10.1021/jm980118e
BindingDB Entry DOI: 10.7270/Q2TT4RNG
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%