Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutrophil elastase (Homo sapiens (Human)) | BDBM50068279 (CHEMBL359047 | {(S)-1-[(S)-1-((R)-2-{(S)-1-[(S)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Institut Jacques Monod (UMR CNRS 7592/Universités Paris VI and VII) Curated by ChEMBL | Assay Description Inhibition constant of compound measured toward human leukocyte elastase (HLE) at pH 8 and 25 degree C. | J Med Chem 41: 4833-43 (1998) Article DOI: 10.1021/jm980419o BindingDB Entry DOI: 10.7270/Q25D8R0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50068278 (((S)-1-{(S)-2-[(R)-2-(N'-{(S)-1-[(S)-1-((S)-1-Isop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Institut Jacques Monod (UMR CNRS 7592/Universités Paris VI and VII) Curated by ChEMBL | Assay Description Inhibition constant of compound measured toward human leukocyte elastase (HLE) at pH 8 and 25 degree C. | J Med Chem 41: 4833-43 (1998) Article DOI: 10.1021/jm980419o BindingDB Entry DOI: 10.7270/Q25D8R0F | |||||||||||
More data for this Ligand-Target Pair |