Affinity Data by PubMed id=9871678

PubMed code 9871678

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thermolysin (Bacillus thermoproteolyticus)	BDBM50025915 (CHEMBL16622 \| [2-Benzyl-3-(formyl-hydroxy-amino)-p...) Show SMILES ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50069976 ((3Z)-2-benzyl-3-[benzyl(oxido)imino]propanamide \| ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50069975 (({(3Z)-2-benzyl-3-[benzyl(oxido)imino]propanoyl}am...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50069977 (CHEMBL325732 \| methyl (3Z)-2-benzyl-3-[benzyl(oxid...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50069978 (CHEMBL111741 \| methyl 2-benzyl-3-[(Z)-benzylidene(...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.44E+5	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50025924 (3-Benzyl-N-carboxymethyl-succinamic acid \| CHEMBL1...) Show SMILES OC(=O)CNC(=O)C(CC(O)=O)Cc1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50069980 (2-[(Z)-benzylidene(oxido)amino]-3-phenylpropanamid...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	7.74E+5	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50069979 (CHEMBL110107 \| methyl 2-[(Z)-benzylidene(oxido)ami...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.91E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%