Affinity Data by PubMed id=9873370

PubMed code 9873370

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50070471 (6-(3,5-Dimethyl-benzyl)-5-isopropyl-2-methylsulfan...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Compound was evaluated for enzymatic inhibitory activity against recombinant HIV reverse transcriptase				Bioorg Med Chem Lett 8: 1461-6 (1999) BindingDB Entry DOI: 10.7270/Q24X56XN
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50070469 (6-Benzyl-5-isopropyl-2-methylsulfanylmethylsulfany...) Show SMILES CSCSc1nc(Cc2ccccc2)c(C(C)C)c(=O)[nH]1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Compound was evaluated for enzymatic inhibitory activity against recombinant HIV reverse transcriptase				Bioorg Med Chem Lett 8: 1461-6 (1999) BindingDB Entry DOI: 10.7270/Q24X56XN
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50070468 (6-Benzyl-5-ethyl-2-methylsulfanylmethylsulfanyl-3H...) Show SMILES CCc1c(Cc2ccccc2)nc(SCSC)[nH]c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Compound was evaluated for enzymatic inhibitory activity against recombinant HIV reverse transcriptase				Bioorg Med Chem Lett 8: 1461-6 (1999) BindingDB Entry DOI: 10.7270/Q24X56XN
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50070470 (6-Benzyl-5-methyl-2-methylsulfanylmethylsulfanyl-3...) Show SMILES CSCSc1nc(Cc2ccccc2)c(C)c(=O)[nH]1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Compound was evaluated for enzymatic inhibitory activity against recombinant HIV reverse transcriptase				Bioorg Med Chem Lett 8: 1461-6 (1999) BindingDB Entry DOI: 10.7270/Q24X56XN
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50002692 ((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Compound was evaluated for enzymatic inhibitory activity against recombinant HIV reverse transcriptase				Bioorg Med Chem Lett 8: 1461-6 (1999) BindingDB Entry DOI: 10.7270/Q24X56XN
Institute Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%