Affinity Data by PubMed id=9873462

PubMed code 9873462

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Substance-K receptor (Homo sapiens (Human))	BDBM50403654 (CHEMBL2115073) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071118 (CHEMBL2111522 \| CHEMBL443264 \| N-[2-(3,4-Dichloro-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071112 (CHEMBL56835 \| N-[4-(4-Acetylamino-4-phenyl-piperid...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071112 (CHEMBL56835 \| N-[4-(4-Acetylamino-4-phenyl-piperid...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50216091 (CHEMBL2111522) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071118 (CHEMBL2111522 \| CHEMBL443264 \| N-[2-(3,4-Dichloro-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071125 (CHEMBL56481 \| N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-e...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071120 (CHEMBL56788 \| N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-h...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071119 (CHEMBL56143 \| N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-h...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071115 (CHEMBL58638 \| N-[2-(3,4-Dichloro-phenyl)-4-(4-{1-[...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071121 (CHEMBL301437 \| N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071122 (CHEMBL417940 \| N-[2-(3,4-Dichloro-phenyl)-4-(4-pro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071126 (CHEMBL59542 \| N-[2-(3,4-Dichloro-phenyl)-4-(4-prop...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071124 (CHEMBL56739 \| N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-h...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071123 (CHEMBL56274 \| N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-h...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071113 (Acetic acid 2-{1-[4-(benzoyl-methyl-amino)-3-(3,4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071117 (CHEMBL292415 \| N-{2-(3,4-Dichloro-phenyl)-4-[4-(2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071116 (CHEMBL58331 \| N-[4-[4-(2-Acetylamino-ethyl)-piperi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071114 (CHEMBL57224 \| N-[2-(3,4-Dichloro-phenyl)-4-(4-hydr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	142	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
ZENECA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%