Affinity Data by PubMed id=9873603

PubMed code 9873603

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50000655 ((4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50071865 ((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50071865 ((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50071864 (10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50000655 ((4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50071865 ((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50071865 ((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50071864 (10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50071865 ((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	222	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50071865 ((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	222	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	679	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000655 ((4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50071864 (10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50071865 ((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.180	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for its ability to stimulate [35S]GTP-gamma-S, binding to membranes from C6 glioma cells stably expressing rat mu opioid receptor				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50071865 ((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.180	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for its ability to stimulate [35S]GTP-gamma-S, binding to membranes from C6 glioma cells stably expressing rat mu opioid receptor...				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for its ability to stimulate [35S]GTP-gamma-S, binding to membranes from C6 glioma cells stably expressing rat mu opioid receptor				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50071864 (10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for its ability to stimulate [35S]GTP-gamma-S, binding to membranes from C6 glioma cells stably expressing rat mu opioid receptor				Bioorg Med Chem Lett 8: 2685-8 (1999) BindingDB Entry DOI: 10.7270/Q2154HJJ
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%