Affinity Data by PubMed id=9873607

PubMed code 9873607

Found 21 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50071948 (CHEMBL314535 \| Urea analogue) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of blood coagulation protein factor Xa				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50071942 (3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of blood coagulation factor X				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50071946 (3-(3-{4-[(Z)-amino(imino)methyl]phenyl}-2-oxo-1,3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of trypsin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50071942 (3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of trypsin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50071941 (3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-tetrahydro-py...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of blood coagulation factor X				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50071946 (3-(3-{4-[(Z)-amino(imino)methyl]phenyl}-2-oxo-1,3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of blood coagulation factor X				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50071948 (CHEMBL314535 \| Urea analogue) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of trypsin				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50071945 (3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of trypsin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50071947 (4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of trypsin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50071942 (3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of thrombin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50071943 (3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-imidazolidin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of blood coagulation factor X				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50071944 (4-[3-(3-Carbamimidoyl-phenyl)-2-oxo-[1,3]diazepan-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of blood coagulation factor X				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50071948 (CHEMBL314535 \| Urea analogue) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of thrombin				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50071945 (3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of blood coagulation factor X				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50071941 (3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-tetrahydro-py...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of thrombin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50071947 (4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of blood coagulation factor X				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50071946 (3-(3-{4-[(Z)-amino(imino)methyl]phenyl}-2-oxo-1,3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of thrombin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50071943 (3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-imidazolidin-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of thrombin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50071944 (4-[3-(3-Carbamimidoyl-phenyl)-2-oxo-[1,3]diazepan-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of thrombin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50071947 (4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of thrombin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50071945 (3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Compound was tested for inhibition of thrombin.				Bioorg Med Chem Lett 8: 2705-10 (1999) BindingDB Entry DOI: 10.7270/Q23R0S13
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%