Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50071958 (Biphenylene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against human Dopamine receptor D3 transfected in CHO cell membranes to stimulate [3H]-thymidine uptake | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50071959 (9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against human Dopamine receptor D3 transfected in CHO cell membranes to stimulate [3H]-thymidine uptake | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50071960 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Affinity of the compound against D4 receptor was evaluated | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50071958 (Biphenylene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against 5-hydroxytryptamine 2 receptor from rat | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50071959 (9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 217 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against Dopamine receptor D2 subtype from primate | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50071959 (9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 223 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against 5-hydroxytryptamine 2 receptor from rat | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50071958 (Biphenylene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 262 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against Dopamine receptor D2 subtype from primate | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50071958 (Biphenylene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 547 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against Alpha-1 adrenergic receptor from rat | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50071959 (9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 642 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against Alpha-1 adrenergic receptor from rat | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50071958 (Biphenylene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against human Dopamine receptor D4 transfected in CHO cell membranes | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50071959 (9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against human Dopamine receptor D4 transfected in CHO cell membranes | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50071958 (Biphenylene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against Dopamine receptor D1 transfected in CHO cell membranes | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50071959 (9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against Dopamine receptor D1 transfected in CHO cell membranes | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50071958 (Biphenylene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against human Dopamine receptor D5 transfected in CHO cell membranes | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50071959 (9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity against human Dopamine receptor D5 transfected in CHO cell membranes | Bioorg Med Chem Lett 8: 2715-8 (1999) BindingDB Entry DOI: 10.7270/Q200018M | |||||||||||
More data for this Ligand-Target Pair |