Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutrophil elastase (Homo sapiens (Human)) | BDBM104821 (US8569314, 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104822 (US8569314, 23) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104826 (US8569314, 56) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104824 (US8569314, 50) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104823 (US8569314, 35) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104825 (US8569314, 53) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104820 (US8569314, 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104828 (US8569314, 78) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104829 (US8569314, 90) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM104827 (US8569314, 67) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido... | US Patent US8569314 (2013) BindingDB Entry DOI: 10.7270/Q2FJ2FF4 | |||||||||||
More data for this Ligand-Target Pair |