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USPatent US8772285

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM126004
PNG
(US8772285, 27)
Show SMILES C(NC1CC1)c1ccc2nc(sc2c1)N1CCN(CC1)C1CC1
Show InChI InChI=1S/C18H24N4S/c1-6-16-17(11-13(1)12-19-14-2-3-14)23-18(20-16)22-9-7-21(8-10-22)15-4-5-15/h1,6,11,14-15,19H,2-5,7-10,12H2
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Similars

US Patent
0.900n/an/an/an/an/an/an/an/a



High Point Pharmaceuticals, LLC

US Patent


Assay Description
The ability of the compounds to bind and interact with the human H3 receptor as agonists, inverse agonists and/or antagonists, is determined by a fun...


US Patent US8772285 (2014)


BindingDB Entry DOI: 10.7270/Q2P849KF
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM126003
PNG
(US8772285, 17)
Show SMILES C(N1CCCC1)c1ccc2nc(sc2c1)N1CCN(CC1)C1CC1
Show InChI InChI=1S/C19H26N4S/c1-2-8-21(7-1)14-15-3-6-17-18(13-15)24-19(20-17)23-11-9-22(10-12-23)16-4-5-16/h3,6,13,16H,1-2,4-5,7-12,14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
1.80n/an/an/an/an/an/an/an/a



High Point Pharmaceuticals, LLC

US Patent


Assay Description
The ability of the compounds to bind and interact with the human H3 receptor as agonists, inverse agonists and/or antagonists, is determined by a fun...


US Patent US8772285 (2014)


BindingDB Entry DOI: 10.7270/Q2P849KF
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%