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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154612 (US8999957, Column 165-167, Compound 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154863 (US8999957, Table 3, Compound 136) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154864 (US8999957, Table 3, Compound 137) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154874 (US8999957, Table 3, Compound 147) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154600 (US8999957, Column 153, Compound 5 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 7.2 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Activity of compounds against inactive ERK2 was tested in a coupled MEK1/ERK2 IMAP assay as follows: Compounds were diluted to 25x final test concent... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154613 (US8999957, Column 165-167, Compound 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154600 (US8999957, Column 153, Compound 5 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 7.2 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Activity of compounds against inactive ERK2 was tested in a coupled MEK1/ERK2 IMAP assay as follows: Compounds were diluted to 25x final test concent... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154592 (US8999957, Column 143, Compound 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154614 (US8999957, Column 165-167, Compound 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154897 (US8999957, Table 4, Compound 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154900 (US8999957, Table 4, Compound 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.45 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154617 (US8999957, Column 165-167, Compound 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154902 (US8999957, Table 4, Compound 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.59 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154822 (US8999957, Table 3, Compound 94) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154811 (BDBM154818 | US8999957, Table 3, Compound 83) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.41 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154616 (US8999957, Column 165-167, Compound 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154601 (US8999957, Column 155, Compound 1 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154601 (US8999957, Column 155, Compound 1 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154873 (US8999957, Table 3, Compound 146) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154908 (US8999957, Table 4, Compound 13) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.71 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154599 (US8999957, Column 153, Compound 4 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | 7.2 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Activity of compounds against inactive ERK2 was tested in a coupled MEK1/ERK2 IMAP assay as follows: Compounds were diluted to 25x final test concent... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154599 (US8999957, Column 153, Compound 4 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | 7.2 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Activity of compounds against inactive ERK2 was tested in a coupled MEK1/ERK2 IMAP assay as follows: Compounds were diluted to 25x final test concent... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154618 (US8999957, Column 165-167, Compound 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154898 (US8999957, Table 4, Compound 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.09 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154811 (BDBM154818 | US8999957, Table 3, Compound 83) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154909 (US8999957, Table 4, Compound 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.23 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154615 (US8999957, Column 165-167, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154798 (US8999957, Table 3, Compound 70) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.58 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154862 (US8999957, Table 3, Compound 134) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154786 (US8999957, Table 3, Compound 58) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.67 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154904 (US8999957, Table 4, Compound 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.83 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154698 (US8999957, Table 2, Compound 35) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.02 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154622 (US8999957, Column 165-167, Compound 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154745 (US8999957, Table 3, Compound 17 | US8999957, Table...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.46 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154912 (US8999957, Column 328-329, Compund 2 | US8999957, ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154620 (US8999957, Column 165-167, Compound 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154899 (US8999957, Table 4, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154619 (US8999957, Column 165-167, Compound 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154673 (US8999957, Table 2, Compound 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.98 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154751 (US8999957, Table 3, Compound 23) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154600 (US8999957, Column 153, Compound 5 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154600 (US8999957, Column 153, Compound 5 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154837 (US8999957, Table 3, Compound 109) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154599 (US8999957, Column 153, Compound 4 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154599 (US8999957, Column 153, Compound 4 | US8999957, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154624 (US8999957, Column 165-167, Compound 13) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154708 (US8999957, Table 2, Compound 45) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.84 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154710 (US8999957, Table 2, Compound 47) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154755 (US8999957, Table 3, Compound 27) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.46 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM154621 (US8999957, Column 165-167, Compound 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp... | US Patent US8999957 (2015) BindingDB Entry DOI: 10.7270/Q2GB22S9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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