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USPatent US9096595

Compile data set for download or QSAR
Found 51 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173248
PNG
(US9096595, 51)
Show SMILES OC(=O)Cc1c2CCC(Cn2c2cc(Cl)ccc12)N(CC1CC1)c1ncc(F)cn1
Show InChI InChI=1S/C22H22ClFN4O2/c23-14-3-5-17-18(8-21(29)30)19-6-4-16(12-28(19)20(17)7-14)27(11-13-1-2-13)22-25-9-15(24)10-26-22/h3,5,7,9-10,13,16H,1-2,4,6,8,11-12H2,(H,29,30)
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n/an/a 0.600n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173207
PNG
(US9096595, 10)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(F)cc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C22H19F2N3O3/c1-26(22-25-17-8-12(23)3-7-20(17)30-22)14-4-6-18-16(10-21(28)29)15-5-2-13(24)9-19(15)27(18)11-14/h2-3,5,7-9,14H,4,6,10-11H2,1H3,(H,28,29)
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n/an/a 0.700n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173229
PNG
(US9096595, 32)
Show SMILES CN([C@H]1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C19H18ClFN4O2/c1-24(19-22-8-12(21)9-23-19)13-3-5-16-15(7-18(26)27)14-4-2-11(20)6-17(14)25(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,26,27)/t13-/m0/s1
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n/an/a 0.800n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173244
PNG
(US9096595, 47)
Show SMILES COCCN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C21H22ClFN4O3/c1-30-7-6-26(21-24-10-14(23)11-25-21)15-3-5-18-17(9-20(28)29)16-4-2-13(22)8-19(16)27(18)12-15/h2,4,8,10-11,15H,3,5-7,9,12H2,1H3,(H,28,29)
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n/an/a 0.800n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173242
PNG
(US9096595, 45)
Show SMILES CCN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C20H20ClFN4O2/c1-2-25(20-23-9-13(22)10-24-20)14-4-6-17-16(8-19(27)28)15-5-3-12(21)7-18(15)26(17)11-14/h3,5,7,9-10,14H,2,4,6,8,11H2,1H3,(H,27,28)
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n/an/a 1n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173246
PNG
(US9096595, 49)
Show SMILES CCCN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C21H22ClFN4O2/c1-2-7-26(21-24-10-14(23)11-25-21)15-4-6-18-17(9-20(28)29)16-5-3-13(22)8-19(16)27(18)12-15/h3,5,8,10-11,15H,2,4,6-7,9,12H2,1H3,(H,28,29)
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n/an/a 1n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173206
PNG
(US9096595, 9)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(F)cc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C19H18F2N4O2/c1-24(19-22-8-12(21)9-23-19)13-3-5-16-15(7-18(26)27)14-4-2-11(20)6-17(14)25(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,26,27)
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n/an/a 1n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173247
PNG
(US9096595, 50)
Show SMILES CCN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C23H21ClFN3O3/c1-2-27(23-26-18-10-14(25)4-8-21(18)31-23)15-5-7-19-17(11-22(29)30)16-6-3-13(24)9-20(16)28(19)12-15/h3-4,6,8-10,15H,2,5,7,11-12H2,1H3,(H,29,30)
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n/an/a 1n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173238
PNG
(US9096595, 41)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc2ccc(F)cc2n1
Show InChI InChI=1S/C23H20ClFN4O2/c1-28(23-26-11-13-2-4-15(25)9-19(13)27-23)16-5-7-20-18(10-22(30)31)17-6-3-14(24)8-21(17)29(20)12-16/h2-4,6,8-9,11,16H,5,7,10,12H2,1H3,(H,30,31)
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n/an/a 1n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173217
PNG
(US9096595, 20)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(F)cc3n2C1)c1nc2ccc(F)cc2o1
Show InChI InChI=1S/C22H19F2N3O3/c1-26(22-25-17-6-3-13(24)9-20(17)30-22)14-4-7-18-16(10-21(28)29)15-5-2-12(23)8-19(15)27(18)11-14/h2-3,5-6,8-9,14H,4,7,10-11H2,1H3,(H,28,29)
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n/an/a 1n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173230
PNG
(US9096595, 33)
Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C19H18ClFN4O2/c1-24(19-22-8-12(21)9-23-19)13-3-5-16-15(7-18(26)27)14-4-2-11(20)6-17(14)25(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,26,27)/t13-/m1/s1
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n/an/a 2n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173245
PNG
(US9096595, 48)
Show SMILES CC(C)CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C25H25ClFN3O3/c1-14(2)12-29(25-28-20-10-16(27)4-8-23(20)33-25)17-5-7-21-19(11-24(31)32)18-6-3-15(26)9-22(18)30(21)13-17/h3-4,6,8-10,14,17H,5,7,11-13H2,1-2H3,(H,31,32)
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n/an/a 2n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173240
PNG
(US9096595, 43)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1cnc2cc(F)ccc2n1
Show InChI InChI=1S/C23H20ClFN4O2/c1-28(22-11-26-19-9-14(25)3-6-18(19)27-22)15-4-7-20-17(10-23(30)31)16-5-2-13(24)8-21(16)29(20)12-15/h2-3,5-6,8-9,11,15H,4,7,10,12H2,1H3,(H,30,31)
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n/an/a 2n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173235
PNG
(US9096595, 38)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc(C)cn1
Show InChI InChI=1S/C20H21ClN4O2/c1-12-9-22-20(23-10-12)24(2)14-4-6-17-16(8-19(26)27)15-5-3-13(21)7-18(15)25(17)11-14/h3,5,7,9-10,14H,4,6,8,11H2,1-2H3,(H,26,27)
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n/an/a 2n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173236
PNG
(US9096595, 39)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc2ccccc2n1
Show InChI InChI=1S/C23H21ClN4O2/c1-27(23-25-12-14-4-2-3-5-19(14)26-23)16-7-9-20-18(11-22(29)30)17-8-6-15(24)10-21(17)28(20)13-16/h2-6,8,10,12,16H,7,9,11,13H2,1H3,(H,29,30)
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n/an/a 3n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173243
PNG
(US9096595, 46)
Show SMILES CC(C)N(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C24H23ClFN3O3/c1-13(2)29(24-27-19-10-15(26)4-8-22(19)32-24)16-5-7-20-18(11-23(30)31)17-6-3-14(25)9-21(17)28(20)12-16/h3-4,6,8-10,13,16H,5,7,11-12H2,1-2H3,(H,30,31)
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n/an/a 3n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173241
PNG
(US9096595, 44)
Show SMILES OC(=O)Cc1c2CCC(Cn2c2cc(Cl)ccc12)N(CC(F)F)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C23H19ClF3N3O3/c24-12-1-4-15-16(9-22(31)32)18-5-3-14(10-30(18)19(15)7-12)29(11-21(26)27)23-28-17-8-13(25)2-6-20(17)33-23/h1-2,4,6-8,14,21H,3,5,9-11H2,(H,31,32)
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n/an/a 3n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173214
PNG
(US9096595, 17)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(F)cc3n2C1)c1ncc(Cl)cn1
Show InChI InChI=1S/C19H18ClFN4O2/c1-24(19-22-8-11(20)9-23-19)13-3-5-16-15(7-18(26)27)14-4-2-12(21)6-17(14)25(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,26,27)
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n/an/a 4n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173237
PNG
(US9096595, 40)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc2cc(F)ccc2n1
Show InChI InChI=1S/C23H20ClFN4O2/c1-28(23-26-11-13-8-15(25)3-6-19(13)27-23)16-4-7-20-18(10-22(30)31)17-5-2-14(24)9-21(17)29(20)12-16/h2-3,5-6,8-9,11,16H,4,7,10,12H2,1H3,(H,30,31)
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n/an/a 5n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173228
PNG
(US9096595, 31)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C22H19ClFN3O3/c1-26(22-25-17-9-13(24)3-7-20(17)30-22)14-4-6-18-16(10-21(28)29)15-5-2-12(23)8-19(15)27(18)11-14/h2-3,5,7-9,14H,4,6,10-11H2,1H3,(H,28,29)
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n/an/a 5n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173221
PNG
(US9096595, 24)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C(F)(F)F)c1ncc(F)cn1
Show InChI InChI=1S/C20H18F4N4O2/c1-27(19-25-8-12(21)9-26-19)13-3-5-16-15(7-18(29)30)14-4-2-11(20(22,23)24)6-17(14)28(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,29,30)
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n/an/a 5n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173215
PNG
(US9096595, 18)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(F)cc3n2C1)c1ncc(cn1)C(F)(F)F
Show InChI InChI=1S/C20H18F4N4O2/c1-27(19-25-8-11(9-26-19)20(22,23)24)13-3-5-16-15(7-18(29)30)14-4-2-12(21)6-17(14)28(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,29,30)
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n/an/a 6n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173218
PNG
(US9096595, 21)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc(Cl)cn1
Show InChI InChI=1S/C19H18Cl2N4O2/c1-24(19-22-8-12(21)9-23-19)13-3-5-16-15(7-18(26)27)14-4-2-11(20)6-17(14)25(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,26,27)
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n/an/a 7n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173200
PNG
(US9096595, 3)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccccc3n2C1)c1ncc(cn1)C(F)(F)F
Show InChI InChI=1S/C20H19F3N4O2/c1-26(19-24-9-12(10-25-19)20(21,22)23)13-6-7-17-15(8-18(28)29)14-4-2-3-5-16(14)27(17)11-13/h2-5,9-10,13H,6-8,11H2,1H3,(H,28,29)
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n/an/a 8n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173225
PNG
(US9096595, 28)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C(F)(F)F)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C23H19F4N3O3/c1-29(22-28-17-9-13(24)3-7-20(17)33-22)14-4-6-18-16(10-21(31)32)15-5-2-12(23(25,26)27)8-19(15)30(18)11-14/h2-3,5,7-9,14H,4,6,10-11H2,1H3,(H,31,32)
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n/an/a 8n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173201
PNG
(US9096595, 4)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccccc3n2C1)c1nc2ccc(F)cc2s1
Show InChI InChI=1S/C22H20FN3O2S/c1-25(22-24-17-8-6-13(23)10-20(17)29-22)14-7-9-19-16(11-21(27)28)15-4-2-3-5-18(15)26(19)12-14/h2-6,8,10,14H,7,9,11-12H2,1H3,(H,27,28)
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n/an/a 9n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173199
PNG
(US9096595, 2)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccccc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C19H19FN4O2/c1-23(19-21-9-12(20)10-22-19)13-6-7-17-15(8-18(25)26)14-4-2-3-5-16(14)24(17)11-13/h2-5,9-10,13H,6-8,11H2,1H3,(H,25,26)
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n/an/a 9n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173219
PNG
(US9096595, 22)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C(F)(F)F)c1ncc(Cl)cn1
Show InChI InChI=1S/C20H18ClF3N4O2/c1-27(19-25-8-12(21)9-26-19)13-3-5-16-15(7-18(29)30)14-4-2-11(20(22,23)24)6-17(14)28(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,29,30)
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n/an/a 9n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173231
PNG
(US9096595, 34)
Show SMILES OC(=O)Cc1c2CCC(Cn2c2cc(F)ccc12)Nc1ncc(F)cn1
Show InChI InChI=1S/C18H16F2N4O2/c19-10-1-3-13-14(6-17(25)26)15-4-2-12(9-24(15)16(13)5-10)23-18-21-7-11(20)8-22-18/h1,3,5,7-8,12H,2,4,6,9H2,(H,25,26)(H,21,22,23)
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n/an/a 9n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173227
PNG
(US9096595, 30)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C19H18ClFN4O2/c1-24(19-22-8-12(21)9-23-19)13-3-5-16-15(7-18(26)27)14-4-2-11(20)6-17(14)25(16)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,26,27)
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n/an/a 10n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173232
PNG
(US9096595, 35)
Show SMILES OC(=O)Cc1c2CCC(Cn2c2cc(F)ccc12)Nc1nc2cc(F)ccc2o1
Show InChI InChI=1S/C21H17F2N3O3/c22-11-2-6-19-16(7-11)25-21(29-19)24-13-3-5-17-15(9-20(27)28)14-4-1-12(23)8-18(14)26(17)10-13/h1-2,4,6-8,13H,3,5,9-10H2,(H,24,25)(H,27,28)
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n/an/a 11n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173205
PNG
(US9096595, 8)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(F)ccc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C22H19F2N3O3/c1-26(22-25-17-9-13(24)3-7-20(17)30-22)14-4-6-19-16(10-21(28)29)15-8-12(23)2-5-18(15)27(19)11-14/h2-3,5,7-9,14H,4,6,10-11H2,1H3,(H,28,29)
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n/an/a 12n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173223
PNG
(US9096595, 26)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C(F)(F)F)c1nc2ccc(F)cc2s1
Show InChI InChI=1S/C23H19F4N3O2S/c1-29(22-28-17-6-3-13(24)9-20(17)33-22)14-4-7-18-16(10-21(31)32)15-5-2-12(23(25,26)27)8-19(15)30(18)11-14/h2-3,5-6,8-9,14H,4,7,10-11H2,1H3,(H,31,32)
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n/an/a 16n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173202
PNG
(US9096595, 5)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccccc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C22H20FN3O3/c1-25(22-24-17-10-13(23)6-9-20(17)29-22)14-7-8-19-16(11-21(27)28)15-4-2-3-5-18(15)26(19)12-14/h2-6,9-10,14H,7-8,11-12H2,1H3,(H,27,28)
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n/an/a 16n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173204
PNG
(US9096595, 7)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(F)ccc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C19H18F2N4O2/c1-24(19-22-8-12(21)9-23-19)13-3-5-17-15(7-18(26)27)14-6-11(20)2-4-16(14)25(17)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,26,27)
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n/an/a 17n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173213
PNG
(US9096595, 16)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(Cl)ccc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C22H19ClFN3O3/c1-26(22-25-17-9-13(24)3-7-20(17)30-22)14-4-6-19-16(10-21(28)29)15-8-12(23)2-5-18(15)27(19)11-14/h2-3,5,7-9,14H,4,6,10-11H2,1H3,(H,28,29)
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n/an/a 21n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173198
PNG
(US9096595, 1)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccccc3n2C1)c1ncc(Cl)cn1
Show InChI InChI=1S/C19H19ClN4O2/c1-23(19-21-9-12(20)10-22-19)13-6-7-17-15(8-18(25)26)14-4-2-3-5-16(14)24(17)11-13/h2-5,9-10,13H,6-8,11H2,1H3,(H,25,26)
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n/an/a 21n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173234
PNG
(US9096595, 37)
Show SMILES OC(=O)Cc1c2CCC(Cn2c2cc(Cl)ccc12)Nc1ncc(Cl)cn1
Show InChI InChI=1S/C18H16Cl2N4O2/c19-10-1-3-13-14(6-17(25)26)15-4-2-12(9-24(15)16(13)5-10)23-18-21-7-11(20)8-22-18/h1,3,5,7-8,12H,2,4,6,9H2,(H,25,26)(H,21,22,23)
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n/an/a 27n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173211
PNG
(US9096595, 14)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(C)ccc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C23H22FN3O3/c1-13-3-6-19-16(9-13)17(11-22(28)29)20-7-5-15(12-27(19)20)26(2)23-25-18-10-14(24)4-8-21(18)30-23/h3-4,6,8-10,15H,5,7,11-12H2,1-2H3,(H,28,29)
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n/an/a 42n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173216
PNG
(US9096595, 19)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(F)cc3n2C1)c1nc2cc(F)ccc2s1
Show InChI InChI=1S/C22H19F2N3O2S/c1-26(22-25-17-8-12(23)3-7-20(17)30-22)14-4-6-18-16(10-21(28)29)15-5-2-13(24)9-19(15)27(18)11-14/h2-3,5,7-9,14H,4,6,10-11H2,1H3,(H,28,29)
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n/an/a 51n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173233
PNG
(US9096595, 36)
Show SMILES OC(=O)Cc1c2CCC(Cn2c2cc(Cl)ccc12)Nc1ncc(F)cn1
Show InChI InChI=1S/C18H16ClFN4O2/c19-10-1-3-13-14(6-17(25)26)15-4-2-12(9-24(15)16(13)5-10)23-18-21-7-11(20)8-22-18/h1,3,5,7-8,12H,2,4,6,9H2,(H,25,26)(H,21,22,23)
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n/an/a 65n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173239
PNG
(US9096595, 42)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccc(Cl)cc3n2C1)c1nc(C)nc2ccccc12
Show InChI InChI=1S/C24H23ClN4O2/c1-14-26-20-6-4-3-5-18(20)24(27-14)28(2)16-8-10-21-19(12-23(30)31)17-9-7-15(25)11-22(17)29(21)13-16/h3-7,9,11,16H,8,10,12-13H2,1-2H3,(H,30,31)
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n/an/a 71n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173203
PNG
(US9096595, 6)
Show SMILES CN(C1CCc2c(CC(O)=O)c3ccccc3n2C1)c1nc2cc(F)ccc2s1
Show InChI InChI=1S/C22H20FN3O2S/c1-25(22-24-17-10-13(23)6-9-20(17)29-22)14-7-8-19-16(11-21(27)28)15-4-2-3-5-18(15)26(19)12-14/h2-6,9-10,14H,7-8,11-12H2,1H3,(H,27,28)
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n/an/a 92n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173212
PNG
(US9096595, 15)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(Cl)ccc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C19H18ClFN4O2/c1-24(19-22-8-12(21)9-23-19)13-3-5-17-15(7-18(26)27)14-6-11(20)2-4-16(14)25(17)10-13/h2,4,6,8-9,13H,3,5,7,10H2,1H3,(H,26,27)
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n/an/a 136n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173222
PNG
(US9096595, 25)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(OC(F)(F)F)ccc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C20H18F4N4O3/c1-27(19-25-8-11(21)9-26-19)12-2-4-16-15(7-18(29)30)14-6-13(31-20(22,23)24)3-5-17(14)28(16)10-12/h3,5-6,8-9,12H,2,4,7,10H2,1H3,(H,29,30)
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n/an/a 141n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173209
PNG
(US9096595, 12)
Show SMILES COc1ccc2n3CC(CCc3c(CC(O)=O)c2c1)N(C)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C23H22FN3O4/c1-26(23-25-18-9-13(24)3-8-21(18)31-23)14-4-6-19-17(11-22(28)29)16-10-15(30-2)5-7-20(16)27(19)12-14/h3,5,7-10,14H,4,6,11-12H2,1-2H3,(H,28,29)
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n/an/a 231n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173220
PNG
(US9096595, 23)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(OC(F)(F)F)ccc3n2C1)c1ncc(Cl)cn1
Show InChI InChI=1S/C20H18ClF3N4O3/c1-27(19-25-8-11(21)9-26-19)12-2-4-16-15(7-18(29)30)14-6-13(31-20(22,23)24)3-5-17(14)28(16)10-12/h3,5-6,8-9,12H,2,4,7,10H2,1H3,(H,29,30)
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n/an/a 354n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173210
PNG
(US9096595, 13)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(C)ccc3n2C1)c1ncc(F)cn1
Show InChI InChI=1S/C20H21FN4O2/c1-12-3-5-17-15(7-12)16(8-19(26)27)18-6-4-14(11-25(17)18)24(2)20-22-9-13(21)10-23-20/h3,5,7,9-10,14H,4,6,8,11H2,1-2H3,(H,26,27)
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n/an/a 417n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173208
PNG
(US9096595, 11)
Show SMILES COc1ccc2n3CC(CCc3c(CC(O)=O)c2c1)N(C)c1ncc(F)cn1
Show InChI InChI=1S/C20H21FN4O3/c1-24(20-22-9-12(21)10-23-20)13-3-5-17-16(8-19(26)27)15-7-14(28-2)4-6-18(15)25(17)11-13/h4,6-7,9-10,13H,3,5,8,11H2,1-2H3,(H,26,27)
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n/an/a 420n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173224
PNG
(US9096595, 27)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(OC(F)(F)F)ccc3n2C1)c1nc2ccc(F)cc2s1
Show InChI InChI=1S/C23H19F4N3O3S/c1-29(22-28-17-5-2-12(24)8-20(17)34-22)13-3-6-18-16(10-21(31)32)15-9-14(33-23(25,26)27)4-7-19(15)30(18)11-13/h2,4-5,7-9,13H,3,6,10-11H2,1H3,(H,31,32)
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n/an/a 812n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173226
PNG
(US9096595, 29)
Show SMILES CN(C1CCc2c(CC(O)=O)c3cc(OC(F)(F)F)ccc3n2C1)c1nc2cc(F)ccc2o1
Show InChI InChI=1S/C23H19F4N3O4/c1-29(22-28-17-8-12(24)2-7-20(17)33-22)13-3-5-18-16(10-21(31)32)15-9-14(34-23(25,26)27)4-6-19(15)30(18)11-13/h2,4,6-9,13H,3,5,10-11H2,1H3,(H,31,32)
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n/an/a 964n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%