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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM185584 (US9156852, 1 | USRE47451, Example 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM185584 (US9156852, 1 | USRE47451, Example 1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM185589 (US9156852, 83 | USRE47451, Example 83) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM185585 (US9156852, 16 | USRE47451, Example 16) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM185589 (US9156852, 83 | USRE47451, Example 83) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM185589 (US9156852, 83 | USRE47451, Example 83) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM185586 (US9156852, 38 | USRE47451, Example 38) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM185591 (US9156852, 116 | USRE47451, Example 116) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Discoidin domain-containing receptor 2 (Homo sapiens (Human)) | BDBM185584 (US9156852, 1 | USRE47451, Example 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM185588 (US9156852, 59 | USRE47451, Example 59) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM185591 (US9156852, 116 | USRE47451, Example 116) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM185588 (US9156852, 59 | USRE47451, Example 59) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM185589 (US9156852, 83 | USRE47451, Example 83) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM185586 (US9156852, 38 | USRE47451, Example 38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Discoidin domain-containing receptor 2 (Homo sapiens (Human)) | BDBM185589 (US9156852, 83 | USRE47451, Example 83) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM185591 (US9156852, 116 | USRE47451, Example 116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM185589 (US9156852, 83 | USRE47451, Example 83) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM185585 (US9156852, 16 | USRE47451, Example 16) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM185590 (US9156852, 105 | USRE47451, Example 105) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM185584 (US9156852, 1 | USRE47451, Example 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM185584 (US9156852, 1 | USRE47451, Example 1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM185591 (US9156852, 116 | USRE47451, Example 116) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM185587 (US9156852, 50 | USRE47451, Example 50) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM185590 (US9156852, 105 | USRE47451, Example 105) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM185585 (US9156852, 16 | USRE47451, Example 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM185587 (US9156852, 50 | USRE47451, Example 50) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM185586 (US9156852, 38 | USRE47451, Example 38) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM185588 (US9156852, 59 | USRE47451, Example 59) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Discoidin domain-containing receptor 2 (Homo sapiens (Human)) | BDBM185591 (US9156852, 116 | USRE47451, Example 116) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM185590 (US9156852, 105 | USRE47451, Example 105) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM185591 (US9156852, 116 | USRE47451, Example 116) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM185586 (US9156852, 38 | USRE47451, Example 38) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM185586 (US9156852, 38 | USRE47451, Example 38) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM185590 (US9156852, 105 | USRE47451, Example 105) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Discoidin domain-containing receptor 2 (Homo sapiens (Human)) | BDBM185586 (US9156852, 38 | USRE47451, Example 38) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM185584 (US9156852, 1 | USRE47451, Example 1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM185587 (US9156852, 50 | USRE47451, Example 50) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM185590 (US9156852, 105 | USRE47451, Example 105) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Discoidin domain-containing receptor 2 (Homo sapiens (Human)) | BDBM185590 (US9156852, 105 | USRE47451, Example 105) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 181 | n/a | n/a | n/a | n/a | n/a | n/a |
HANMI PHARM. CO., LTD US Patent | Assay Description The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic... | US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
