Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM50078618 (CHEMBL3415173 | US9278093, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent | Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ... | US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM212442 (US9278093, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent | Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ... | US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM212443 (US9278093, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent | Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ... | US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM212444 (US9278093, 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 21.6 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent | Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ... | US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM50078618 (CHEMBL3415173 | US9278093, 2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent | Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ... | US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM212442 (US9278093, 1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent | Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ... | US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM212443 (US9278093, 3) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.97E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent | Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ... | US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM212444 (US9278093, 4) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent | Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ... | US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D | |||||||||||
More data for this Ligand-Target Pair |