Affinity Data by USPatent=US9296728

USPatent US9296728

Found 26 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092072 (CHEMBL3582419 \| US9296728, 14) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	7.60	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092069 (CHEMBL3582422 \| US9296728, 20) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092073 (CHEMBL3582418 \| US9296728, 13) Show SMILES CCCN(CCC)c1ccc(\C=C(/C#N)C(O)=O)c(OC)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092071 (CHEMBL3582420 \| US9296728, 18) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214697 (US9296728, 19) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092070 (CHEMBL3582421 \| US9296728, 15) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092067 (CHEMBL3582424 \| US9296728, 16) Show SMILES COc1cc(ccc1\C=C(/C#N)C(O)=O)N(CC=C)CC=C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092057 (CHEMBL3582409 \| US9296728, 4) Show SMILES CCCCN(CCCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214695 (US9296728, 10) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214702 (US9296728, 25) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214698 (US9296728, 21) Show SMILES COc1cc(ccc1\C=C(/C#N)C(O)=O)N1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092075 (CHEMBL3582416 \| US9296728, 11) Show SMILES OC(=O)C(=C\c1ccc(cc1)N1CCCC1)\C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092018 (CHEMBL3582410 \| US9296728, 9) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	66	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092078 (CHEMBL3582413 \| US9296728, 7) Show SMILES OC(=O)C(=C\c1ccc(cc1)N(CC=C)CC=C)\C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214696 (US9296728, 17) Show SMILES COc1cc(ccc1\C=C(/C#N)C(O)=O)N(CC#C)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	91	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214705 (US9296728, 29) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092074 (CHEMBL3582417 \| US9296728, 12) Show SMILES OC(=O)C(=C\c1ccc(cc1)N1CCCCC1)\C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092017 (CHEMBL3582411 \| US9296728, 5) Show SMILES CCCCCN(CCCCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214701 (US9296728, 24) Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(CC#C)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214703 (US9296728, 27) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50442702 (CHEMBL2442511 \| US9296728, 26) Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214700 (US9296728, 23) Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(CC=C)CC=C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214699 (US9296728, 22) Show SMILES CCCN(CCC)c1ccc2cc(C(O)=O)c(=O)oc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	299	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092077 (CHEMBL3582414 \| US9296728, 8) Show SMILES OC(=O)C(=C\c1ccc(cc1)N(CC#C)CC#C)\C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214704 (US9296728, 28) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	920	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM50092016 (CHEMBL3582412 \| US9296728, 6) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	950	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
Regents of the University of Minnesota US Patent					More data for this Ligand-Target Pair

* indicates data uncertainty>20%