Affinity Data by USPatent=US9394254

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USPatent US9394254

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fructose-bisphosphate aldolase (Mycobacterium tuberculosis (strain H37Rv))	BDBM382 (1571-30-8 \| 55088_ALDRICH \| 8-hydroxy-2-quinolinec...) Show SMILES OC(=O)c1ccc2cccc(O)c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Denver and Regis University US Patent					Assay Description Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...				US Patent US9394254 (2016) BindingDB Entry DOI: 10.7270/Q2251H3W
The University of Denver and Regis University US Patent					More data for this Ligand-Target Pair
Fructose-bisphosphate aldolase (Mycobacterium tuberculosis (strain H37Rv))	BDBM382 (1571-30-8 \| 55088_ALDRICH \| 8-hydroxy-2-quinolinec...) Show SMILES OC(=O)c1ccc2cccc(O)c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70E+4	6.94E+3	n/a	n/a	n/a	n/a	n/a
The University of Denver and Regis University US Patent					Assay Description Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...				US Patent US9394254 (2016) BindingDB Entry DOI: 10.7270/Q2251H3W
The University of Denver and Regis University US Patent					More data for this Ligand-Target Pair
Fructose-bisphosphate aldolase (Mycobacterium tuberculosis (strain H37Rv))	BDBM32144 (8-quinolinamine \| 8-quinolylamine \| AS-232 \| US100...) Show SMILES Nc1cccc2cccnc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Denver and Regis University US Patent					Assay Description Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...				US Patent US9394254 (2016) BindingDB Entry DOI: 10.7270/Q2251H3W
The University of Denver and Regis University US Patent					More data for this Ligand-Target Pair
Fructose-bisphosphate aldolase (Mycobacterium tuberculosis (strain H37Rv))	BDBM32203 (8-quinolinol \| CHEMBL310555 \| US10005735, Table 1....) Show SMILES Oc1cccc2cccnc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Denver and Regis University US Patent					Assay Description Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...				US Patent US9394254 (2016) BindingDB Entry DOI: 10.7270/Q2251H3W
The University of Denver and Regis University US Patent					More data for this Ligand-Target Pair
Fructose-bisphosphate aldolase (Mycobacterium tuberculosis (strain H37Rv))	BDBM237137 (US9394254, 34) Show SMILES CS(=O)(=O)Nc1ccc2cccc(O)c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	5.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Denver and Regis University US Patent					Assay Description Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...				US Patent US9394254 (2016) BindingDB Entry DOI: 10.7270/Q2251H3W
The University of Denver and Regis University US Patent					More data for this Ligand-Target Pair

Found 1 hit of Isothermal Titration Calorimetry Data.
Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kJ/mole	-TΔS° kJ/mole	ΔH° kJ/mole	log K	pH	Temp °C
Fructose-1,6-bisphosphate aldolase (FBA) (Mycobacterium tuberculosis (strain H37Rv))	BDBM382 (1571-30-8 \| 55088_ALDRICH \| 8-hydroxy-2-quinolinec...)	GoogleScholar PDB	PC cid PC sid		n/a	n/a	-28.7	n/a	n/a	n/a
The University of Denver and Regis University US Patent		GoogleScholar PDB	PC cid PC sid		US Patent US9394254 (2016)

Reorder this table by ΔH°
Reorder this table by -TΔS°
Change energy units to:kcal/mole

* indicates data uncertainty>20%