Affinity Data by USPatent=US9695185

USPatent US9695185

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM206760 (US9260446, (I-S) \| US9695185, I-S) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. US Patent					Assay Description A radiotracer flux assay used to determine ion flux activity of voltage-gated sodium channels in a high-throughput microplate-based format. The assay...				US Patent US9695185 (2017) BindingDB Entry DOI: 10.7270/Q2HD7STB
Xenon Pharmaceuticals Inc. US Patent					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM206762 (US9260446, (II-S) \| US9695185, II-S) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. US Patent					Assay Description A radiotracer flux assay used to determine ion flux activity of voltage-gated sodium channels in a high-throughput microplate-based format. The assay...				US Patent US9695185 (2017) BindingDB Entry DOI: 10.7270/Q2HD7STB
Xenon Pharmaceuticals Inc. US Patent					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM206758 (US9260446, (I) \| US9695185, I) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. US Patent					Assay Description A radiotracer flux assay used to determine ion flux activity of voltage-gated sodium channels in a high-throughput microplate-based format. The assay...				US Patent US9695185 (2017) BindingDB Entry DOI: 10.7270/Q2HD7STB
Xenon Pharmaceuticals Inc. US Patent					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM206761 (US9260446, (II) \| US9695185, II) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. US Patent					Assay Description A radiotracer flux assay used to determine ion flux activity of voltage-gated sodium channels in a high-throughput microplate-based format. The assay...				US Patent US9695185 (2017) BindingDB Entry DOI: 10.7270/Q2HD7STB
Xenon Pharmaceuticals Inc. US Patent					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM206759 (US9260446, (I-R) \| US9695185, I-R) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. US Patent					Assay Description A radiotracer flux assay used to determine ion flux activity of voltage-gated sodium channels in a high-throughput microplate-based format. The assay...				US Patent US9695185 (2017) BindingDB Entry DOI: 10.7270/Q2HD7STB
Xenon Pharmaceuticals Inc. US Patent					More data for this Ligand-Target Pair

* indicates data uncertainty>20%