Affinity Data by PubChem AID=435014

PubChem AID 435014

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM50004233 (5,11-dimethyl-2H-pyrido[4,3-b]carbazole \| CHEMBL12...) Show SMILES Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.49	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM10759 (2-acetoxyethyl(trimethyl)ammonium;bromide \| 2-acet...) Show SMILES CC(=O)OCC[N+](C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.0614	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM73209 ((+)-CIS-DIOXOLANE \| CHEMBL105457 \| MLS000069362 \| ...) Show SMILES C[C@H]1OC[C@@H](C[N+](C)(C)C)O1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.280	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM34572 (BRIMONIDINE \| CHEMBL844 \| MLS000069370 \| SMR000058...) Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 \|t:4\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.0372	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM73210 ((5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]-1-hydroxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.856	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%