Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Cell Reactant: | Serine Hydroxymethyltransferase | ||
Syringe Reactant: | BDBM238 | ||
Meas. Tech.: | Isothermal Titration Calorimetry | ||
Entry Date: | 03/31/03 | ||
ΔG°: | -10.5± (kcal/mole) | ||
pH: | n/a | ||
Log10Kb: | 7.70± n/a | ||
Temperature: | 298.15±n/a (K) | ||
ΔH° : | 5.40± (kcal/mole) | ||
ΔHobs : | 5.40± (kcal/mole) | ||
Ionic Strength: | n/a | ||
not known | |||
Protons Released: | n/a | ||
ΔCp : | -0.36±n/a (kcal/mole) | ||
Stoich. Param.: | n/a | ||
ΔS° : | n/a | ||
Comments: | n/a | ||
Citation | Hom, RK; Huang, T; Gailunas, AF; Wang, C; Mamo, S; Maras, B; Fang, LY; Barra, D; Tung, JS; Walker, DE; Schirch, V; Davis, D; Thorsett, ED; Jewett, NE; Moon, JB; John, V Thermodynamic analysis of the binding of the polyglutamate chain of 5-formyltetrahydropteroylpolyglutamates to serine hydroxymethyltransferase. Biochemistry37:13536-42 (1998) [PubMed] Article | ||
More Info.: | Get all data from this article , ITC RUN data , Solution Info , Data Fit Method , Instrument Info | ||
Serine Hydroxymethyltransferase | |||
Source: | Purified in the laboratory | ||
Purity: | n/a | ||
Prep. Method: | SHMT, about 6 mg/mL, was dialyzed overnight against 20 mM potassium phosphate buffer at pH 7.0, containing 50 mM glycine and 1 mM DTT. This enzyme was then diluted to the desired concentration with the dialysis buffer. | ||
Name: | Serine Hydroxymethyltransferase | ||
Synonyms: | GLYC_RABIT | SHMT1 | ||
Type: | Enzyme | ||
Mol. Mass.: | 52984.86 | ||
Organism: | Oryctolagus cuniculus (rabbit) | ||
Description: | P07511 | ||
Residue: | 484 | ||
Sequence: |
| ||
BDBM238 | |||
Source: | B. Schircks | ||
Purity: | n/a | ||
Prep. Method: | n/a | ||
Name | BDBM238 | ||
Synonyms: | 5-CHO-H4-PteGlu5 | ||
Type | Small organic molecule | ||
Emp. Form. | C40H51N11O19 | ||
Mol. Mass. | 989.8952 | ||
SMILES | Nc1nc2NC[C@H](CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O)C(O)=O)C(O)=O)N(C=O)c2c(=O)[nH]1 | ||
Structure |
Home |
| |
Search |
| |
Deposit |
| |
SiteMap |
| |
About us |
| |
Email us |
| |
Info |
|
©2000 BindingDB. All rights reserved. |